Meprin alpha Subunit/MEP1A Antibody AF3220 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMeprin alpha Subunit/MEP1A Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF3220
NCBI Gene AliasesPPHA
ApplicationsWestern Blot, Immunohistochemistry, Immunoprecipitation, Intracellular Staining by Flow Cytometry, CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
HostGoat
ReactivityHuman
Quantity100 ug (also 25 ug)
TargetMeprin alpha Subunit/MEP1A
NCBI Full Gene Namemeprin A subunit alpha
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human Meprin alpha Subunit/MEP1A, Val22-Gln601, Accession # AAA21338
ConcentrationLYOPH
PurityImmunogen affinity purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human Meprin alpha Subunit/MEP1A in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse MEP1A and recombinant human MEP1B is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Tracking cellular and molecular changes in a species-specific manner during experimental tumor progression in vivoOncotargetMarch 23, 2018Indersie E, Hooks KB, Capdevielle C, Fabre M, Dugot-Senant N, Desplat A, Lepreux S, Merched A, Grosset CF, Hagedorn M.M7240), anti-Caspase 3 activated (1:200, R&D Systems, AF835) and anti-Meprin-1α (1:100, R&D Systems, AF3220). HRP-coupled secondary antibodies were from the EnVisionTM FLEX kit (Dako) and for anti-Meprin1A, an

(2) Meprin β contributes to collagen deposition in lung fibrosisScientific reportsJanuary 6, 2017Biasin V, Wygrecka M, Marsh LM, Becker-Pauly C, Brcic L, Ghanim B, Klepetko W, Olschewski A, Kwapiszewska G.

(3) Basement membrane protein nidogen-1 is a target of meprin β in cisplatin nephrotoxicityToxicology LettersJuly 16, 2015Christian Herzog, Raju Marisiddaiah, Randy S. Haun, Gur P. Kaushalother chemicals were from Sigma-Aldrich unless specified otherwise. The antibodies against meprin α (AF3220 and AF4007), meprin β (AF3300), and pro-meprin β (MAB 28592) were from R&D Systems (Minneapolis, MN).

(4) ADAM10 is the major sheddase responsible for the release of membrane-associated meprin AThe Journal of biological chemistryMay 9, 2014Herzog C, Haun RS, Ludwig A, Shah SV, Kaushal GP.

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Meprin alpha Subunit/MEP1A Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Meprin alpha Subunit/MEP1A Antibody from R&D Systems, a Bio-Techne Brand

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