Fig 2: IHC co-localization of astrocytes (GFAP) with IL-10 using both direct IL-10 antibody and IL-10/GFP reporter. Left panels depict direct IL-10 antibody, right panels depict reporter. Arrowheads indicate areas of co-localization. Dpo = days post operation, C = control (left) FMNuc, Ax = axotomized (right) FMNuc.

Fig 3: Statins alter mRNA expression in differentiating NSPCs through a non-CBP dependent mechanism.Average mRNA expression of the neuronal markers (A) Map2 (n = 6), (B) Tuj1 (n = 6), astrocyte marker (C) GFAP (n = 6), and oligodendrocyte marker (D) Olig2 (n = 6) after four days of NSPC differentiation in 10 uM prava. Average mRNA expression of the neuronal markers (E) Map2 (n = 6) and (F) Tuj1 (n = 6) as well as the astrocyte marker (G) GFAP (n = 6) and oligodendrocyte marker (H) Olig2 (n = 6) after four days of NSPC differentiation in 1uM simva. (I) Average mRNA expression of GFAP in cells after four days of differentiation in 10uM prava co-treated with 1 uM or 10 uM FPP (n = 5). (J) Average mRNA expression of Ldlr in cells after four days of differentiation in 10 uM prava co-treated with 1 uM or 10 uM FPP (n = 5). (*p<0.05, **p<0.01, ***p<0.001 compared to vehicle unless otherwise indicated by brackets).