Fig 1: Farrerol inhibits Ang II-induced cardiac remodeling in vitro. (A) Representative images of Myocardial cells stained with a-actinin in each group and the relative value of the statistical chart; (B) Mitochondrial ROS levels in NRVMs were determined by MitoSOX Red staining; (C) The expression of p-AKT (Ser473), AKT, NOX2 and ß-actin detected by Western Blot; (D) The expression of p-ERK 1/2, ERK 1/2, p-STAT3, STAT3, NFAT2 and ß-actin detected by Western Blot; (E) the migration ability of fibroblasts by Wound scratch assay in each group; (F) The proliferation ability of fibroblasts was detected by CCK-8; (G) The expression of p-AKT (Ser473), AKT, NOX2 and ß-actin detected by Western Blot (Salline = 3, Farrerol = 3, Ang II = 3, Ang II + Farrerol = 3).