Guinea pig Anti-NMDAR1 (GluN1) (extracellular) Antibody AGC-001-GP from Alomone Labs, Ltd.

Description

Alomone Labs is pleased to offer a highly specific antibody directed against an extracellular epitope of rat NMDA Receptor 1. Guinea pig Anti-NMDAR1 (GluN1) (extracellular) Antibody (#AGC-001-GP) raised in guinea pig can be used in western blot and immunohistochemistry applications. The antibody recognizes an extracellular epitope and is thus ideal for detecting NMDAR1 in living cells. It has been designed to recognize NMDAR1 from rat, mouse and human samples. The antigen used to immunize guinea pigs is the same as Anti-NMDAR1 (GluN1) (extracellular) Antibody (#AGC-001) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc

Product Specs
ItemGuinea pig Anti-NMDAR1 (GluN1) (extracellular) Antibody
CompanyAlomone Labs, Ltd.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAGC-001-GP
FormatReconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3., Lyophilized Powder
ApplicationsIF, IHC, WB
ValidationAs per applications, See images, contact for clarifications
Quantity1 X 25 mcl, 1 X 50 mcl, 1 X 0.2 ml
PurityAffinity purified on immobilized antigen
NCBI Full Gene Nameglutamate ionotropic receptor NMDA type subunit 1
NCBI Gene AliasesGluN1, NMDAR1, NR1
Antibody TypePrimary
ClonalityPolyclonal
ReactivityHuman (Tested);Mouse (Tested);Rat (Tested)
Domain/Region/Terminusextracellular
ImmunogenSynthetic peptide
Research Area0
Conjugate/TagUnconjugated
HostGuinea Pig
Concentration08 mg/ml
IsotypeIgG
pH RangepH 7.4

Specifications/Features

starting price for North American orders, for exact pricing view product page

Sequence

ETEKPRGYQMSTRLK(C), corresponding to amino acid residues 385-399 of rat GluN1

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Alomone Labs, Ltd.

PO Box 4287

Jerusalem 91042

Israel

Phone: +972-2-587-2202
+972-2-587-1101

Company Profile

Website: http://www.alomone.com/

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(3) Astrocyte GluN2C NMDA receptors control basal synaptic strengths of hippocampal CA1 pyramidal neurons in the stratum radiatumeLifeOctober 25, 2021Chipman PH, Fung CCA, Pazo Fernandez A, Sawant A, Tedoldi A, Kawai A, Ghimire Gautam S, Kurosawa M, Abe M, Sakimura K, et al.

(4) Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid ModulationFrontiers in pharmacologyJanuary 1, 2021Langer K, Müller-Längle A, Wempe J, Laube B.

(5) Effects of Aging on the Structure and Expression of NMDA Receptors of Somatostatin Expressing Neurons in the Mouse HippocampusFrontiers in aging neuroscienceJanuary 1, 2021Gramuntell Y, Klimczak P, Coviello S, Perez-Rando M, Nacher J.

(6) Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitorsThe Journal of experimental medicineOctober 1, 2018Nestor J, Arinuma Y, Huerta TS, Kowal C, Nasiri E, Kello N, Fujieda Y, Bialas A, Hammond T, Sriram U, et al.

(7) Stress hormone rapidly tunes synaptic NMDA receptor through membrane dynamics and mineralocorticoid signallingScientific reportsAugust 14, 2017Mikasova L, Xiong H, Kerkhofs A, Bouchet D, Krugers HJ, Groc L.

(8) Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptorsCell death & diseaseNovember 10, 2016Lesept F, Chevilley A, Jezequel J, Ladépêche L, Macrez R, Aimable M, Lenoir S, Bertrand T, Rubrecht L, Galea P, et al.

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