pIgR Antibody AF2800 from R&D Systems, a Bio-Techne Brand

Product Specs
ItempIgR Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF2800
ApplicationsWestern Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction
Quantity100 ug (also 25 ug)
IsotypeIgG
TargetpIgR
ReactivityMouse
HostGoat
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
NCBI Full Gene Namepolymeric immunoglobulin receptor
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse pIgR, Lys19-Lys645, Accession # O70570
ConcentrationLYOPH
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse pIgR in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human pIgR is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9bCell Reports MedicineOctober 18, 2022Shikai Hu, Silvia Liu, Yu Bian, Minakshi Poddar, Sucha Singh, Catherine Cao, Jackson McGaughey, Aaron Bell, Levi L. Blazer, Jarret J. Adams, et al.Cyclin D1 (Abcam, ab134175, 1:200), RGN (Santa Cruz Biotechnology, sc-390098, 1:100), PIGR (R&D Systems, AF2800, 1:100) for 1 h at room temperature. Samples were washed with PBS three times and incubated with the

(2) Lung immunoglobulin A immunity dysregulation in cystic fibrosisEBioMedicineOctober 1, 2020Collin AM, Lecocq M, Noel S, Detry B, Carlier FM, Aboubakar Nana F, Bouzin C, Leal T, Vermeersch M, De Rose V, et al.

(3) Dietary Soy Protein Isolate Attenuates Intestinal Immunoglobulin and Mucin Expression in Young Mice Compared with CaseinNutrientsSeptember 8, 2020Zeng B, Wang D, Wang H, Chen T, Luo J, Xi Q, Sun J, Zhang Y.

(4) Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota ManipulationCell host & microbeMarch 11, 2020Yang C, Mogno I, Contijoch EJ, Borgerding JN, Aggarwala V, Li Z, Siu S, Grasset EK, Helmus DS, Dubinsky MC, et al.(1/300 dilution; eBioscience, clone mA-6E1), goat anti-mouse pIgR (1/500 dilution; R&D Systems, cat #: AF2800). Slides were washed in PBS for three times, incubated with Alexa Fluor®-conjugated species-specific

(5) Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular InflammationImmunitySeptember 17, 2019Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, et al.following antibodies: IgA (A90–103P; Bethyl Laboratories), CD31 (390; eBioscience or abcam ab28364), pIgR (AF2800; R&D systems) and C3 (11H9; Abcam). Jejunum and colon tissues were fixed in 10% formalin, and processed

(6) Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cellsNatureJuly 1, 2018Bornstein C, Nevo S, Giladi A, Kadouri N, Pouzolles M, Gerbe F, David E, Machado A, Chuprin A, Tóth B, et al.

(7) Loss of CD14 leads to disturbed epithelial-B cell crosstalk and impairment of the intestinal barrier after E. coli Nissle monoassociationScientific reportsJanuary 15, 2018Basic M, Buettner M, Keubler LM, Smoczek A, Bruesch I, Buchheister S, Bleich A.

(8) Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfacesJCI insightAugust 17, 2017Azzam KM, Madenspacher JH, Cain DW, Lai L, Gowdy KM, Rai P, Janardhan K, Clayton N, Cunningham W, Jensen H, et al.A3854), goat anti-IgA HRP (1:1,000; Abcam, ab97235), or goat anti-pIgR (1:1,000; R&D Systems/Bio-techne, AF2800). Membranes were then washed and the latter target exposed (60 minutes) to 1:5,000 HRP-conjugated secondary

(9) Protection of Human Colon Cells from Shiga Toxin by Plant-based Recombinant Secretory IgAScientific reportsApril 3, 2017Nakanishi K, Morikane S, Ichikawa S, Kurohane K, Niwa Y, Akimoto Y, Matsubara S, Kawakami H, Kobayashi H, Imai Y.

(10) Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung diseaseMucosal ImmunologyMarch 1, 2017Alessandra Livraghi-Butrico, Barbara R. Grubb, Kristen J. Wilkinson, Allison S. Volmer, Kimberly A. Burns, Christopher M. Evans, Wanda K. O’Neal, Richard C. Boucherin PBS-T, for 1 hr at RT. Primary antibodies and isotype control (goat anti-mouse pIgR R&D Systems AF2800 and goat IgG Jackson ImmunoResearch 0.2 mg/ml) were diluted in 5% NDS in PBST and incubated over night

(11) Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney DiseaseThe Journal of biological chemistryJune 19, 2015Olsan EE, Matsushita T, Rezaei M, Weimbs T.

(12) Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variationNatureMay 7, 2015Moon C, Baldridge MT, Wallace MA, D CA, Burnham, Virgin HW, Stappenbeck TS.antibody at 4°C overnight. Primary antibodies include: goat anti-mouse pIgR (1/500, R&D Systems, catalog #AF2800) and goat anti-mouse IgA-AlexaFluor488 (1/200, Serotec, catalog #STAR137F). The slides were rinsed three

(13) Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosisMucosal immunologyJuly 1, 2014Moon C, VanDussen KL, Miyoshi H, Stappenbeck TS.

(14) Aldehyde dehydrogenase activity enriches for proximal airway basal stem cells and promotes their proliferationStem cells and developmentMarch 15, 2014Hegab AE, Ha VL, Bisht B, Darmawan DO, Ooi AT, Zhang KX, Paul MK, Kim YS, Gilbert JL, Attiga YS, et al.

(15) IL-25 Improves IgA Levels During Parenteral Nutrition Through the JAK-STAT PathwayAnnals of SurgeryDecember 1, 2013Aaron F. Heneghan, Joseph F. Pierre, Kenneth A. Kudskroom temperature. Sections were incubated with pIgR primary antibody (1:100, Goat anti-mouse polyclonal antibody, AF2800, R&D Systems, Minneapolis, MN) in 1% BSA with PBS for 1 hour at room temperature. Sections were rinsed

(16) Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptidesMucosal immunologySeptember 1, 2012Frantz AL, Rogier EW, Weber CR, Shen L, Cohen DA, Fenton LA, Bruno ME, Kaetzel CS.

(17) Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthmaBiomarker insightsJanuary 1, 2012Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, et al.

(18) Efficacy of poly[di(sodium carboxylatophenoxy)phosphazene] (PCPP) as mucosal adjuvant to induce protective immunity against respiratory pathogensVaccineMarch 8, 2010Shim DH, Ko HJ, Volker G, Potter AA, Mutwiri G, Babiuk LA, Kweon MN.

(19) The member of the cyclic di-nucleotide family bis-(3', 5')-cyclic dimeric inosine monophosphate exerts potent activity as mucosal adjuvantVaccineMarch 2, 2010Libanova R, Ebensen T, Schulze K, Bruhn D, Nörder M, Yevsa T, Morr M, Guzmán CA.

(20) Adjuvant effects of ambient particulate matter monitored by proteomics of bronchoalveolar lavage fluidProteomicsFebruary 1, 2010Kang X, Li N, Wang M, Boontheung P, Sioutas C, Harkema JR, Bramble LA, Nel AE, Loo JA.

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pIgR Antibody

pIgR Antibody

pIgR Antibody

pIgR Antibody

pIgR Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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pIgR Antibody from R&D Systems, a Bio-Techne Brand

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