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Antibodies
Anti-MDM2 antibody [2A10]
Anti-MDM2 antibody [2A10] from Abcam
Be the first to write a review!
Citations:
(96)
Supplier Page
Supplier Page from
Abcam for
Anti-MDM2 antibody [2A10]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-MDM2 antibody [2A10]
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab16895
Antibody Type
Primary
Clonality
Monoclonal
Clone
2A10
Host
Mouse, Nude mouse
Quantity
50 UG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Isotype
IgG2a
Conjugate/Tag
Unconjugated
Concentration
0.1 mg/ml
Gene Name
MDM2
Reactivity
Human
Target
MDM2
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (96)
(1)
A CRISPR-Cas9 library screening identifies CARM1 as a critical inhibitor of ferroptosis in hepatocellular carcinoma cells
Molecular Therapy - Nucleic Acids
December 12, 2023
Yiming Cheng, Xiaochen Wang, Shuyu Huang, Liang Zhang, Bei Lan, Xuanyuan Li, Hao Chen, Zhenfeng Liu, Yijie Su, Lishan Xi,
et al.
using the
mycoplasma
detection kit (D101, Vazamy, Nanjing, China). Anti-
GPX4
(
ab125066
), anti-MDM2 (
ab16895
) and anti-H3 (asymmetric di methyl R26) (
ab194679
) were purchased from
Abcam
Inc. (Cambridge, MA). Anti-β-actin
(2)
The Molecular Basis for Selectivity of the Cytotoxic Response of Lung Adenocarcinoma Cells to Cold Atmospheric Plasma
Biomolecules
November 20, 2023
Mikhail Biryukov, Dmitriy Semenov, Nadezhda Kryachkova, Alina Polyakova, Ekaterina Patrakova, Olga Troitskaya, Elena Milakhina, Julia Poletaeva, Pavel Gugin, Elena Ryabchikova,
et al.
(
ab125066
); anti-GPX7 (
ab96257
); anti-
ATF3
(
ab233797
),
anti-GADD45B
(
ab205252
), γH2AFX (
ab26350
) and MDM2 (
ab16895
) (
Abcam
, Cambridge, UK), anti-β-Tubulin (
T8328
,
Sigma-Aldrich
, St. Louis, MO, USA); and goat anti-rabbit
(3)
Deltonin enhances gastric carcinoma cell apoptosis and chemosensitivity to cisplatin via inhibiting PI3K/AKT/mTOR and MAPK signaling
World Journal of Gastrointestinal Oncology
October 15, 2023
Lin Yang, Ya-Nan Liu, Yi Gu, Qi Guo
(
ab32503
), anti-Bid (
ab32060
), anti-Bak (
ab32371
), anti-
Fas
(
ab133619
), anti-
Rad51
(
ab133534
), anti-MDM2 (
ab16895
), anti-PI3K (
ab32089
), anti-
mTOR
(
ab134903
), anti-p-mTOR (ab137133), anti-p-PI3K (ab182651), anti-AKT
(4)
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis
Redox biology
June 1, 2023
Gan Y, Deng J, Hao Q, Huang Y, Han T, Xu JG, Zhao M, Yao L, Xu Y, Xiong J,
et al
.
Signalway Antibody
), anti-
p53
(Cat. No.
sc-126
, DO-1,
Santa Cruz Biotechnology
), anti-MDM2 (Cat. No.
ab16895
, 2A10,
Abcam
), anti-
GAPDH
(Cat. No.
60004-1-Ig
,
Proteintech
), anti-RPL5 (Cat. No.
ab86863
,
Abcam
), anti-RPL11
(5)
Anticancer effect of involucrasin A on colorectal cancer cells by modulating the Akt/MDM2/p53 pathway
Oncology Letters
April 12, 2023
Chengming Wei, Jingjing Du, Yunfu Shen, Zi Wang, Qianyu Lin, Junhe Chen, Fuming Zhang, Wanjun Lin, Zhibin Wang, Zhuya Yang,
et al.
Santa Cruz Biotechnology, Inc
.); anti-p-
MDM2
(cat. no.
ab170880
; rabbit monoclonal) and anti-
MDM2
(cat. no.
ab16895
;
mouse
monoclonal) (both from
Abcam
). The anti-rabbit (cat. no.
211-035-109
) and anti-
mouse
(cat. no.
