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Antibodies
Antibodies
Anti-CYR61/CCN1 antibody
Anti-CYR61/CCN1 antibody from Abcam
Be the first to write a review!
Citations:
(31)
Supplier Page
Supplier Page from
Abcam for
Anti-CYR61/CCN1 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-CYR61/CCN1 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab24448
Antibody Type
Primary
Quantity
50 UG
Isotype
IgG
Clonality
Polyclonal
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Host
Rabbit
Conjugate/Tag
Unconjugated
Concentration
0.5 mg/ml
Gene Name
CYR61
Reactivity
Human, Mouse
Target
CYR61/CCN1
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (31)
(1)
AMPK-Dependent YAP Inhibition Mediates the Protective Effect of Metformin against Obesity-Associated Endothelial Dysfunction and Inflammation
Antioxidants (Basel)
August 28, 2023
Lijing Kang, Juanjuan Yi, Chi-Wai Lau, Lei He, Qinghua Chen, Suowen Xu, Jun Li, Yin Xia, Yuanting Zhang, Yu Huang,
et al.
Transduction Laboratory, San Diego, CA, USA), rabbit anti-CTGF (
1:1000
;
ab6992
), rabbit anti-CYR61 (
1:1000
;
ab24448
), and rabbit anti-VCAM1 (
1:1000
,
ab134047
, all from
Abcam
, Cambridge, UK). After overnight
incubation
,
(2)
Cyr61 promotes Schwann cell proliferation and migration via αvβ3 integrin
BMC Molecular and Cell Biology
December 1, 2021
Zhenghui Cheng, Yawen Zhang, Yinchao Tian, Yuhan Chen, Fei Ding, Han Wu, Yuhua Ji, Mi Shen
overnight at 4 °C. The rabbit polyclonal antibody to Cyr61 (
1:500
, Abcam, Cambridge, MA, USA; Cat#
ab24448
, RRID: AB_2088724) and rabbit monoclonal antibody to c-Jun (
1:2000
,
Abcam
, Cambridge, MA, USA;
Abcam
(3)
Photosensitizer verteporfin inhibits the growth of YAP‑ and TAZ‑dominant gastric cancer cells by suppressing the anti‑apoptotic protein Survivin in a light‑independent manner
Oncology Letters
August 3, 2021
Hasegawa Hasegawa, Sugihara Sugihara, Hoshino Yoshiki, Tarumoto Tarumoto, Matsuki Matsuki, Tsutomu Tsutomu, Tomoaki Tomoaki, Nagahara Takakazu, Tomomitsu Tomomitsu, Isomoto Isomoto
anti-CTGF antibody (cat. no. L-20; Santa Cruz Biotechnology, Inc.), and
anti-CYR61/CCN1
antibody (cat. no.
ab24448
;
Abcam
). The following primary monoclonal antibodies were used for
immunofluorescence
: Anti-YAP antibody
(4)
NR4A1
knockdown confers hepatoprotection against ischaemia‐reperfusion injury by suppressing TGFβ1
via
inhibition of CYR61/NF‐κB in mouse hepatocytes
Journal of Cellular and Molecular Medicine
June 1, 2021
Jun Cao, Ting Xu, Chengming Zhou, Shaochuang Wang, Baofei Jiang, Kun Wu, Long Ma
co‐cultured with diluted antibodies to NR4A1 (
ab232375
;
1:1000
,
Abcam
, Cambridge, UK), CYR61 (1 µg/mL,
ab24448
;
Abcam
), NFκB p65 (
ab19870
; 1 µg/mL,
Abcam
), NF‐kB p65 (phospho S536) (sc‐52893; 1 µg/mL; Abcam), TGFβ1
(5)
Simvastatin Inhibits CYR61 Expression in Orbital Fibroblasts in Graves’ Ophthalmopathy through the Regulation of FoxO3a Signaling
Mediators of Inflammation
January 21, 2021
Yi-Hsuan Wei, Shu-Lang Liao, Chia-Chun Wang, Sen-Hsu Wang, Wan-Chun Tang, Chang-Hao Yang
endogenous peroxidase activity in 3% H2O2, sections were incubated overnight with anti-
CYR61
antibodies (
ab24448
,
Abcam
, Cambridge, MA, USA). The sections were washed with phosphate-buffered saline (PBS) and incubated
(6)
Circ-GLI1 promotes metastasis in melanoma through interacting with p70S6K2 to activate Hedgehog/GLI1 and Wnt/β-catenin pathways and upregulate Cyr61
Cell Death & Disease
July 1, 2020
Jun Chen, Xiaobo Zhou, Jie Yang, Qilin Sun, Yang Liu, Ningli Li, Zhen Zhang, Hui Xu
(
ab215986
), p70S6K2 (
ab184551
), GSK3β (
ab93926
), p-GSK3β (Y216) (
ab75745
), p-GSK3β (S9) (
ab75814
), Cyr61 (
ab24448
), and GAPDH (
ab8245
), were all from
Abcam
(Cambridge, MA, USA). All samples were assayed in triplicate. Fluorescent
(7)
YAP1/TAZ drives ependymoma-like tumour formation in mice
Nature communications
May 13, 2020
Eder N, Roncaroli F, Domart MC, Horswell S, Andreiuolo F, Flynn HR, Lopes AT, Claxton S, Kilday JP, Collinson L,
et al
.
