Anti-PSD95 antibody - Synaptic Marker ab18258 from Abcam

Product Specs
ItemAnti-PSD95 antibody - Synaptic Marker
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab18258
Antibody TypePrimary
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Quantity100 UG
Conjugate/TagUnconjugated
Concentration0.5 mg/ml
Gene NameDLG4
ReactivityHuman, Mouse, Rat
TargetPSD95

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Enhanced TARP-γ8-PSD-95 coupling in excitatory neurons contributes to the rapid antidepressant-like action of ketamine in male miceNat CommunDecember 2, 2023Shi-Ge Xue, Jin-Gang He, Ling-Li Lu, Shi-Jie Song, Mei-Mei Chen, Fang Wang, Jian-Guo ChenCambridge, UK), β-actin (1:3000; sc-47778, Santa Cruz Biotechnology, Santa Cruz, CA), PSD-95 (1:1000; ab18258, Abcam, Cambridge, UK), CaMKIIα (1:800; 50049, Cell Signaling, USA), Phospho-CaMKII (1:800; 12716, Cell Signaling

(2) Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampusAging (Albany NY)November 25, 2023Hyo Young Jung, Hyun Jung Kwon, Kyu Ri Hahn, Woosuk Kim, Dae Young Yoo, Yeo Sung Yoon, Dae Won Kim, In Koo Hwanganti-NMDAR1 (1:1000, Cat# 5704, Cell Signaling, Danvers, MA, USA), rabbit anti-PSD95 (1:1000, Cat# ab18258, Abcam), rabbit anti-VGLUT2 (1:5000, Cat# ab79157, Abcam), mouse anti-P16 (1:500; Cat#sc-377412, Santa Cruz Biotechnology

(3) Engineering memory with an extrinsically disordered kinaseScience AdvancesNovember 17, 2023Cristian Ripoli, Onur Dagliyan, Pietro Renna, Francesco Pastore, Fabiola Paciello, Raimondo Sollazzo, Marco Rinaudo, Martina Battistoni, Sara Martini, Antonella Tramutola, et al.from Sigma-Aldrich. Myc antibody (clone 4A6, #05-724) was purchased from Sigma-Aldrich. Anti-PSD95 (#ab18258) and anti-actin (ab8227) antibodies were purchased from Abcam. Molecular cloning and protein structures Point

(4) MEX3C induces cognitive impairment in mice through autophagy inhibitionBrain and BehaviorNovember 1, 2023Kai Wang, Hao‐Nan Zhang, Yong Du5% BSA at room temperature (RT) (25°C) RT for 1 h. NeuN (ab177487, Abcam; dilution, 1:1000); PSD95 (ab18258, Abcam; dilution, 1:1000); GAP‐43 (ab75810, Abcam; dilution, 1:1000); p62 (GB11531, Servicebio; dilution,

(5) Autoimmune receptor encephalitis in ApoE‑/‑ mice induced by active immunization with NMDA1Molecular Medicine ReportsOctober 30, 2023Liming Yu, Yujun Wen, Juan Yang, Guowei Wang, Na Zhang, Xinlei Gao, Jiayu Guo, Zhenhai WangNMDA1 (1:1,000; cat. no. ab134308; Abcam), postsynaptic density protein 95 (PSD-95; 1:1,000; cat. no. ab18258; Abcam) and GAPDH antibodies (1:1,000; cat. no. TA802519; OriGene Technologies, Inc.) overnight at 4°C.

(6) High-throughput single-cell analysis reveals progressive mitochondrial DNA mosaicism throughout lifeScience AdvancesOctober 27, 2023Angelos Glynos, Lyuba V. Bozhilova, Michele Frison, Stephen Burr, James B. Stewart, Patrick F. Chinnerysamples were stained with GLAST (ACSA-1)–PE (Miltenyi Biotech, PN: 130-118-344) and PSD95 (Abcam, PN: ab18258) used alongside the secondary antibody Briliant Violet 421 (BioLegend, 406410). Mouse spleen samples

(7) α-Synuclein propagation leads to synaptic abnormalities in the cortex through microglial synapse phagocytosisMolecular BrainOctober 17, 2023Dayana Pérez-Acuña, Soo Jean Shin, Ka Hyun Rhee, Sang Jeong Kim, Seung-Jae LeeX-100 for 4 h at room temperature. Slices were then incubated with primary antibodies against PSD95 (ab18258 or ab12093, 1:500: Abcam); Vglut1 (135304; Synaptic Systems, Goettingen, Germany), or pS129-α-syn (clone

