Fig 2: Expression profile of GC cell lines. (A) Expression status of DPYSL3 and potentially interacting genes in GC cell lines. Differential mRNA expression in GC cell lines was observed. Error bars indicated standard deviation among three biological replicates. (B) Correlative analysis between the mRNA expression levels of DPYSL3 and those of VEGF, FAK, EZR and c-SRC.

Fig 3: Prognostic impact ofDPYSL3mRNA expression in GC patients. (A) The high DPYSL3 mRNA expression group had significantly shorter disease specific survival than the low expression group. (B) Recurrence free survival was significantly shortened in the high DPYSL3 mRNA expression group. (C) Curves comparing the disease specific survival of patient groups categorized by expression level of DPYSL3 mRNA in each tumor differentiation.

Fig 4: Detection ofDPYSL3protein. (A) Representative cases of each DPYSL3 staining intensity; no staining, minimal, focal and diffuse (400× magnification). (B) A positive correlation was observed between the expression level of DPYSL3 mRNA and the staining intensity in GC tissues.