Anti-MCM5 antibody ab17967 from Abcam

Product Specs
ItemAnti-MCM5 antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab17967
Antibody TypePrimary
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Quantity100 UG
IsotypeIgG
ClonalityPolyclonal
HostRabbit
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene NameMCM5
ReactivityHuman
TargetMCM5

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) RNAPII-dependent ATM signaling at collisions with replication forksNature communicationsAugust 24, 2023Einig E, Jin C, Andrioletti V, Macek B, Popov N.IHC, IF, FC, ChIP, ELISA" MCM2 (D7G11),3619S,Cell Signaling,H M R Mk,"WB, IP, IHC, IF, ChIP" MCM5,ab17967,Abcam,H,"WB, IHC-P" MRE11,NB100-142,Novus Biologicals,"Hu, Mu, Rt, Ch, Ha, Bt, Bv, Ca, Pm, Eq, Fe,

(2) Risk model based on minichromosome maintenance 2 using objective assessment for predicting survival of neuroblastomaiScienceFebruary 17, 2023Liang Zeng, Xiao-Yun Liu, Lei Miao, Kai Chen, Hui Xu, Liang-Jun Qin, Meng Li, Kai Liu, Jiahao Feng, Hai-Yun Wangdetection.31 The primary antibodies used were anti-MCM2 (ab4461, 1:1600; Abcam, Cambridge, UK), anti-MCM5 (ab17967, 1:1000; Abcam, Cambridge, UK), and anti-MCM6 antibodies (ab190948, 1:800; Abcam, Cambridge, UK). Computational

(3) Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomesNature communicationsOctober 14, 2022Polasek-Sedlackova H, Miller TCR, Krejci J, Rask MB, Lukas J.IF dilution: 1:1,000, 17 citations, antigen location: 1-300 aa). MCM5 #1 (rabbit, polyclonal, Abcam, ab17967, IF dilution: 1:1,000, 24 citations, antigen location: 1-55 aa) antibody was used to detect MCM5 subunit.

(4) Refining the domain architecture model of the replication origin firing factor Treslin/TICRRLife Science AllianceMay 1, 2022Pedro Ferreira, Luis Sanchez-Pulido, Anika Marko, Chris P Ponting, Dominik Boos(mouse, JL-8, 632381; Clonetech), anti-Mcm2 (goat, sc-9839; Santa Cruz Biotechnology), anti-Mcm5 (rabbit, ab17967; Abcam), anti-Cdc45 (rat, 3G10; kind gift from Helmut Pospiech), anti-PCNA (mouse, sc-56; Santa Cruz Biotechnology

(5) A Combined Treatment with Berberine and Andrographis Exhibits Enhanced Anti-Cancer Activity through Suppression of DNA Replication in Colorectal CancerPharmaceuticals (Basel)February 22, 2022Yinghui Zhao, Souvick Roy, Chuanxin Wang, Ajay GoelCell Signaling Technology, Danvers, MA, USA), anti-MCM4 (#ab124836, Abcam, Cambridge, UK), anti-MCM5 (#ab17967, Abcam, Cambridge, UK), and anti-MCM7 (#ab52489, Abcam, Cambridge, UK). After washing with 1% Tween-20

(6) The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cellsCommunications biologyJune 22, 2021Corvaisier M, Zhou J, Malycheva D, Cornella N, Chioureas D, Gustafsson NMS, Rosselló CA, Ayora S, Li T, Ekström-Holka K, et al.polyclonal antibodies: a mixture (1:1) of anti-γ-tubulin T3320 and anti-γ-tubulin T5192, anti-Mcm5 ab17967 (Abcam), and anti-FoxM1 GTX102170 (Gene Tex). PeakSeq (Version 1.31) was used for peak calling of the

(7) DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domainNature communicationsAugust 7, 2020Zhang J, Bellani MA, James RC, Pokharel D, Zhang Y, Reynolds JJ, McNee GS, Jackson AP, Stewart GS, Seidman MM.rabbit anti-MCM2, Abcam, Cat # ab4461, 1 in 200 for PLA, 1 in 1000; rabbit anti-MCM5, Abcam, Cat # ab17967, 1 in 200 for PLA, 1 in 1000; rabbit anti-MCM8, Proteintech, Cat # 16451-1-AP, 1 in 1000; rabbit anti-MCM10,

(8) 5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to ReplicationScientific ReportsDecember 1, 2019Terezia Prikrylova et al.1:1000; Abcam, cat. nr. ab4459), rabbit α -MCM5 antiserum (IF – 1:500; WB – 1:1000; Abcam, cat. nr. ab17967), Rabbit α -MCM6 antiserum (IF – 1:500; WB – 1:1000; Abcam, cat. nr. ab190948), rabbit α -MCM7 antiserum

(9) Stabilization of chromatin topology safeguards genome integrityNatureOctober 1, 2019Ochs F, Karemore G, Miron E, Brown J, Sedlackova H, Rask MB, Lampe M, Buckle V, Schermelleh L, Lukas J, et al.NUDC 420 KAP1 (rabbit, Bethyl Laboratories, A300-274A, 1:2000 for WB), MCM2 (mouse, 422 Abcam, ab17967, 1:200 for IF), MCM7 (mouse, Santa Cruz, sc-9966, 1:1000 for 424 (rabbit, Sigma-Aldrich, HPA027183,

