Integrin alpha 6/CD49f Antibody MAB13501 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIntegrin alpha 6/CD49f Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB13501
NCBI Gene AliasesCD49f, ITGA6A, ITGA6B, JEB6, VLA-6
ApplicationsFlow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-reported
ReactivityHuman, Mouse, Bovine
TargetIntegrin alpha 6/CD49f
IsotypeIgG2a
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
HostRat
CloneGoH3
NCBI Full Gene Nameintegrin subunit alpha 6
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse mammary tumor cells
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Apoptosis recognition receptors regulate skin tissue repair in miceElifeDecember 21, 2023Olivia Justynski, Kate Bridges, Will Krause, Maria Fernanda Forni, Quan M Phan, Teresa Sandoval-Schaefer, Kristyn Carter, Diane E King, Henry C Hsia, Michael I Gazes, et al.R&D Systems Cat# AB-108-C, RRID:AB_354267IgG: Bio X Cell Cat# BE0290, RRID:AB_2687813ITGA6: R&D Systems Cat# MAB13501, RRID:AB_2128311Lyve1: Abcam Cat# ab14917, RRID:AB_301509Timd4: Thermo Fisher Scientific Cat# PA5-116045,

(2) Heterogeneity of Phase II Enzyme Ligands on Controlling the Progression of Human Gastric Cancer Organoids as Stem Cell Therapy ModelInternational Journal of Molecular SciencesNovember 2, 2023Deng-Chyang Wu, Chia-Chen Ku, Jia-Bin Pan, Kenly Wuputra, Ya-Han Yang, Chung-Jung Liu, Yi-Chang Liu, Kohsuke Kato, Shigeo Saito, Ying-Chu Lin, et al.actin (α-SMA; 1:50; #E14344; Spring Bioscience Corporation, Pleasanton, CA, USA), integrin α6 (1:50; #MAB13501; R&D systems, Minneapolis, MN, USA), NRF2 (1:50; #BS1258; Bioworld Technology, Cambridge, UK), AHR (1:50;

(3) An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal PhenotypeCancers (Basel)October 12, 2023Natalia Vydra, Agnieszka Toma-Jonik, Patryk Janus, Katarzyna Mrowiec, Tomasz Stokowy, Magdalena Głowala-Kosińska, Damian Robert Sojka, Magdalena Olbryt, Wiesława Widłakfor 1 h at room temperature. Cells were incubated with rat monoclonal antibody against ITGA6 (1:50, MAB13501, R&D Systems, MN, USA) or rabbit monoclonal antibody against CDH1 (1:100, #3195, Cell Signaling Technology)

(4) The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formationiScienceMay 19, 2023Jian Song, Tushar Deshpande, Xueli Zhang, Melanie-Jane Hannocks, Nils Lycke, Susanna L. Cardell, Lydia Sorokinet al.47,Clone 3E10 Laminin γ3,Li et al.21,Antibody R96 Lntegrin α6,R&D Systems,Clone GoH3; Cat # MAB13501; RRID: AB_2128311 B220,R&D Systems,"Clone RA3-6B2, Cat # MAB1217; RRID: AB_357537" CD11b/MAC-1,R&D Systems

(5) 3D bioprinting of an implantable xeno‐free vascularized human skin graftBioengineering & Translational MedicineJanuary 1, 2023Tania Baltazar, Bo Jiang, Alejandra Moncayo, Jonathan Merola, Mohammad Z. Albanna, W. Mark Saltzman, Jordan S. Poberintegrins α2β1 (ab24697; abcam), α5β1 (NBP2‐52680; Novus Biologics), αvβ3 (sc‐7312; Santa Cruz), α6 (MAB13501; R&D systems), α3 (MAB1345; R&D systems), β4 (NBP1‐43369), CK14 (LL002; Novus Biologics), CK10 (EP1607IHCY,

(6) Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosisNature communicationsJuly 25, 2022Bae E, Huang P, Müller-Greven G, Hambardzumyan D, Sloan AE, Nowacki AS, Marko N, Carlin CR, Gladson CL.anti-integrin α3 subunit (EMD Millipore, MAB1952P, clone P1B5), rat anti-integrin α6 subunit (R&D systems, MAB13501, clone GoH3), and mouse mAb anti-CD151 (clone 1A5, a kind gift from Dr. Andries Zijlstra and Dr. James

(7) Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term cultureScientific reportsJune 30, 2022Ouji Y, Misu M, Kitamura T, Okuzaki D, Yoshikawa M.

