Strychnine hydrochloride, Glycine antagonist ab120416 from Abcam

Product Specs
ItemStrychnine hydrochloride, Glycine antagonist
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120416
Quantity100 mg
Purity0.99

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Implications of variable synaptic weights for rate and temporal coding of cerebellar outputsbioRxivJuly 17, 2023Shuting Wu, Asem Wardak, Mehak M. Khan, Christopher H. Chen, Wade G. Regehrcompound, drug","(R,S)-CPP",Abcam,Ab120160, "Chemical compound, drug",Strychnine hydrochloride,Abcam,Ab120416, "Chemical compound, drug",SR95531 (gabazine),Abcam,Ab120042, "Chemical compound, drug",CGP 55845 hydrochloride

(2) Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic NeuronsCurrent ProtocolsJune 5, 2023Hsiao‐Jou Cortina Chen, Simone Mazzaferro, Tian Tian, Iman Mali, Florian T. Merklein DMSO. Use at 1:200 for a final concentration of 50 μM.Dissolve strychnine hydrochloride (cat. no. ab120416; Abcam) to a stock concentration of 50 mM in sterile water. Use at 1:2500 for a final concentration

(3) Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in miceCommunications biologyMarch 14, 2023Chou MY, Cao X, Hou KC, Tsai MH, Lee CY, Kuo MF, Wu VC, Huang HY, Akbarian S, Chang SK, et al.with the addition of 1 μM TTX (ab120055, Abcam), 5 μM SR95531 (ab120042, Abcam), and 1 μM strychnine (ab120416, Abcam) into the ACSF. The mIPSCs were isolated with 1 μM TTX, 5 mM kynurenic acid (ab120064, Abcam),

(4) Neuronal splicing regulator RBFOX3 mediates seizures via regulating Vamp1 expression preferentially in NPY-expressing GABAergic neuronsProceedings of the National Academy of Sciences of the United States of AmericaAugust 16, 2022Huang DF, Lee CY, Chou MY, Yang TY, Cao X, Hsiao YH, Wu RN, Lien CC, Huang YS, Huang HP, et al.supplemented with 5 mM kynurenic acid (K3375; Sigma), 5 μM SR95531 (1262; Tocris), and 1 μM strychnine (ab120416; Abcam). The internal solution contained 100 mM K-gluconate, 20 mM KCl, 0.2 mM ethylene glycol-bis(beta-aminoethyl

(5) Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca(2+) homeostasis and network synchrony via PMCA2/ATP2B2NeuronFebruary 16, 2022Martín-de-Saavedra MD, Dos Santos M, Culotta L, Varea O, Spielman BP, Parnell E, Forrest MP, Gao R, Yoon S, McCoig E, et al.P0044 Trichloroacetic acid,Sigma-Aldrich,Cat# T8657 Picrotoxin,Abcam,Cat# ab120315 Strychnine,Abcam,Cat# ab120416 Glycine,Sigma-Aldrich,Cat# 50046 NBQX,Tocris,Cat# 1044 TAPI-0,Enzo,Cat# BML-PI133-0001 GM6001,Sigma-Aldrich,Cat#

(6) Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortexeLifeAugust 9, 2021Chong Guo, Stephanie Rudolph, Morgan E Neuwirth, Wade G Regehr,NBQX disodium salt,Abcam,Ab120046, "Chemical compound, drug",(R)-CPP,Abcam,Ab120159, "Chemical compound, drug",Strychnine hydrochloride,Abcam,Ab120416, "Chemical compound, drug",SR95531 (Gabazine),Abcam,Ab120042, "Chemical compound, drug",L-Glutamate,Abcam,Ab120049, "Chemical

(7) Cerebellar and vestibular nuclear synapses in the inferior olive have distinct release kinetics and neurotransmitterseLifeDecember 1, 2020Turecek J, Regehr WG.,NBQX disodium salt,Abcam,Ab120046, "Chemical compound, drug",(R)-CPP,Abcam,Ab120159, "Chemical compound, drug",Strychnine hydrochloride,Abcam,Ab120416, "Chemical compound, drug",SR95531 (Gabazine),Abcam,Ab120042, "Chemical compound, drug",TTA-P2,Alamone

(8) Periaqueductal gray and rostromedial tegmental inhibitory afferents to ventral tegmental area have distinct synaptic plasticity and opiate sensitivityNeuronMay 1, 2020Robyn St. Laurent, Valentina Martinez Martinez Damonte, Ayumi C. Tsuda, Julie A. Kauer(DAMGO)",Tocris,1171 D-(-)-2-Amino-5-phosphonopentanoic acid (APV),Tocris,0106 forskolin,R&D Systems,1099 naloxone,R&D Systems,0599 Strychnine,Abcam,ab120416 tetrodotoxin,Tocris,1078 Deposited Data,Deposited Data,Deposited Data Raw and analyzed data,This

