Anti-8-Hydroxyguanosine antibody [15A3] GTX41980 from GeneTex

Product Specs
ItemAnti-8-Hydroxyguanosine antibody [15A3]
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX41980
FormatPBS, 50% Glycerol, no preservative
ApplicationsICC/IF, IHC-P, IHC-Fr, FACS, IP, Dot, ELISA, Activation, IHC
Conjugate/TagUnconjugated
HostMouse
ClonalityMonoclonal
Clone15A3
Immunogen8-hydroxy-guanosine-BSA and –casein conjugates
Quantity100 µg
Concentration1mg/ml
IsotypeIgG2b
Antibody TypePrimary Antibodies
PurityProtein G Purified
Target8-Hydroxyguanosine
NCBI Full Gene Name8-Hydroxyguanosine
NCBI Gene Aliases8OHdG, 8 hydroxyguanine, 80G, 8-OH-dG, 8OHG, 8 Hydroxyguanosine, 8 OHdG, 8hydroxyguanine, 8 OH dG
Research AreaCell Biology, Metabolism
ReactivitySpecies independent

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) VDR alleviates endothelial cell injury in arteriovenous fistula through inhibition of P66Shc-mediated mitochondrial ROSScientific reportsJuly 8, 2023Han YC, Liu YT, Zhang H, Xu Y, Liu J, Chen H, Song N, Qin DL, Yang S.Affinity Biotechnology (Cincinnati, USA). Anti-Pin1 antibody (GTX113245) and anti-8-OHdG antibody (GTX41980) were purchased from GeneTex, Inc (USA). Anti-Vitamin D receptor antibody(ab3508) was purchased from

(2) Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non-Amplification of Activin A-ACVR2B-NOX4 Axis PathwayAdvanced science (Weinheim, Baden-Wurttemberg, Germany)May 1, 2023Jeon J, Lee H, Jeon MS, Kim SJ, Choi C, Kim KW, Yang DJ, Lee S, Bae YS, Choi WI, et al.cartilage sections, immunohistochemical staining was performed with 8‐hydroxy‐2’‐deoxyguanosine (8‐OhdG; GTX41980, GeneTex, Irvine, CA, USA). Statistical Analysis All experiments were performed independently at least

(3) TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signallingJHEP reports : innovation in hepatologyMay 1, 2023Su W, Gao W, Zhang R, Wang Q, Li L, Bu Q, Xu Z, Liu Z, Wang M, Zhu Y, et al.from 2 weeks of age to 4 weeks of age. For anti-8-hydroxydeoxyguanosine (anti-8-OHdG) antibody (cat# GTX41980, GeneTex, CA, USA) treatment, anti-8-OHdG antibody (5 mg/kg body weight) and control IgG (5 mg/kg, cat#

(4) Evaluation of renal damage in a bleomycin-induced murine model of systemic sclerosisIran J Basic Med SciJanuary 1, 2023Dulce Carolina Pérez-Figueroa, Edilburga Reyes-Jiménez, Juan Manuel Velázquez-Enríquez, Itayetzi Reyes-Avendaño, Karina González-García, Saúl Villa-Treviño, Honorio Torres-Aguilar, Rafael Baltiérrez-Hoyos, Verónica Rocío Vásquez-GarzónAfter blocking nonspecific sites with 5% BSA, the primary monoclonal mouse anti-8-OHdG antibody (1:200; GTX41980; GeneTex, Irvine, TX, USA) was added. Subsequently, the same protocol was followed as in the previous

(5) The Eyelid Meibomian Gland Deficiency in Fucosyltransferase 1 Knockout MiceInternational journal of molecular sciencesAugust 21, 2022Yoon CH, Ryu JS, Ko JH, Kim YK, Oh JH, Chung JH, Oh JY.Carlsbad, CA, USA), PPARγ (a marker for meibocytes, #ab59256, Abcam, Cambridge, MA, USA) and 8-OHdG (#GTX41980, GeneTex, Irvine, CA, USA). The LipidTOX+ MG acinar area and the number of PPARγ+ cells per acinus were