at 4 °C. The following antibodies were used; CTGF (
1:1000
,
Abcam
, #
ab6992
); CYR61 (
1:1000
,
Abcam
, #
ab24448
); GAPDH (
1:5000
,
Abcam
, #
ab8245
);
GFAP
(
1:1000
, Sigma-Aldrich, #
G6171
);
HOPX
(
1:1000
, ProteinTech, #
11419-1-AP
);
(8)
Downregulation of microRNA-224-3p Hampers Retinoblastoma Progression via Activation of the Hippo-YAP Signaling Pathway by Increasing LATS2
Investigative Opthalmology & Visual Science
March 19, 2020
Lili Song, Yanxia Huang, Xinli Zhang, Shaoping Han, Min Hou, Hongxia Li
tissue growth factor (CTGF) (
1:1000
,
ab6992
), and cysteine rich angiogenic inducer 61 (CYR61) (1 µg/mL,
ab24448
), were purchased from
Abcam
, Inc. (Cambridge, UK) except p-TAZ (
1:1000
,
sc-17610-R
;
Santa Cruz
, USA).
(9)
Cyclocarya paliurus
Polysaccharide Inhibits Glioma Cell U251 Proliferation, Migration, and Invasion and Promotes Apoptosis via the GSK3
β
/
β
-Catenin Signaling Pathway
International Journal of Polymer Science
March 17, 2020
Xiaolong Du, Kai Guo, Yongqian Ma, Jianyong Chang
(
ab93926
,
Abcam
, USA), p-β-catenin (Ser33/37,
Ab11350
,
Abcam
, UK), β-catenin (
ab16051
,
Abcam
, USA), Cyr61 (
ab24448
,
Abcam
, USA), CCDN1 (
ab134175
,
Abcam
, USA), Vimentin (
ab8978
,
Abcam
, USA),
Slug
(
ab51772
,
Abcam
, USA),
(10)
Molecular signatures for CCN1, p21 and p27 in progressive mantle cell lymphoma
Journal of Cell Communication and Signaling
September 1, 2019
Afak Rasheed Salman Zaidi, Sadie Dresman, Charlotte Burt, Simon Rule, Lynn McCallum
(
1:1000
, New England Biolabs),
mouse
cyclin D1 (
1:1000
, Cell Signalling Technology), rabbit antiCCN1 (
ab24448
, Lot # GR26258–7) (
1:2000
,
Abcam
), antiGAPDH (
ab9485
) (
1:2500
,
Abcam
), mouse anti-COX IV (
ab33985
) (
1:1000
,
(11)
CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity
eLife
August 20, 2019
Park MH, Kim AK, Manandhar S, Oh SY, Jang GH, Kang L, Lee DW, Hyeon DY, Lee SH, Lee HE,
et al
.
polyclonal),
Santa Cruz
,
sc12929
RRID:AB_2252313,WB(
1:1000
)
Antibody
,
anti-CCN1
(Rabbit polyclonal),
Abcam
,
Ab24448
RRID:AB_2088724,WB(
1:1000
)
IHC
(
1:200
) Antibody,
anti-CCN1
(Rabbit polyclonal),
Novus Biologicals
,
NB100-356
(12)
Transplantation of human endometrial perivascular cells with elevated CYR61 expression induces angiogenesis and promotes repair of a full-thickness uterine injury in rat
Stem cell research & therapy
June 18, 2019
Li Z, Yan G, Diao Q, Yu F, Li X, Sheng X, Liu Y, Dai Y, Zhou H, Zhen X,
et al
.
