Fig 2: Down-regulation of SOX11 impaired the protective effects of TsI on EA.hy926 cells exposed to DEX. EA.hy926 cells were transfected with siRNA against SOX11 or its negative control. Forty-eight hours after cell transfection, a, b qRT-PCR and Western blot were used to determine the expression of SOX11 in EA.hy926 cells. c, d Wound-healing and tube formation assays were performed to determine the migration capability and angiogenesis activity of EA.hy926 cells, respectively. e The mRNA level of CD31 was detected by qRT-PCR. Magnification 100 ×; scale bars: 200 μm. **P < 0.01. N = 3 in each group