(9) Loss of Doc2b does not influence transmission at Purkinje cell to deep nuclei synapses under physiological conditionseLifeApril 29, 2020Khan MM, Regehr WG.,NBQX disodium salt,Abcam,Ab120046, "Chemical compound, drug",(R)-CPP,Abcam,Ab120159, "Chemical compound, drug",Strychnine hydrochloride,Abcam,Ab120416, "Chemical compound, drug",SR95531 (gabazine),Abcam,Ab120042, "Chemical compound, drug",Tetrodotoxin citrate

(10) Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockoutseLifeMay 15, 2019Raja MK, Preobraschenski J, Del Olmo-Cabrera S, Martinez-Turrillas R, Jahn R, Perez-Otano I, Wesseling JF.compound, drug",picrotoxin,Sigma,Cat# P1675,50 μM "Chemical compound, drug",strychnine,Abcam,Cat# ab120416,0.5 μM "Chemical compound, drug",Advasep-7,Cydex,Cat# ADV7-03A-03105,1 mM "Chemical compound, drug",FM4-64,Biotium,Cat#

(11) Active control of arousal by a locus coeruleus GABAergic circuitNature neuroscienceFebruary 1, 2019Breton-Provencher V, Sur M.resistance ranged from 3 to 5 MΩ. To block glycinergic receptors we bath applied 1 μM of strychnine (ab120416, Abcam) and to block GABAA receptors we applied 20 μM of bicuculline (0131, Tocris). Light activation

(12) Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse DevelopmentNeuronNovember 15, 2017Li J, Han W, Pelkey KA, Duan J, Mao X, Wang YX, Craig MT, Dong L, Petralia RS, McBain CJ, et al.Streptomycin,GIBCO,Cat#: 15140-122 poly-D-lysine,Sigma-Aldrich,Cat#: P6407 Strychnine,Abcam,Cat#: ab120416 APV,Abcam,Cat#: ab120003 DNQX,alomone labs,Cat#: D-131 Tetrodotoxin,BIOTIUM,Cat#: 00060 HiTrap Protein A HP

(13) In vivo transgenic expression of collybistin in neurons of the rat cerebral cortexThe Journal of comparative neurologyApril 1, 2017Fekete CD, Goz RU, Dinallo S, Miralles CP, Chiou TT, Bear J Jr, Fiondella CG, LoTurco JJ, De Blas AL.ab120003, Abcam plc.). Glycinergic inhibitory currents were blocked by 1–2 μM Strychnine (catalog # ab120416, Abcam plc.). For mIPSCs recording, action potential evoked events were blocked by 1 μM TTX (catalog

(14) GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA ReceptorsNeuronMarch 22, 2017Chiu SL, Diering GH, Ye B, Takamiya K, Chen CM, Jiang Y, Niranjan T, Schwartz CE, Wang T, Huganir RL.ab120110; CAS: 53552-05-9 Glycine,Tocris,Cat# 0219; CAS: 5640–6 Strychnine hydrochloride,Abcam,Cat# ab120416; CAS: 1421-86-9 Picrotoxin,Abcam,Cat# ab120315; CAS: 124-87-8 AMPA,Tocris,Cat# 0254; CAS: 83643-88-3 DL-APV,Tocris,Cat#

(15) Neuronal Splicing Regulator RBFOX3 (NeuN) Regulates Adult Hippocampal Neurogenesis and SynaptogenesisPloS oneJanuary 1, 2016Lin YS, Wang HY, Huang DF, Hsieh PF, Lin MY, Chou CH, Wu IJ, Huang GJ, Gau SS, Huang HS.presence of 5 μM SR95531 (Abcam, ab120042), 3μM CGP54626 (Tocris, 1088) and 1μM Strychnine (Abcam, ab120416) and were evoked every 20 s. In each experiment, an input-output (I-O) relationship was plotted by the

(16) RBFOX3/NeuN is Required for Hippocampal Circuit Balance and FunctionScientific reportsDecember 1, 2015Wang HY, Hsieh PF, Huang DF, Chin PS, Chou CH, Tung CC, Chen SY, Lee LJ, Gau SS, Huang HS.continuous recording. To isolate miniature EPSCs (mEPSCs), 1 μM TTX, 5 μM SR95531 and 1 μM strychnine (ab120416, Abcam) were focally applied into the bath through a perfusion valve system (VC-8 valve controller,

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Strychnine hydrochloride, Glycine antagonist from Abcam

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Strychnine hydrochloride, Glycine antagonist from Abcam

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