Fig 2: Scoring for Endocan-MVD. Low power view showing representative fields of epithelial ovarian cancer of intratumoural and peritumoural microvessels stained by endocan immunohistochemistry: A, B, C & D. Some of the representative microvessels are indicated by the arrow. Endocan immunohistochemical stain, magnification 200x

Fig 3: Validation of the role of ESM1 in CRC. (A) Venn diagram of prognosis-related genes in three datasets and screening characteristic genes in three datasets. (B) Validation of ESM1 gene expression in various cell lines by qPCR. (C, D) Western blot and the quantification of ESM1 protein expression in various cell lines. (E, F) Western blot and the quantification of ESM1 in CRC tumor tissues. *P < 0.05. (G) Kaplan-Meier survival analysis of ESM1 in different groups. (H) Representative images of ESM1 immunohistochemical staining (-: negative staining, +: weak positive, ++: medium positive, +++: strong positive. Scale bars: up, 2000 µm; below, 50 µm).