Fig 1: CETN2 specifically labels astrocytes. (A–A”) CETN2 labeling overlaps with canonical astrocytic marker GFAP in human prefrontal cortex sections. (B–D) CETN2 specificity is confirmed by a lack of co-localization with neuronal protein RNA-binding fox-1 homolog 3 (RBFOX3), microglial marker ionized calcium-binding adaptor molecule 1 (IBA1), and mature oligodendrocyte marker adenomatous polyposis coli (APC). (E–H) Scatterplot correlation graphs showing robust co-localization of CETN2 with GFAP and poor overlap with RBFOX3, as well as with IBA1 and APC. Pearson’s coefficients are indicated on each plot. (I) Histogram shows CETN2 co-localization percentages with other neuronal and non-neuronal cell types. Data represent mean ± SEM. Scale bar: (A–D) 20 µm.