Alexa Fluor(R) 488 anti-mouse/human Helios 137223 from BioLegend

Product Specs
ItemAlexa Fluor(R) 488 anti-mouse/human Helios
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number137223
HostArmenian Hamster
NCBI Gene AliasesHELIOS, Helios, ZNF1A2, A730095J18Rik, ANF1A2, Znfn1a2, Zfpn1a2, ZNFN1A2
ApplicationsIntracellular Staining for Flow Cytometry (ICFC)
Conjugate/TagAlexa Fluor® 488
ReactivityMouse, Human
IsotypeIgG
Quantity100 tests
Clone22F6
Antibody TypePrimary
NCBI Full Gene NameIKAROS family zinc finger 2
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ImmunogenHelios peptide (aa 51-107)
ClonalityMonoclonal
TargetHelios

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San Diego, California 92121

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Fax: 1-877-455-9587

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Website: biolegend.com

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(3) Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal InterfaceCell reportsMay 28, 2019Salvany-Celades M, van der Zwan A, Benner M, Setrajcic-Dragos V, Bougleux Gomes HA, Iyer V, Norwitz ER, Strominger JL, Tilburgs T.

(4) Ets1 suppresses atopic dermatitis by suppressing pathogenic T cell responsesJCI insightMarch 7, 2019Lee CG, Kwon HK, Kang H, Kim Y, Nam JH, Won YH, Park S, Kim T, Kang K, Rudra D, et al.

(5) Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cellsScience (New York, N.Y.)May 25, 2018Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, et al.

(6) Alloantigen-specific regulatory T cells generated with a chimeric antigen receptorThe Journal of clinical investigationApril 1, 2016MacDonald KG, Hoeppli RE, Huang Q, Gillies J, Luciani DS, Orban PC, Broady R, Levings MK.British Columbia). Intracellular staining was performed for FOXP3 (12-4777-42, eBioscience), Helios (137223, Biolegend), CTLA-4 (555855 and 562743, BD Biosciences), IL-2 (559334, BD Biosciences), IFN-γ (557844,

(7) Natural and inducible Tregs in swine: Helios expression and functional propertiesDevelopmental and comparative immunologyApril 1, 2015Käser T, Mair KH, Hammer SE, Gerner W, Saalmüller A.

(8) Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3⁺ Treg cellsJournal of immunological methodsDecember 1, 2014Verhagen J, Wraith DC.

(9) Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and miceImmunology and cell biologySeptember 1, 2014Bedke T, Iannitti RG, De Luca A, Giovannini G, Fallarino F, Berges C, Latgé JP, Einsele H, Romani L, Topp MS.

(10) Lactobacillus reuteri DSM 17938 differentially modulates effector memory T cells and Foxp3+ regulatory T cells in a mouse model of necrotizing enterocolitisAmerican journal of physiology. Gastrointestinal and liver physiologyJuly 15, 2014Liu Y, Tran DQ, Fatheree NY, Marc Rhoads J.

(11) Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacityPloS oneJanuary 1, 2014Angin M, Klarenbeek PL, King M, Sharma SM, Moodley ES, Rezai A, Piechocka-Trocha A, Toth I, Chan AT, Goulder PJ, et al.

(12) Identification of novel HLA class II target epitopes for generation of donor-specific T regulatory cellsClinical immunology (Orlando, Fla.)November 1, 2012Stone B, Rieck M, Rawlings CA, Kas A, Shendure J, Jones H, Buckner JH.

(13) Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cellsProceedings of the National Academy of Sciences of the United States of AmericaOctober 2, 2012Vaeth M, Schliesser U, Müller G, Reissig S, Satoh K, Tuettenberg A, Jonuleit H, Waisman A, Müller MR, Serfling E, et al.

(14) Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumorsNeuro-oncologyDecember 1, 2011Wainwright DA, Sengupta S, Han Y, Lesniak MS.

(15) Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cellsJournal of immunology (Baltimore, Md. : 1950)April 1, 2010Thornton AM, Korty PE, Tran DQ, Wohlfert EA, Murray PE, Belkaid Y, Shevach EM.

(16) Effects of presynaptic polypeptide neurotoxins from tiger snake venom (notechis-II-5 and notexin) on frog neuromuscular junctionPhysiologia BohemoslovacaJanuary 1, 1978L G Magazanik, T I Slavnova

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(1)

1/19/2018Good Helios Antibody Mahesh RaundhalThe goal of this experiment was to assess the expression of Helios in lung CD4+ T cells. This product was selected because of the AF488 tag as it has no spillover into other channels.

Alexa Fluor(R) 488 anti-mouse/human Helios from BioLegend

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Alexa Fluor(R) 488 anti-mouse/human Helios from BioLegend

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