Fig 1: U2 auxiliary factor homology motif kinase 1 (UHMK1) activated the phosphoinositide 3‐kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway in lung adenocarcinoma cells. (a) Volcano plot analysis of our transcriptome data. (b) The heat map of the top 20 significantly upregulated and downregulated genes. (c) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of the transcriptome sequencing data. (d) Evaluation of the levels of proteins related to the PI3K/AKT/mTOR signaling pathway by western blotting assay.
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