(6)
Quercetin Induces Apoptosis in HepG2 Cells via Directly Interacting with YY1 to Disrupt YY1-p53 Interaction
Metabolites
February 3, 2023
Hui Guan, Wenyuan Zhang, Hui Liu, Yang Jiang, Feng Li, Maoyu Wu, Geoffrey I. N. Waterhouse, Dongxiao Sun-Waterhouse, Dapeng Li
(
ab109237
,
1:5000
,
Abcam
, Waltham, MA, USA), p53 (
ab32389
,
1:10000
,
Abcam
, Cambridge, MA, USA), HDM2 (
ab16895
,
1:500
,
Abcam
, USA),
Bcl-2
(
ab196495
,
1:500
,
Abcam
, USA),
Bax
(
ab182733
,
1:2000
,
Abcam
, Cambridge, MA,
(7)
RPL15 promotes hepatocellular carcinoma progression via regulation of RPs-MDM2-p53 signaling pathway
Cancer Cell International
December 1, 2022
Rui Shi, Zirong Liu
p21
(
1:3000
;
Abcam
,
ab188224
, MA, USA), p53 (
1:1000
;
Abcam
,
ab32049
, MA, USA), MDM2 (
1:1000
;
Abcam
,
ab16895
, MA, USA), RPL5 (1 ug/ml;
Abcam
,
ab86863
, MA, USA), RPL11 (
1:3000
;
Abcam
,
ab79352
, MA, USA) overnight
(8)
Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice
Frontiers in Aging Neuroscience
November 8, 2022
Xiaoxuan Yang, Chen Chen, Dongmei Qu, Yanping Liu, Ning Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue,
et al.
FBXO22 antibody
(
Abcam
Cat#
ab230395
, United States, Rabbit polyclonal), NMDAR1 antibody (
Abcam
Cat#
ab16895
, United States, Mouse monoclonal), PSD-95 antibody (
1:000
,
CST
Cat#
3450S
, United States, Rabbit polyclonal),
(9)
Immunohistochemical Detection and Prognostic Significance of p53, Epidermal Growth Factor Receptor, Murine Double Minute 2, and Isocitrate Dehydrogenase 1 in Glioblastoma Multiforme Patients of Pakistan
Clinical Medicine Insights: Oncology
August 22, 2022
Syed Muhammad Adnan Ali, Muhammad Shahzad Shamim, Syed Ather Enam, Zubair Ahmad, Yumna Adnan, Hasnain Ahmed Farooqui
rabbit polyclonal IDH1 (
Abcam
,
ab81653
;
1:200
dilution), and
mouse
monoclonal MDM2 (
Abcam
,
clone
2A10,
ab16895
;
1:100
dilution). Afterwards, these sections were treated with secondary antibody EnVision FLEX +
Mouse
(10)
The circular RNA hsa_circ_0001394 promotes hepatocellular carcinoma progression by targeting the miR-527/UBE2A axis
Cell Death Discovery
February 24, 2022
Yu Yan, Yu Nie, Chun Peng, Fuchen Xing, Saiguang Ji, Hong Liu, Chuandong Zhu
anti-vimentin (
Abcam
, #
ab92547
,
1:1000
), anti-snail (
Abcam
, #
ab216347
,
1:1000
), anti-MDM2 (
Abcam
, #
ab16895
,
1:1000
), anti-p53 (
Abcam
, #
ab32389
,
1:2000
), anti-Bcl-2 (
Abcam
, #
ab185002
,
1:1000
), anti-Bax (
Abcam
,
(11)
The CTCF/LncRNA‐PACERR complex recruits E1A binding protein p300 to induce pro‐tumour macrophages in pancreatic ductal adenocarcinoma via directly regulating PTGS2 expression
Clinical and Translational Medicine
February 20, 2022
Yihao Liu et al.
were used to prepare the gel for
electrophoresis
. Antibodies against
CTCF
(
ab26271
,
Abcam
, USA), COX2 (
ab16895
;
Abcam
, USA), Glyceraldehyde 3‐phosphate dehydrogenase (GAPDH,
3936
;
CST
), β‐tubulin (
2128
;
CST
) and
(12)
Vaccinia Virus Arrests and Shifts the Cell Cycle
Viruses
February 19, 2022
Caroline K. Martin, Jerzy Samolej, Annabel T. Olson, Cosetta Bertoli, Matthew S. Wiebe, Robertus A. M. de Bruin, Jason Mercer
anti-phospho-histone γH2A.X Ser139 (
Cell Signaling
#
9718
), anti-
MCM2
(
Cell Signaling
#
12079
), anti-Mdm2 (
Abcam
ab16895
), anti-mouse-HRP (
Cell Signaling
#
7076
,
1:5000
), anti-
mouse
-IRDye 680RD (
LI-COR
926-68072
,
1:10,000
),
(13)
Preferential translation of p53 target genes
RNA biology
January 1, 2022
Hisaoka M, Schott J, Bortecen T, Lindner D, Krijgsveld J, Stoecklin G.
mouse
anti-phospho-Ser139-H2AX (γH2AX) (JBW301,
Millipore
,
05–636
), monoclonal mouse anti-MDM2 (
Abcam
,
ab16895
), polyclonal rabbit anti-phospho-Ser51-eIF2α (
Cell Signaling
, #
9721
), polyclonal rabbit anti-eIF2α (
Cell Signaling
(14)
MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathy
International journal of biological sciences
January 1, 2022
Li MR, Lei CT, Tang H, Yin XJ, Hao Z, Qiu Y, Xie YR, Zeng JY, Su H, Zhang C.
