Fig 1: Immunohistochemical staining for p-p38, CYP2J2, and sEH in normal and colorectal carcinoma samples. Representative micrographs of grade 2 tumours and corresponding normal tissue samples were obtained from the same patient (male, 55 years old). Magnification ×100, white line represents 100 µm. Graphs show immunohistochemical staining intensities (n = 18): columns show medians, dots show individual samples. Immunostaining intensities were scored semiquantitatively as: 0 negative staining, 1 weak staining, 2 moderate staining, 3 strong staining. Immunostaining for p-p38 was scored separately for nucleus and cytoplasm, CYP2J2 and sEH were scored in cytoplasm. Comparison of staining intensity between normal and carcinoma tissues was performed by the Wilcoxon signed rank test at a significance level of p = 0.05. Statistically significant results are marked with *, p-values are given directly in the graphs, ns—nonsignificant result.