Fig 1: NP and PP affect the generation of extracellular matrix components. (A) Representative images of dermal papilla structure in the different pressure treatment groups. (B) Protein expression of different matrix components in wound tissues treated with different pressure types. Different time points (day 3, 7, 10 and 14) were recorded. Statistical quantification of IOD value of (C) collagen I, (D) collagen III, (E) UgI-Y3 (FN), (F) MMP-13, (G) TIMP-1, (H) TIMP-2. Data are presented as the means ± SEM, n=3 experiments. ***P<0.001, **P<0.01, *P<0.05, compared with the control. ???P<0.001, ??P<0.01, compared with NP. NP, negative pressure; PP, positive pressure; IOD, integrated option density.
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