Anti-Cdk4 antibody [EPR2513Y] ab68266 from Abcam

Product Specs
ItemAnti-Cdk4 antibody [EPR2513Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab68266
Quantity10 UL, 40 UL, 100 UL
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western blot
ClonalityMonoclonal
IsotypeIgG
CloneEPR2513Y
HostRabbit
Antibody TypePrimary
Conjugate/TagUnconjugated
Gene NameCdk4
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
TargetCdk4

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) 7-Ketocholesterol accelerates pancreatic β-cell senescence by inhibiting the SIRT1/CDK4-Rb-E2F1 signaling pathwayIsletsDecember 31, 2023Zhu Q, Wang W, Wu N, He S, Lin X, Zhang W, Zhou J.antibodies against CDKN2A/p16INK4a (ab211542), γ-H2A.X (ab81299), p21 (ab88224), SIRT1 (ab189494), CDK4 (ab68266), and phosphorylated retinoblastoma (p-Rb) protein (ab184796) were from Abcam (Cambridge, UK). The antibodies

(2) Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerabilityResearch SquareApril 28, 2023Shizhong Ke, Fabin Dang, Lin Wang, Jia-Yun Chen, Mandar T. Naik, Abhishek Thavamani, Yansheng Liu, Wenxue Li, Nami Kim, Nandita M. Naik, et al.rabbit monoclonal antibody (ab192036), Anti-RB (ab181616), anti-APC7 (ab4171), anti-CDK4 antibody (ab68266) and anti-Thiophosphate ester (ab133473) antibodies were purchased from Abcam. Monoclonal anti-Flag

(3) Crystal structure of active CDK4-cyclin D and mechanistic basis for abemaciclib efficacynpj Breast CancerNovember 29, 2022Severine Isabelle Gharbi, Laura A. Pelletier, Alfonso Espada, Jesus Gutiérrez, Sonia Maria Gutiérrez Sanfeliciano, Charles T. Rauch, Maria Patricia Ganado, Carmen Baquero, Elisabet Zapatero, Aiping Zhang, et al.(anti-cyclin D1 [Abcam, ab134175], anti-cyclin D3 [Cell Signaling Technology, 2936] or anti CDK4 [Abcam, ab68266]) compared to control condition with beads alone (Supplementary Table 4). Cyclin D1 immunoprecipitation

(4) Long non-coding RNA-PCGEM1 contributes to prostate cancer progression by sponging microRNA miR-129-5p to enhance chromatin licensing and DNA replication factor 1 expressionBioengineeredApril 12, 2022Qiao Fu, Fangfang Wang, Jun Yang, Wei Sun, Zhi Hu, Lv Xu, Hao Chu, Xiao Wang, Wei Zhang(ab202067; Abcam, UK), Bax (ab3191; Abcam), Bcl-2 (ab218123; Abcam), CyclinD1 (ab134175; Abcam), CDK4 (ab68266; Abcam), or GAPDH antibody (ab181602; Abcam) at 4°C overnight. The membrane was incubated with the secondary

(5) Gallium-68 Labeling of the Cyclin-Dependent Kinase 4/6 Inhibitors as Positron Emission Tomography Radiotracers for Tumor ImagingACS OmegaNovember 30, 2021Cheng Liu, Ziyi Yang, Mingyu Liu, Xiangwei Wang, Shaoli Song, Xiaoping Xu, Zhongyi Yangimmunofluorescence techniques, the adjacent slides were fixed with 4% paraformaldehyde in PBS and stained with anti-CDK4 (ab68266, Abcam) and anti-CDK6 antibodies (ab68266, Abcam). The sections were placed in a humidified chamber

(6) LncRNA-CCDC144NL-AS1 Promotes the Development of Hepatocellular Carcinoma by Inducing WDR5 Expression via Sponging miR-940Journal of Hepatocellular CarcinomaMay 3, 2021Yingying Zhang, Hongyu Zhang, Shuhuan Wuprobed with WDR5 (ab245479, Abcam, USA), CDK1 (ab201008, Abcam, USA), CDK2 (ab32147, Abcam, USA), CDK4 (ab68266, Abcam, USA), MMP2 (ab86607, Abcam, USA), and MMP9 (ab237782, Abcam, USA) overnight at 4°C, followed