(6) Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathwayNature communicationsDecember 11, 2020Dai E, Han L, Liu J, Xie Y, Zeh HJ, Kang R, Bai L, Tang D.randomly allocated into groups and injected i.p. with mouse monoclonal anti-8-OHG antibody (10 mg/kg; #GTX41980, RRID:AB_10732443, GeneTex) and control IgG2B (10 mg/kg; #MAB004, RRID:AB_357346, R&D Systems) per week

(7) Mitochondria targeted peptide SS-31 prevent on cisplatin-induced acute kidney injury via regulating mitochondrial ROS-NLRP3 pathwayBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieOctober 1, 2020Yang SK, Han YC, He JR, Yang M, Zhang W, Zhan M, Li AM, Li L, Na-Song, Liu YT, et al.

(8) Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse ModelInternational journal of molecular sciencesJune 11, 2020Yoon CH, Ryu JS, Hwang HS, Kim MK.LipidTOX (H34475; Invitrogen, Carlsbad, CA, USA), PPAR-γ (Ab59256; Abcam, Cambridge, MA, USA), and 8-OHdG (GTX41980; GeneTex, Irvine, TX, USA). 4.4. Transillumination Meibography of Mice After euthanasia, both upper

(9) Arsenic trioxide, a cancer chemo drug hampers fibrotic liver regeneration by interrupting oxidative stress rekindling and stellate cell rejuvenationJournal of cellular physiologyFebruary 1, 2020Nithyananthan S, Thirunavukkarasu C.

(10) Helminth-derived molecules inhibit colitis-associated colon cancer development through NF-κB and STAT3 regulationInternational journal of cancerDecember 1, 2019Callejas BE, Mendoza-Rodríguez MG, Villamar-Cruz O, Reyes-Martínez S, Sánchez-Barrera CA, Rodríguez-Sosa M, Delgado-Buenrostro NL, Martínez-Saucedo D, Chirino YI, León-Cabrera SA, et al.

(11) Troxerutin with copper generates oxidative stress in cancer cells: Its possible chemotherapeutic mechanism against hepatocellular carcinomaJournal of cellular physiologyMarch 1, 2018Subastri A, Suyavaran A, Preedia Babu E, Nithyananthan S, Barathidasan R, Thirunavukkarasu C.

(12) Nimbolide attenuate the lipid accumulation, oxidative stress and antioxidant in primary hepatocytesMolecular biology reportsDecember 1, 2017Alshammari GM, Balakrishnan A, Chinnasamy T.

(13) Linking arsenite- and cadmium-generated oxidative stress to microsatellite instability in vitro and in vivoFree radical biology & medicineNovember 1, 2017Wu CL, Huang LY, Chang CL.

(14) Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injuryAmerican journal of physiology. Lung cellular and molecular physiologyMay 1, 2017Teng RJ, Jing X, Michalkiewicz T, Afolayan AJ, Wu TJ, Konduri GG.

(15) O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic HeartsThe Journal of biological chemistryDecember 16, 2016Cividini F, Scott BT, Dai A, Han W, Suarez J, Diaz-Juarez J, Diemer T, Casteel DE, Dillmann WH.

(16) Expression of the mitochondrial calcium uniporter in cardiac myocytes improves impaired mitochondrial calcium handling and metabolism in simulated hyperglycemiaAmerican journal of physiology. Cell physiologyDecember 1, 2016Diaz-Juarez J, Suarez J, Cividini F, Scott BT, Diemer T, Dai A, Dillmann WH.1⫻ PBS] before incubation overnight at 4°C with anti-8hydroxy-2=-deoxyguanosine (8-OHdG; product no. GTX41980, Genetex) diluted 1:20 in 1:10 blocking-and-permeabilization buffer. As control for nonspecific detection

(17) Combination of 2-deoxy d-glucose and metformin for synergistic inhibition of non-small cell lung cancer: A reactive oxygen species and P-p38 mediated mechanismBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieDecember 1, 2016Hou XB, Li TH, Ren ZP, Liu Y.

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Anti-8-Hydroxyguanosine antibody [15A3]

Anti-8-Hydroxyguanosine antibody [15A3]

Anti-8-Hydroxyguanosine antibody [15A3] from GeneTex

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GeneTex

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Anti-8-Hydroxyguanosine antibody [15A3] from GeneTex

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