(10) Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.OncogeneJune 1, 2019Amy E. Schade, Matthew G. Oser, Hilary E. Nicholson, James A. DeCaprioSanta Cruz), anti-E2F4 (C-20, Santa Cruz), IgG (2729, Cell Signaling), anti-LIN9 (BL2981, Bethyl), anti-MCM5 (ab17967, Abcam), anti-p107 (C-18, Santa Cruz), anti-p130 (C-20, Santa Cruz), anti-p130-pS672 (ab76255, Abcam),

(11) The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7PLOS BiologyJanuary 29, 2019Kerstin Köhler, Luis Sanchez-Pulido, Verena Höfer, Anika Marko, Chris P. Ponting, Ambrosius P. Snijders, Regina Feederle, Aloys Schepers, Dominik Boos3G10 human Cdc45 rat Kind gift of H. Pospiech und F. Grosse anti-Mcm5 human Mcm5 rabbit Abcam, ab17967 anti-Sld5 human Sld5 rabbit Abcam, ab139683 Abbreviations: BD, Becton Dickinson; BrdU, 5-bromodeoxyuridine;

(12) Expression variation and covariation impair analog and enable binary signaling controlMolecular Systems BiologyMay 16, 2018Kyle M Kovary, Brooks Taylor, Michael L Zhao, Mary N Teruel[E460] to ERK2,Abcam,ab32081 MEK1/2 (L38C12) Mouse mAb,Cell Signaling,4694S Rabbit anti‐MCM5,Abcam,ab17967 Mouse anti‐MCM7,Abcam,ab2360 Rabbit anti‐ENO1 (Enolase),Abcam,ab155102 Anti‐GAPDH antibody [6C5]

(13) Ensa controls S-phase length by modulating Treslin levelsNature CommunicationsDecember 1, 2017Sophie Charrasse, Aicha Gharbi-Ayachi, Andrew Burgess, Jorge Vera, Khaled Hached, Peggy Raynaud, Etienne Schwob, Thierry Lorca, Anna CastroAbcam, ab4461), MCM-3 (1/2500, Abcam, ab4460), MCM-4 (1/5000, Abcam, ab4459) and MCM-5 (1/5000, Abcam, ab17967). Mouse monoclonal used are MCM-7 antibody (1/1000, Abcam, ab2360), Flag M2 (1/500, Sigma, F3165), Vinculin

(14) H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firingNucleic acids researchMarch 11, 2015Rondinelli B, Schwerer H, Antonini E, Gaviraghi M, Lupi A, Frenquelli M, Cittaro D, Segalla S, Lemaitre JM, Tonon G.(Cell Signaling, Cat. # 9125, 1:1000); α-LAMIN B (Sc-6216, Clone C20, 1:500); α-MCM5 (Abcam, Cat. # ab17967, 1:2000); α-MCM2 (Abcam, Cat. # ab4461, 1:1000); α-CDC45 (Santa Cruz, Cat. # C20, 1:500); α-PCNA (Santa Cruz

(15) Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiationThe Journal of biological chemistryDecember 26, 2014Yanzhe Gao, Jianhong Yao, Sumeet Poudel, Eric Romer, Lubna Abu-Niaaj, Michael Leffak

(16) Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like stateCell Death & DiseaseJuly 24, 2014A Maya-Mendoza, J M Merchut-Maya, J Bartkova, J Bartek, C H Streuli, D A Jackson9661S); Cyclin E (Abcam ab3927, Cambridge, UK); PCNA (Abcam ab18197); MCM4 (Abcam ab4459); MCM5 (Abcam ab17967); Orc1 (Abcam ab 85830); Cdt1 (Abcam ab70829); Geminin (Abcam ab12147); β-Actin (Sigma A1978); pRb Ser

(17) A role for DNA polymerase θ in the timing of DNA replicationNature communicationsJuly 3, 2014Fernandez-Vidal A, Guitton-Sert L, Cadoret JC, Drac M, Schwob E, Baldacci G, Cazaux C, Hoffmann JS.Danvers, USA), Mcm2 (ab4461, 1:2,000, Abcam), Mcm4-G7 (sc-28317, 1:2,000, Santa Cruz Biotechnology), Mcm5 (ab17967, 1:5,000, Abcam), Mcm7 (sc-22782, 1:1,000, Santa Cruz Biotechnology), Orc2 (M055-3, 1:1,000, MBL, Woburn,

(18) The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinksMolecular cellNovember 7, 2013Jing Huang, Shuo Liu, Marina A Bellani, Arun Kalliat Thazhathveetil, Chen Ling, Johan P de Winter, Yinsheng Wang, Weidong Wang, Michael M Seidman

(19) A reduction of licensed origins reveals strain-specific replication dynamics in miceMammalian GenomeOctober 1, 2011Tsuyoshi Kawabata, Satoru Yamaguchi, Tavanna Buske, Spencer W. Luebben, Marsha Wallace, Ilze Matise, John C. Schimenti, Naoko Shimareplated for experimental use. Antibodies We used Abcam anti-MCM antibodies (ab3159, ab4460, ab4459, ab17967, ab4458 and ab2360 for MCM2, MCM3, MCM4, MCM5, MCM6 and MCM7, respectively), anti-CDC45 (Abcam; ab56476),

(20) MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survivalCell Death & DifferentiationJune 1, 2011E A Afanasyeva et al.

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Anti-MCM5 antibody from Abcam

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Anti-MCM5 antibody from Abcam

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