Fig 1: Comparison of GABAergic neurons subtypes in WT vs. TLE. (A) Representative images of immunostaining of PV+ and SOM+ neurons in dDG of WT and TLE mice. Scale bar, 200 µm. (B) The densities of SOM+ and PV+ neurons in dDG/CA3 (SOM+: WT, n = 6 mice, TLE, n = 6 mice; PV+: WT, n = 6 mice, TLE, n = 5 mice). (C) Representative images of immunostaining of NTSR+, CCK+, and VIP+ neurons in dLS of WT and TLE mice. Scale bar, 200 µm. (D) The densities of NTSR+, CCK+, and VIP+ neurons in dLS (NTSR+: WT, n = 11 mice, TLE, n = 10 mice; CCK+: WT, n = 6 mice, TLE, n = 9 mice, VIP+: WT, n = 11 mice, TLE, n = 6 mice) (Error bars represent s.d; *p < 0.05; **p < 0.01, ***p < 0.001, t-test).
Fig 2: Parvalbumin (PV) interneurons and SOM interneurons were decreased with chronic inflammatory pain. Representative images of PV (A), SOM (B), NPY (C), and VIP (D) positive cells in the bilateral ACC in the control and model groups of rats. Quantification of the immunofluorescence results of PV (E), SOM (F), NPY (G), and VIP positive (H) cells in the ipsilateral and contralateral ACC in the control and model groups (whole figure scale bars: 500 µm; local figure scale bars: 50 µm). All data represent the mean ± SEM, n = 3/group. **P < 0.01 compared to the control group.
Supplier Page from Abcam for Anti-VIP antibody [EPR23288-43]