(8) Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged miceStem Cell Research & TherapySeptember 21, 2023Penghui Wei, Min Jia, Xiangyi Kong, Wenyuan Lyu, Hao Feng, Xinyi Sun, Jianjun Li, Jian-jun YangSanta Cruz Biotechnology, sc-271390), rabbit anti-PSD95 (postsynaptic density protein 95, 1:200, Abcam, ab18258), rabbit anti-synaptophysin (1:1000, Abcam, ab32127), and rabbit anti-CREB (phosphor S133, 1:100, Abcam,

(9) ApoE4 exacerbates the senescence of hippocampal neurons and spatial cognitive impairment by downregulating acetyl‐CoA levelAging CellSeptember 1, 2023Shuixin Lv, Yusi Zhang, Yingbin Lin, Wenting Fang, Yu Wang, Zihang Li, Anlan Lin, Xiaoman Dai, Qinyong Ye, Jing Zhang, et al.USA), VGLUT1 (1:1000, ab134283; Abcam, UK), synaptophysin (1:2000, ab32127; Abcam, UK), PSD95 (1:1000, ab18258; Abcam, UK), NR2B (1:1000, ab254356; Abcam, UK), NR2A (1:1000, ab124913; Abcam, UK), β‐actin (1:1000,

(10) Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerabilitybioRxivAugust 7, 2023Richard Drexler, Robin Khatri, Thomas Sauvigny, Malte Mohme, Cecile L. Maire, Alice Ryba, Yahya Zghaibeh, Lasse Dührsen, Amanda Salviano-Silva, Katrin Lamszus, et al.(1:500; Synaptic Systems), chicken anti-neurofilament (M+H; 1:1000; Aves Labs) or PSD95 (1:500, Abcam ab18258), were diluted in antibody diluent solution (1% normal donkey serum in 0.3% Triton X-100 in TBS) and

(11) Inhibition of hippocampal cyclin‐dependent kinase 5 activity ameliorates learning and memory dysfunction in a mouse model of bronchopulmonary dysplasiaCNS Neuroscience & TherapeuticsAugust 1, 2023Fang‐Fei Tao, Zi‐Yu Wang, Ying Wang, Qian‐Ru Lv, Peng‐Peng Cai, Hai‐Wen Min, Jian‐Wei Ge, Chun‐Yu Yin, Rui Chengat 4°C with the following primary antibodies: anti‐CDK5 (ab40773, Abcam, rabbit, 1:200), anti‐PSD95 (ab18258, Abcam, rabbit, 1:200), and anti‐NeuN (ab104224, Abcam, mouse, 1:200). The next day, the primary antibody‐incubated

(12) Epigenetically distinct synaptic architecture in clonal compartments in the teleostean dorsal palliumeLifeJuly 25, 2023Yasuko Isoe, Ryohei Nakamura, Shigenori Nonaka, Yasuhiro Kamei, Teruhiro Okuyama, Naoyuki Yamamoto, Hideaki Takeuchi, Hiroyuki TakedaG5163], and GAD 67 [Sigma G5038], 1:2000 each), synapsin (Synaptic Systems, 106 011), and PSD (Abcam, ab18258) in 1% BSA/DMSO/Triton-X1000/PBS. Though we also tried anti-GAD 65 so far, we could not find the difference

(13) Scopolamine causes delirium-like brain network dysfunction and reversible cognitive impairment without neuronal lossZoological ResearchJuly 18, 2023Qing Wang, 四川大学华西医院国家老年医学临床研究中心老年医学科, 生物治疗国家重点实验室, 四川成都 610041, 中国, Department of Geriatrics and State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China, Xiang Zhang, Yu-Jie Guo, Ya-Yan Pang, Jun-Jie Li, Yan-Li Zhao, Jun-Fen Wei, Bai-Ting Zhu, et al.following antibodies were used (diluted in 0.02 mol/L TBST, pH 8.0): 1:1 000 for anti-PSD95 (Abcam, USA, ab18258); 1:1 000 for anti-synaptophysin (Millipore, USA, MAB5258-I); 1:1 000 for anti-GluR1 (Sigma-Aldrich,

(14) Temporary alteration of neuronal network communication is a protective response to redox imbalance that requires GPI-anchored prion proteinRedox biologyJuly 1, 2023Foliaki ST, Wood A, Williams K, Smith A, Walters RO, Baune C, Groveman BR, Haigh CL.(Sigma),1:200,Anti-Rabbit Alexa Fluor 647,1:500,IF Alexa Fluor 488 Phalloidin,A12379 (Invitrogen),1:500,–,–,IF PSD95,Ab18258 (Abcam),1:5000,Anti-Rabbit HRP,1:5000,WB Anti-DMPO,Ab104902 (Abcam),1:200,Anti-mouse Alexa Fluor 647,1:500,IF MAP2,188006