(7) TMPO-AS1, a Novel E2F1-Regulated lncRNA, Contributes to the Proliferation of Lung Adenocarcinoma Cells via Modulating miR-326/SOX12 AxisCancer Management and ResearchDecember 2, 2020Lin Wei, Yugang Liu, Huijun Zhang, Yuefeng Ma, Zenghui Lu, Zhenning Gu, Chao Dingas follows: anti-SOX12 (ab54371, Abcam; 1:500), anti-Cyclin D1 (ab40754, Abcam; 1:2000), anti-CDK4 (ab68266, Abcam; 1:500), anti-CDK6 (ab124821, Abcam; 1:50,000) anti-GAPDH (ab8245, Abcam; 1:1000), HRP-conjugated

(8) Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cellsBiological researchJuly 5, 2019Wang X, Peng P, Pan Z, Fang Z, Lu W, Liu X.were purchased from Sungen Biotech (Tianjing, China). CyclinD1 (ab134175), CyclinE1 (ab33911), CDK4 (ab68266), Bax (ab182733) and Bcl-2 (ab182858) antibodies were purchased from Abcam (Cambridge, MA, USA). GRP78

(9) Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cellsCancer Management and ResearchMay 23, 2019Khuloud Bajbouj, Jasmin Shafarin, Mawieh Hamad(antihepcidinab57611; anti-Fpn, ab85370; anti-TfR 1, ab84036; anti-TfR2, ab84287; antisurvivin134170; antiCDK4, ab68266; anti-cdk6, ab151247; anti–cyclinD1, ab134175; anti-CHK1, ab47574; anti-phospho-CHK1, ab5856; Abcam,

(10) Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in HepatocytesHepatology communicationsMarch 1, 2019Wu H, Ploeger JM, Kamarajugadda S, Mashek DG, Mashek MT, Manivel JC, Shekels LL, Lapiro JL, Albrecht JH.(Billerica, MA). Anti‐lysosomal‐associated membrane protein 1 (LAMP1; catalog #ab24170), anti‐CDK4 (catalog #ab68266), anti‐abhydrolase domain containing 5 (ABHD5; catalog #ab183739), and anti‐G0/G1 switch gene 2 (G0S2;

(11) CDK4 inhibition diminishes p53 activation by MDM2 antagonistsCell death & diseaseSeptember 11, 2018Sriraman A, Dickmanns A, Najafova Z, Johnsen SA, Dobbelstein M.

(12) Effect of Period 2 on the proliferation, apoptosis and migration of osteosarcoma cells, and the corresponding mechanismsOncology lettersAugust 1, 2018Qin T, Lu XT, Li YG, Liu Y, Yan W, Li N, Sun YY.(dilution, 1:500; cat no. 9664s; Cell Signaling Technology), rabbit anti‑CDK4 (dilution, 1:500; cat no. ab68266; Abcam) and mouse anti‑β‑actin (dilution, 1:1,000; cat no. 4970s; Cell Signaling Technology). The membranes

(13) Long non-coding RNA OIP5-AS1 promotes proliferation of lung cancer cells and leads to poor prognosis by targeting miR-378a-3pThoracic CancerAugust 1, 2018Maolong Wang, Xiao Sun, Yuling Yang, Wenjie Jiaobinding was blocked with 5% skim milk for two hours at 37°C. Anti‐CDK4 polyclonal antibody (1:1000, ab68266), anti‐CDK6 (1:1000, ab131469), and anti‐Ki67 (1:1000, ab92742; Abcam, Cambridge, UK) were then used

(14) Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cellsJournal of Ginseng ResearchJuly 1, 2017Chih-Jung Yao, Jyh-Ming Chow, Shuang-En Chuang, Chia-Lun Chang, Ming-De Yan, Hsin-Lun Lee, I-Chun Lai, Pei-Chun Lin, Gi-Ming Laipurchased from Cell Signaling (Danvers, MA, USA). Primary antibodies for cyclin-dependent kinase (CDK)4 (ab68266), CDK6 (ab124821), cyclin D1 (ab134175), glyceraldehyde 3-phosphate dehydrogenase (ab8245), and Bcl-2

(15) Modeling high-grade serous ovarian carcinogenesis from the fallopian tubeProceedings of the National Academy of Sciences of the United States of AmericaMay 3, 2011Karst AM, Levanon K, Drapkin R.

Be the First to Write a Review!

Anti-Cdk4 antibody [EPR2513Y] from Abcam

Abcam

Citations (15)

Reviews

Anti-Cdk4 antibody [EPR2513Y] from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map