Fig 2: Liver immunostaining using rat-positive/mouse negative CK19 at 8 weeks after administration of CLiPs. The mice were grouped as follows: The mice were grouped as follows: a, continuation of high-fat diet with the administration of CLiPs; b, continuation of high-fat diet without the administration of CLiPs; c, discontinuation of high-fat diet with the administration of CLiPs, d, discontinuation of high-fat diet without the administration of CLiPs. a': Positive cells were observed in mice of group a. c': Positive cells were observed in the mice of group c.