Fig 1: Verification of differentially expressed proteins using western blotting. (A) Representative western blots demonstrate the expression levels of LTF, DEFA1, S100A7 and S100A9 in the MV/E isolated from the CSF. Histogram data shows the densitometric semi-quantification (mean ± SD) of (B) LTF, (C) DEFA1, (D) S100A7 and (E) S100A9 expression levels. Protein densitometric semi-quantification was normalized to the density of CD9 protein. CD9 is an exosome surface marker. *P<0.05. LTF, lactoferrin; DEFA1, a defensin 1; MV/E, microvesicle/exosome.