(15) MiR-431 attenuates synaptic plasticity and memory deficits in APPswe/PS1dE9 miceJCI insightJune 22, 2023Ge J, Xue Z, Shu S, Yu L, Qin R, Tao W, Liu P, Dong X, Lan Z, Bao X, et al.ab184955), rabbit anti-CaMKII (1:1,000, Abcam, catalog ab52476), rabbit anti–PSD-95 (1:1,000, Abcam, catalog ab18258), rabbit anti-synaptophysin (1:20,000, Abcam, catalog ab32127), and rabbit anti-GAPDH (1:5,000, Bioworld,

(16) Postoperative risk of IDH mutant glioma–associated seizures and their potential management with IDH mutant inhibitorsJournal of Clinical InvestigationJune 15, 2023Michael R. Drumm, Wenxia Wang, Thomas K. Sears, Kirsten Bell-Burdett, Rodrigo Javier, Kristen Y. Cotton, Brynna T Webb, Kayla T Byrne, Dusten Unruh, Vineeth Thirunavu, et al.Ser235/236, 2211; 1:1,000), synaptophysin (Thermo Fisher Scientific, SY38, MA1-213; 1:200), PSD95 (Abcam, ab18258; 1:200), ALDH1L1 (Abcam, ab177463; 1:500). Secondary immunofluorescent antibodies were used at 1:250

(17) Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivoFrontiers in PharmacologyJune 13, 2023Shuyuan Guan, Lingbin Sun, Xihua Wang, Xirui Huang, Tao Luoanti-NeuN: 1:200, ab104224; rabbit anti mouse PFKFB3: 1:200, ab181861; rabbit anti mouse PSD-95: 1:200; ab18258, Abcam, United States) at 4°C overnight followed by secondary antibodies (Alexa Fluor 594-labeled goat

(18) Selective Inhibition of Soluble Tumor Necrosis Factor Alters the Neuroinflammatory Response following Moderate Spinal Cord Injury in MiceBiologyJune 12, 2023Lund MC, Ellman DG, Nielsen PV, Raffaele S, Fumagalli M, Guzman R, Degn M, Brambilla R, Meyer M, Clausen BH, et al.manufacturer’s instructions. Primary antibodies used were rabbit anti-PSD95 (1:100, Abcam, cat. no. ab18258, Cambridge, United Kingdom), rat anti-MBP (1:50, Merck, cat. no MAB386, Søborg, Denmark), and α-actin

(19) Maternal Diabetes Deregulates the Expression of Mecp2 via miR-26b-5p in Mouse Embryonic Neural Stem CellsCellsMay 30, 2023Sukanya Shyamasundar, Seshadri Ramya, Deepika Kandilya, Dinesh Kumar Srinivasan, Boon Huat Bay, Suraiya Anjum Ansari, S Thameem DheenPrimary antibodies rabbit anti-Mecp2 (1:1000, ab2829, Abcam, Cambridge, UK), rabbit anti-PSD-95 (1:1000, ab18258, Abcam, Cambridge, UK), rabbit anti-Synaptophysin (1:1000, ab32127, Abcam, Cambridge, UK), mouse anti-tau

(20) High-Fat Diet Consumption Induces Neurobehavioral Abnormalities and Neuronal Morphological Alterations Accompanied by Excessive Microglial Activation in the Medial Prefrontal Cortex in Adolescent MiceInternational Journal of Molecular SciencesMay 28, 2023Conghui Wang, Hong Li, Chen Chen, Xiuting Yao, Chenxi Yang, Zhehao Yu, Jiayi Ren, Yue Ming, Yi Huang, Yi Rong, et al.goat anti-Iba1 (1:600, 011–27991; Wako), and rabbit anti-PSD95 (for the postsynaptic element, 1:1000, ab18258; Abcam, Cambridge, UK). After washing three times with PBS, the sections were incubated with the following

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7/13/2017Excellent For Paraffin Embedded Mouse Brain Tissues Kaveri AroraWe wanted to determine any changes in levels of PSD-95 in mouse hippocampus. We performed electrophysiology, particularly long term potentiation (LTP), and behavior studies on our KO mouse and ... Read Review

Anti-PSD95 antibody - Synaptic Marker from Abcam

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Anti-PSD95 antibody - Synaptic Marker from Abcam

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