N-Cadherin Antibody AF6426 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemN-Cadherin Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF6426
NCBI Gene AliasesCDw325, ADHD8, CDHN, ACOGS, ARVD14, NCAD, CD325
Conjugate/TagUnconjugated
ReactivityHuman, Mouse, Rat
TargetN-Cadherin
ApplicationsWestern Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, CyTOF-ready
IsotypeIgG
Quantity100 ug (also 25 ug)
HostSheep
NCBI Full Gene Namecadherin 2
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant human N-Cadherin, Asp160-Ala724, Accession # P19022
ConcentrationLYOPH
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human, mouse, and rat N-Cadherin in Western blots. In direct ELISA, less than 10% cross-reactivity with recombinant human (rh) E-Cadherin, and rhR-Cadherin is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) An integrated organoid omics map extends modeling potential of kidney diseaseNature communicationsAugust 14, 2023Lassé M, El Saghir J, Berthier CC, Eddy S, Fischer M, Laufer SD, Kylies D, Hutzfeldt A, Bonin LL, Dumoulin B, et al.

(2) VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidneyScience SignalingNovember 29, 2022Markus M. Rinschen, Jennifer L. Harder, Madalina E. Carter-Timofte, Luis Zanon Zanon Rodriguez, Carmen Mirabelli, Fatih Demir, Naziia Kurmasheva, Suresh K. Ramakrishnan, Madlen Kunke, Yifan Tan, et al.mouse anti-SARS-CoV-2 Nucleoprotein Antibody (ProSci, 35–579); sheep anti-N-Cadherin (R&D Systems, AF6426); rabbit anti-Megalin (Sigma, SAB1305050); mouse anti-SARS-CoV-2 spike (GeneTex, GTX632604); rabbit

(3) Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCsInternational journal of molecular sciencesJune 30, 2022Khadim RR, Vadivelu RK, Utami T, Torizal FG, Nishikawa M, Sakai Y.Santa Cruz Biotechnology), anti-E-cadherin (mouse, 10 µg/mL, MAB1838 R&D Systems), anti-N-cadherin (sheep, 10 µg/mL, AF6426 R&D Systems), anti-GATA6 (mouse, 10 µg/mL, MAB1700 R&D Systems), anti-Sox2 (mouse, 10 µg/ml, MAB2018

(4) Ym1⁺ macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic canceriScienceMay 20, 2022Fleming Martinez AK, Döppler HR, Bastea LI, Edenfield BH, Liou GY, Storz P.(clone EPR1791-4),Abcam,Cat# ab76011; RRID:AB_1310479 Sheep polyclonal anti-N-cadherin,R&D Systems,Cat# AF6426;RRID: AB_10718850 Rabbit polyclonal anti-Periostin,Abcam,Cat# ab14041; RRID:AB_2299859 Rabbit polyclonal

(5) Reciprocal interplay between asporin and decorin: Implications in gastric cancer prognosisPloS oneJanuary 1, 2021Basak D, Jamal Z, Ghosh A, Mondal PK, Dey Talukdar P, Ghosh S, Ghosh Roy B, Ghosh R, Halder A, Chowdhury A, et al.Minneapolis, USA), anti-E-cadherin (Cat# AF748, R & D Systems, Minneapolis, USA), anti-N-cadherin (Cat# AF6426, R & D Systems, Minneapolis, USA), anti-Fibronectin (Cat# ab2413, Abcam, Cambridge, MA, USA), anti-TGFβ1

(6) Specific Binding of Novel SPION-Based System Bearing Anti-N-Cadherin Antibodies to Prostate Tumor CellsInternational journal of nanomedicineJanuary 1, 2021Karnas K, Strączek T, Kapusta C, Lekka M, Dulińska-Litewka J, Karewicz A.Sigma-Aldrich, Poznań, Poland), Human/Mouse/Rat N-Cadherin Antibody (polyclonal sheep IgG, catalogue no. AF6426, R&D Systems), Donkey Anti-Sheep IgG NorthernLights™ NL557-conjugated Antibody (polyclonal donkey IgG,

(7) Synapse elimination activates a coordinated homeostatic presynaptic response in an autaptic circuitCommunications BiologyDecember 1, 2020Cecilia D. Velasco, Artur LlobetADI-VAM-PS003) combined with one of the following polyclonal antibodies: anti-N-cadherin (10 μg/ml, R&D Systems, AF6426), anti-VAMP-2 (1:500, Synaptic Systems, 104202), or, anti-Synapsin-I (1:1000, Millipore, AB1543P). Appropriate

(8) Induction of in vitro Metabolic Zonation in Primary Hepatocytes Requires Both Near-Physiological Oxygen Concentration and FluxFrontiers in Bioengineering and BiotechnologyJune 3, 2020Benedikt Scheidecker, Marie Shinohara, Masahiro Sugimoto, Mathieu Danoy, Masaki Nishikawa, Yasuyuki Sakai(1:200, ab49873, Abcam, UK); sheep anti-SLC2A1 (1:200, ab54263, Abcam, UK; sheep anti CDH2 (1:400, AF6426, R&D Systems, USA); rabbit anti-active β-catenin (1:800, D13A1, Cell Signaling, USA). After repeated

