Fig 1: Effects of IQ on the HSP90-NlLRP3 pathway. (A) Protein expression of pro-IL1ß, cleaved-IL1ß, caspase-1 and cleaved-caspase-1 in the liver tissue of mice. (B) Protein expression of ASC and NLRP3 in the liver tissue of mice. (C) Protein expression of HSP90, HSF1, and SGT1 in the liver tissue of mice. (D) Molecular docking of IQ with HSF1 and (E) HSP90-SGT1. The bar indicates mean ± SD. * p < 0.05, ** p < 0.01, or *** p < 0.001 represents the significance of differences, and p < 0.05 is considered statistically significant. The significance is calculated using the Kruskal–Wallis test for the nonparametric test.