Fig 1: Functional analysis of YTHDF2-interacting proteins in cardiomyocytes stimulated with ISO. (A and B) GO (A) and KEGG (B) annotation enrichment analysis of the YTHDF2 interacting proteins identified by mass spectrometry using Metascape (https://metascape.org). C Protein–protein interaction (PPI) network analysis of the YTHDF2 interacting proteins by Cytoscape. D Transcriptional factor analysis of the YTHDF2 interacting proteins. E Co-IP analysis of the interaction between YTHDF2 and MYH7/SRF/BRCA1 in the cardiomyocytes stimulated with ISO (10 μmol/l) or DMSO (as control). F RIP analysis of the interaction between YTHDF2 and SRF/BRCA1 mRNA in the cardiomyocytes stimulated with ISO (10 μmol/l) or DMSO (as control). *P < 0.05