InVivoMAb anti-mouse c-Kit (CD117) BE0293-R005mg from Bio X Cell

Product Specs
ItemInVivoMAb anti-mouse c-Kit (CD117)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0293-R005mg
Antibody TypePrimary Antibody
Targetc-Kit
CloneACK2
IsotypeIgG2b
Purity>95%, Determined by SDS-PAGE
Hostrat
ConcentrationLot specific,typically between 4-11 mg/ml
ClonalityMonoclonal
Quantity5 mg
Conjugate/TagUnconjugated
ImmunogenIL-3-dependent mast cells
Applicationsin vivo mast cell depletion, in vivo c-Kit+ cell depletion, in vitro c-Kit neutralization, Immunoprecipitation, Flow cytometry
ReactivityMouse
NCBI Full Gene NameKIT proto-oncogene receptor tyrosine kinase
NCBI Gene AliasesBs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaCancer Biology, Cytokine Receptor, Immunology, Tumor Antigens

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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(1) Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse modelOncotargetAugust 9, 2016Kuribayashi W, Takizawa K, Sugata K, Kuramitsu M, Momose H, Sasaki E, Hiradate Y, Furuhata K, Asada Y, Iwama A, et al.

(4) Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic miceProceedings of the National Academy of Sciences of the United States of AmericaDecember 2, 2008Louvet C, Szot GL, Lang J, Lee MR, Martinier N, Bollag G, Zhu S, Weiss A, Bluestone JA.

(5) Efficient transplantation via antibody-based clearance of hematopoietic stem cell nichesScience (New York, N.Y.)November 23, 2007Czechowicz A, Kraft D, Weissman IL, Bhattacharya D.

(6) The blood contains multiple distinct progenitor populations with clonogenic B and T lineage potentialJournal of immunology (Baltimore, Md. : 1950)April 1, 2007Umland O, Mwangi WN, Anderson BM, Walker JC, Petrie HT.

(8) Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit productThe Journal of clinical investigationOctober 1, 1993Furitsu T, Tsujimura T, Tono T, Ikeda H, Kitayama H, Koshimizu U, Sugahara H, Butterfield JH, Ashman LK, Kanayama Y.

(10) Role of c-kit in mouse spermatogenesis: identification of spermatogonia as a specific site of c-kit expression and functionDevelopment (Cambridge, England)October 1, 1991Yoshinaga K, Nishikawa S, Ogawa M, Hayashi S, Kunisada T, Fujimoto T, Nishikawa S.

InVivoMAb anti-mouse c-Kit (CD117)