(8) Mechanosensitive collaboration between integrins and connexins allows nutrient and antioxidant transport into the lensThe Journal of cell biologyDecember 7, 2020Liu J, Riquelme MA, Li Z, Li Y, Tong Y, Quan Y, Pei C, Gu S, Jiang JX.al., 1994). Rat integrin α6 functional blocking antibody (10 µg/ml) was obtained from R&D Systems (MAB13501; Primo et al., 2010). Mouse anti-chicken integrin α6 for Western blot was obtained from the Developmental

(9) Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by ProteomicsMolecular & cellular proteomics : MCPJuly 1, 2020Béguin EP, Janssen EFJ, Hoogenboezem M, Meijer AB, Hoogendijk AJ, van den Biggelaar M.package. The following antibodies were used: Rat IgG2b α ITGB4 555719 (BD Biosciences); Rat IgG2a α ITGA6 MAB13501 & Sheep polyclonal α LAMA4 AF7340 (R&D systems); Rabbit IgG polyclonal α FBLN2 PA5–51665 (Thermo Scientific);

(10) Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin RepairCell stem cellJune 4, 2020Shook BA, Wasko RR, Mano O, Rutenberg-Schoenberg M, Rudolph MC, Zirak B, Rivera-Gonzalez GC, López-Giráldez F, Zarini S, Rezza A, et al.,BD Bioscience,Cat# 550274 RRID: AB_393571 Anti-mouse ITGA6 rat monoclonal (clone GoH3),R&D Systems,Cat# MAB13501 RRID: AB_2128311 Anti-ER-TR7 rat monoclonal,Abcam,Cat# ab51824 RRID: AB_881651 Anti-GFP chicken polyclonal,Abcam,Cat#

(11) Phenotypic Analysis of BrdU Label-Retaining Cells during the Maturation of Conducting Airway Epithelium in a Porcine LungStem cells internationalJanuary 1, 2019Jia Y, You X, Ma N, Li H, Liu G, Wang Y, Xue J, Shi J, Wei J, Li Y, et al.

(12) Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signalingStem cell researchDecember 1, 2018Weng NJ, Cheung C, Talbot P.

(13) RANK Signaling Blockade Reduces Breast Cancer Recurrence by Inducing Tumor Cell DifferentiationCancer researchOctober 1, 2016Yoldi G, Pellegrini P, Trinidad EM, Cordero A, Gomez-Miragaya J, Serra-Musach J, Dougall WC, Muñoz P, Pujana MA, Planelles L, et al.

(14) Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinomaOncotargetMay 3, 2016Unruh D, Ünlü B, Lewis CS, Qi X, Chu Z, Sturm R, Keil R, Ahmad SA, Sovershaev T, Adam M, et al.

(15) Endothelial podosome rosettes regulate vascular branching in tumour angiogenesisNature cell biologyOctober 1, 2014Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, et al.

(16) Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrinThe Journal of biological chemistryJuly 11, 2014Samarelli AV, Riccitelli E, Bizzozero L, Silveira TN, Seano G, Pergolizzi M, Vitagliano G, Cascone I, Carpentier G, Bottos A, et al.

(17) Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-lamininsMatrix biology : journal of the International Society for Matrix BiologyJune 1, 2014Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I, Patarroyo M.

(18) α6-Integrin is required for the adhesion and vasculogenic potential of hemangioma stem cellsStem CellsMarch 1, 2014Smadja DM, Guerin CL, Boscolo E, Bieche I, Mulliken JB, Bischoff J.

(19) A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopyThe EMBO journalMarch 6, 2013Hägerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams RH, Alitalo K, Andresen V, Schulte-Merker S, Kiefer F.anti-mouse Podoplanin (clone 8.1.1, in-house made), rat monoclonal anti-human Integrin α6 (GoH3, R&D, MAB13501), rabbit polyclonal anti-mouse Lyve-1 (ReliaTech, 103-PA50), goat polyclonal anti-human Neuropilin-2

(20) CD98hc (SLC3A2) regulation of skin homeostasis wanes with ageThe Journal of experimental medicineJanuary 14, 2013Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, Meneguzzi G, Féral CC.

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Integrin alpha 6/CD49f Antibody from R&D Systems, a Bio-Techne Brand

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Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (24)

Reviews

Integrin alpha 6/CD49f Antibody from R&D Systems, a Bio-Techne Brand

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