C600220-005, Sangon Biotech, ShangHai, China) was used at a concentration of 40 ng/ml. Anti-
CYR61
antibody (
ab24448
,
Abcam
) was added in order to block
CYR61
. These cells were then incubated for 2 h at 37 °C, and tube-like
(13)
Foxc2 is essential for podocyte function
Physiological reports
May 1, 2019
Nilsson D, Heglind M, Arani Z, Enerbäck S.
beta‐1,Itgb1,
Rat
,
MAB1997
,
Millipore
,
1:200
;
1:1000
Integrin linked kinase,Ilk,Rabbit,
ab52480
,
Abcam
,
1:200
CCN1,Cyr61,Rabbit,
ab24448
,
Abcam
,
1:100
Collagen IV subunit a3,Col4a3,
Rat
,
7076
,
Chondrex
,
1:100
Collagen IV subunit a4,Col4a4,
Rat
,
7073
,
Chondrex
,
1:100
Neuropilin
(14)
Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA 4-Dependent CCN 1 Secretion
Journal of the American Heart Association
September 18, 2018
Cui S, Xue L, Yang F, Dai S, Han Z, Liu K, Liu B, Yuan Q, Cui Z, Zhang Y,
et al
.
(15)
SMYD3-associated pathway is involved in the anti-tumor effects of sulforaphane on gastric carcinoma cells
Food science and biotechnology
August 1, 2018
Dong QQ, Wang QT, Wang L, Jiang YX, Liu ML, Hu HJ, Liu Y, Zhou H, He HP, Zhang TC,
et al
.
NO.
ab187149
;
Abcam
, USA), CYR61 (rabbit antihuman Polyclonal antibody; dilution,
1:1000
; catalog NO.
ab24448
; Bioss, Beijing, China), MYL9 (rabbit anti-
human
Polyclonal antibody; dilution,
1:2000
; catalog NO. ab191393;
(16)
Targeting cysteine-rich angiogenic inducer-61 by antibody immunotherapy suppresses growth and migration of non-small cell lung cancer
Experimental and therapeutic medicine
August 1, 2018
Li X, Yuan N, Lin L, Yin L, Qu Y.
sections were incubated with
pERK
(cat. no.
ab192591
), pAKT (cat. no.
ab38449
) and CYR-61 (cat. no.
ab24448
; all
1:600
;
Abcam
) primary antibodies at 37°C for 2 h. Following washing three times with TBST, HRP-conjugated
(17)
Transcriptional Co-activator Functions of YAP and TAZ Are Inversely Regulated by Tyrosine Phosphorylation Status of Parafibromin
iScience
February 15, 2018
Chao Tang, Atsushi Takahashi-Kanemitsu, Ippei Kikuchi, Chi Ben, Masanori Hatakeyama
(18)
TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells
Cancer cell
May 8, 2017
Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V,
et al
.
antibody Polyclonal antibody,
Abcam
,Cat#
ab6992
RRID:AB_305688 Anti-CCN1 (CYR61) antibody,
Abcam
,Cat#
ab24448
RRID:AB_2088724 ,, Biological Samples,Biological Samples,Biological Samples ,, CRC TMA,Prof. Graeme
(19)
Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway
International journal of oncology
May 1, 2017
Zhang D, Wang S, Chen J, Liu H, Lu J, Jiang H, Huang A, Chen Y.
phosphatase (ALP), and cysteine-rich angiogenic inducer 61 (CYR61) antibodies (
ab125073
,
ab108337
,
ab24448
;
Abcam
) at working dilutions of
1:200
overnight at 4°C. The sections and coverslips were then incubated
(20)
Cysteine-rich 61 RNA interference inhibits pathological angiogenesis via the phosphatidylinositol 3-kinase/Akt-vascular endothelial growth factor signaling pathway in endothelial cells
Molecular Medicine Reports
November 1, 2016
Yu Di, Yiou Zhang, Linping Hui, Hongwei Yang, Yang Yang, Aiyuan Wang, Xiaolong Chen
primary antibodies overnight at 4˚C: Rabbit anti‑CCN1 polyclonal antibody (
1:2,000
dilution; cat. no.
ab24448
;
Abcam
, Cambridge, UK); rabbit anti‑phosphorylated (p)AKT1/2/3 (Ser473) polyclonal antibody (
1:2,000
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Anti-CYR61/CCN1 antibody from Abcam
Supplier Page
View Company Product Page
Pricing Info
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Company Info
Citations
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