Fig 1: Immunohistochemistry of SEGA (OCT-4 and INI-1)OCT-4 cytoplasmic positivity was observed in endothelial cells, pericytes (P), and astrocytic type-cell (A) appearance, in close contact with giant cell tumor (arrow). Magnification, 400×; tumor cells showed positive cytoplasmic staining with antibodies to INI-1 and hamartin (100×); tuberin showed both positive and negative cytoplasm staining in tumor cells (100×).OCT-4, octamer-binding transcription factor 4; INI-1, integrase interactor 1; SEGA, subependymal giant cell astrocytoma