Fc gamma RIII (CD16) Antibody MAB19601 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFc gamma RIII (CD16) Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB19601
NCBI Gene AliasesCD16
ApplicationsFlow Cytometry, CyTOF-ready
Clone275003
HostRat
IsotypeIgG2a
Conjugate/TagUnconjugated
ReactivityMouse
TargetFc gamma RIII (CD16)
Quantity100 ug (also 25 ug)
NCBI Full Gene NameFc receptor, IgG, low affinity III
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse Fc gamma RIII, Ala31-Thr215, Accession # Q5D5J5
ConcentrationLYOPH
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse Fc gamma RIIIA/B (CD16) in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Fcrl3/CD16-2, rmFc gamma RIA or rhFc gamma RIIA is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed jointsProceedings of the National Academy of Sciences of the United States of AmericaFebruary 11, 2020Panda SK, Wigerblad G, Jiang L, Jiménez-Andrade Y, Iyer VS, Shen Y, Boddul SV, Guerreiro-Cacais AO, Raposo B, Kasza Z, et al.

(2) Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor ActivityCell reportsJune 11, 2019Zhang P, Tu GH, Wei J, Santiago P, Larrabee LR, Liao-Chan S, Mistry T, Chu ML, Sai T, Lindquist K, et al.

(3) Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunityJournal of neuroinflammationFebruary 26, 2019Ott M, Avendaño-Guzmán E, Ullrich E, Dreyer C, Strauss J, Harden M, Schön M, Schön MP, Bernhardt G, Stadelmann C, et al.

(4) A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritisNature immunologyFebruary 1, 2019Arandjelovic S, Perry JSA, Lucas CD, Penberthy KK, Kim TH, Zhou M, Rosen DA, Chuang TY, Bettina AM, Shankman LS, et al.

(5) HoxB8 neutrophils replicate Fcγ receptor and integrin-induced neutrophil signaling and functionsJournal of leukocyte biologyJanuary 1, 2019Chu JY, McCormick B, Mazelyte G, Michael M, Vermeren S.

(6) C5aR activation in the absence of C5a: A new disease mechanism of autoimmune hemolytic anemia in miceEuropean journal of immunologyApril 1, 2018Syed SN, Rau E, Ziegelmann M, Sogkas G, Brüne B, Schmidt RE.

(7) DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivoThe Journal of experimental medicineMay 1, 2017Lehmann CHK, Baranska A, Heidkamp GF, Heger L, Neubert K, Lühr JJ, Hoffmann A, Reimer KC, Brückner C, Beck S, et al.

(8) IgG subclasses determine pathways of anaphylaxis in miceThe Journal of allergy and clinical immunologyJanuary 1, 2017Beutier H, Gillis CM, Iannascoli B, Godon O, England P, Sibilano R, Reber LL, Galli SJ, Cragg MS, Van Rooijen N, et al.

(9) Rapid desensitization of mice with anti-FcγRIIb/FcγRIII mAb safely prevents IgG-mediated anaphylaxisThe Journal of allergy and clinical immunologyDecember 1, 2013Khodoun MV, Kucuk ZY, Strait RT, Krishnamurthy D, Janek K, Clay CD, Morris SC, Finkelman FD.

(10) Cutting edge: FcγRIII (CD16) and FcγRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanomaJournal of immunology (Baltimore, Md. : 1950)December 15, 2012Albanesi M, Mancardi DA, Macdonald LE, Iannascoli B, Zitvogel L, Murphy AJ, Daëron M, Leusen JH, Bruhns P.

(11) Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCsJournal of leukocyte biologyDecember 1, 2011Kool M, Geurtsvankessel C, Muskens F, Madeira FB, van Nimwegen M, Kuipers H, Thielemans K, Hoogsteden HC, Hammad H, Lambrecht BN.

(12) Mouse and human neutrophils induce anaphylaxisThe Journal of clinical investigationApril 1, 2011Jönsson F, Mancardi DA, Kita Y, Karasuyama H, Iannascoli B, Van Rooijen N, Shimizu T, Daëron M, Bruhns P.

(13) β5 integrin is the major contributor to the αVintegrin-mediated blockade of HIV-1 replicationJournal of immunology (Baltimore, Md. : 1950)January 1, 2011Ballana E, Pauls E, Clotet B, Perron-Sierra F, Tucker GC, Esté JA.

(14) Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5aEuropean journal of immunologyDecember 1, 2009Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE.

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Fc gamma RIII (CD16) Antibody

Fc gamma RIII (CD16) Antibody

Fc gamma RIII (CD16) Antibody

Fc gamma RIII (CD16) Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (14)

Reviews

Fc gamma RIII (CD16) Antibody from R&D Systems, a Bio-Techne Brand

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