Fig 1: The mechanism of UTX in the tumor progression. (a) Balance of H3K27 methylation between UTX and EZH2 function in the tumor cell transcription; (b) Loss of UTX induces increased H3K27 methylation, leading to inhibition of tumor cell transcription
Fig 2: Results of the immunohistochemical analysis of UTX in oral tongue squamous cell carcinoma patients
Fig 3: Western blot analysis of UTX expression and the downstream signaling pathway in the SAS and Cal 27 cell lines. The protein expression profiles of UTX, H3K27me3 status, EMT markers, cyclin D1 and CDK4 were examined in the presence or absence of GSK-J4 treatment in the OTSCC cells by Western blotting
Fig 4: Comparison of Kaplan-Meier curves in oral tongue squamous cell carcinoma patients with high and low expression of UTX. (a) Disease-free survival (b) Overall survival
Supplier Page from Abcam for Anti-KDM6A / UTX antibody