(
1:1000
,
ab71559
,
Abcam
), Desmin (
1:1000
,
BS1712
,
Bioworld Technology
, Louis Park, MN, USA), MDM2 (
1:1000
,
ab16895
,
Abcam
), active β-catenin (
1:1000
, #
4270
,
Cell Signaling Technology
, Danvers, MA, USA), β-actin (
1:10000
,
(15)
RUNX3 derived hsa_circ_0005752 accelerates the osteogenic differentiation of adipose-derived stem cells via the miR-496/MDM2-p53 pathway
Regenerative Therapy
December 1, 2021
Ming Wang, Yifan Huan, Xiyang Li, Jing Li, Guohua Lv
antibodies were applied to the
membrane
at 4 °C overnight. The primary antibodies were mouse anti-MDM2 (
ab16895
,
Abcam
), rabbit anti-p53 (
ab227655
,
Abcam
),
mouse
anti-Runx2 (
ab76956
,
Abcam
), rabbit anti-
Osx
(
ab227820
,
(16)
A role for AKT1 in nonsense-mediated mRNA decay
Nucleic Acids Research
November 8, 2021
Martine Palma, Catherine Leroy, Sophie Salomé-Desnoulez, Elisabeth Werkmeister, Rebekah Kong, Marc Mongy, Hervé Le Hir, Fabrice Lejeune
anti-Phospho AKT antibody at
1:2000
(
Cell Signaling
#
4060
), rabbit anti-MDM2 antibody at
1:1000
(
Abcam
ab16895
), rabbit anti-CBP80 antibody (H-300) at
1:1000
(
Santa Cruz Biotechnology
sc-48803
), rabbit
anti-phospho Ser/Thr ATM/ATR Substrate
(17)
Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3
Journal of experimental & clinical cancer research : CR
October 6, 2021
Jing Y, Jiang X, Lei L, Peng M, Ren J, Xiao Q, Tao Y, Tao Y, Huang J, Wang L,
et al
.
1:1000
;
Abcam
),
anti-Cyclin
D1 (
ab185241
,
1:1000
;
Abcam
), anti-
Ago2
(
ab186733
,
1:1000
;
Abcam
), anti-MDM2 (
ab16895
,
1:1000
;
Abcam
); anti-LC3 (A5179,
1:1000
), anti-p62 (A5180,
1:1000
), anti-CDK4 (A5189,
1:1000
), anti-Bax
(18)
PTEN downregulation induces apoptosis and cell cycle arrest in uterine cervical cancer cells
Experimental and Therapeutic Medicine
August 2, 2021
Jin Woo Shin, Se-Hee Kim, Jin Young Yoon
Inc.),
Bax
(
1:1,000
; cat. no.
5023
;
Cell Signaling Technologies
, Inc.), and MDM2 (
1:1,000
; cat. no.
ab16895
;
Abcam
).
Goat anti-mouse IgG-HRP
(
1:5,000
; cat. no.
sc-2005
) and
mouse anti-rabbit IgG-HRP
(
1:5,000
;
(19)
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP
Proceedings of the National Academy of Sciences of the United States of America
July 20, 2021
Chen Y, Hao Q, Wang S, Cao M, Huang Y, Weng X, Wang J, Zhang Z, He X, Lu H,
et al
.
#
2947
,
Cell Signaling Technology
), anti-Lamin B (Catalog
66095–1-Ig
,
Proteintech
), anti-MDM2 (Catalog
ab16895
,
Abcam
), anti-GAPDH (Catalog 60004–1, Proteintech), and the secondary antibodies for rabbit (Catalog
(20)
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function
Nature communications
June 25, 2021
Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, Maity D, Ali L, Kalmouni M, Hunashal Y,
et al
.
(EPR3993,
ab109199
;
Abcam
),
Noxa
(114C307,
sc-56169
;
Santa Cruz
), Bax (E63,
ab32503
;
Abcam
) or MDM2 (2A10,
ab16895
;
Abcam
) antibodies (
1:1000
), or β-actin antibody (2A3,
sc-517582
;
Santa Cruz
) (
1:2000
), overnight at
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Anti-MDM2 antibody [2A10] from Abcam
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
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