(9) Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathyEMBO molecular medicineFebruary 7, 2020Wu JH, Li YN, Chen AQ, Hong CD, Zhang CL, Wang HL, Zhou YF, Li PC, Wang Y, Mao L, et al.N‐cadherin (1:1,000, 33‐3900, Life Technologies), N‐cadherin (1:500, ab18203, Abcam), N‐cadherin (1:500, AF6426, R&D Systems), β‐catenin (1:500, #8480, Cell Signaling), β‐catenin (1:1,000, 51067‐2‐AP, Proteintech),

(10) ADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel DevelopmentScientific reportsOctober 1, 2019Ikeda A, Shahid S, Blumberg BR, Suzuki M, Bartlett JD.

(11) GSK3 regulates hair cell fate in the developing mammalian cochleaDevelopmental biologySeptember 15, 2019Ellis K, Driver EC, Okano T, Lemons A, Kelley MW.anti-S100A1 at 1:200 (R&D Systems. Cat. No. AF4138), Sheep anti-CDH2 at 1:500 (R&D Systems. Cat. No. AF6426), Mouse anti-CALB1 at 1:500 (Abcam Cat. No. 82812), Goat anti-NGFR at 1:500 (R&D Systems. Cat. No. AF367),

(12) Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistancePLoS computational biologyJune 1, 2019Su Y, Bintz M, Yang Y, Robert L, Ng AHC, Liu V, Ribas A, Heath JR, Wei W.antibody (BioLegend Cat# 345106 RRID:AB_2152647) or sheep polyclonal anti-N-Cadherin (R&D Systems Cat# AF6426 RRID:AB_10718850) was diluted to 0.25 or 10 μg/mL, respectively, in antibody diluent (1% BSA, 1% normal

(13) Organoid single cell profiling identifies a transcriptional signature of glomerular diseaseJCI insightJanuary 10, 2019Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, et al.

(14) Distinct roles of VE ‐cadherin for development and maintenance of specific lymph vessel bedsThe EMBO JournalNovember 15, 2018René Hägerling, Esther Hoppe, Cathrin Dierkes, Martin Stehling, Taija Makinen, Stefan Butz, Dietmar Vestweber, Friedemann KieferLyve-1 (clone ALY7) coupled to Alexa 488 (eBioscience), sheep polyclonal anti-mouse N-Cadherin (R&D Systems, AF6426), rabbit polyclonal anti-mouse ESAM1 [VE-19, (Nasdala et al, 2002)], rabbit polyclonal anti-mouse VE-cadherin

(15) MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytesFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJune 1, 2018Wan Y, Jin HJ, Zhu YY, Fang Z, Mao L, He Q, Xia YP, Li M, Li Y, Chen X, et al.

(16) Rab coupling protein mediated endosomal recycling of N-cadherin influences cell motilityOncotargetDecember 1, 2017Andrew J. Lindsay, Mary W. McCaffreyE-cadherin (goat S-17; Santa Cruz), N-cadherin (mouse clone 32; BD Biosciences), N-cadherin (sheep #AF6426; R&D Systems), N-cadherin (rabbit #ab18203; Abcam), Rab14 (rabbit #R0656; Sigma) and RCP (chicken #GW21574A;

(17) The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve RegenerationNeuronSeptember 27, 2017Clements MP, Byrne E, Camarillo Guerrero LF, Cattin AL, Zakka L, Ashraf A, Burden JJ, Khadayate S, Lloyd AC, Marguerat S, et al.N-cadherin,BD Biosciences,Cat# 610920 RRID: AB_2077527 Sheep polyclonal N-cadherin,R and D Systems,Cat# AF6426 RRID: AB_10718850 Goat polyclonal MBP (D-18),Santa Cruz Biotechnology,Cat# sc-13912 RRID: AB_648794 Chicken

(18) BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosisJournal of translational medicineSeptember 22, 2017Cherubini E, Mariotta S, Scozzi D, Mancini R, Osman G, D'Ascanio M, Bruno P, Cardillo G, Ricci A.

(19) MMP20 modulates cadherin expression in ameloblasts as enamel developsJournal of dental researchDecember 1, 2013Guan X, Bartlett JD.

(20) Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac gap junction maintenanceExperimental Cell ResearchAugust 15, 2013Takashi Sakurai, Mariko Tsuchida, Paul D. Lampe, Masahiro Murakamiunphosphorylated isoforms of Cx43 (Fred Hutchinson Cancer Research Center, Cx43CT1) [25], N-cadherin (R&D systems, AF6426), hemagglutinin (HA) (Covance, MMS-101P), β-tubulin (Sigma, T7816) and phosphorylated isoforms of Cx43

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N-Cadherin Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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N-Cadherin Antibody from R&D Systems, a Bio-Techne Brand

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