Description
Product Characteristics: MAML1, mastermind-like 1 (Drosophila), Mam1, Mam-1, KIAA0200, mastermind homolog, mastermind-like 1
Target Information: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]