InVivoMAb anti-mouse IL-27 p28 BE0326-R001mg from Bio X Cell

Description

Bio X Cell InVivoMAb anti-mouse IL-27 p28 Monoclonal Antibody has the following reported applications: in vivo IL-27 p28 neutralization, in vitro IL-27 p28 neutralization, Flow cytometry. It features greater than 95% purity, ultra-low endotoxin levels, and are preservative, stabilizer, and carrier protein-free

Product Specs
ItemInVivoMAb anti-mouse IL-27 p28
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0326-R001mg
Quantity1 mg
Applicationsin vivo IL-27 p28 neutralization, in vitro IL-27 p28 neutralization, Flow cytometry
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
Reactivitymouse
TargetIL-27 p28
IsotypeIgG2a, κ
CloneMM27.7B1
HostMouse
Antibody TypePrimary Antibody
ImmunogenMouse IL-27
NCBI Full Gene Nameinterleukin 27
NCBI Gene AliasesIL-27, IL-27-A, IL-27p28, IL27-A, Il30, p28
ClonalityMonoclonal
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaCancer Biology, Cytokine and Chemokine, Immunology, Innate Immunity, Tumor Antigens

Specifications/Features

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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Bio X Cell

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

Company Profile

Website: bioxcell.com

(1) Interleukin-27 promotes CD8+ T cell reconstitution following antibody-mediated lymphoablationJCI insightApril 4, 2019Ayasoufi K, Zwick DB, Fan R, Hasgur S, Nicosia M, Gorbacheva V, Keslar KS, Min B, Fairchild RL, Valujskikh A.

(2) Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infectionNature communicationsNovember 28, 2018Xin G, Zander R, Schauder DM, Chen Y, Weinstein JS, Drobyski WR, Tarakanova V, Craft J, Cui W.

(3) Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus PersistencePLoS pathogensDecember 1, 2016Clement M, Marsden M, Stacey MA, Abdul-Karim J, Gimeno Brias S, Costa Bento D, Scurr MJ, Ghazal P, Weaver CT, Carlesso G, et al.

(4) A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiationJournal of autoimmunityMay 1, 2015Anderson AC, Sullivan JM, Tan DJ, Lee DH, Kuchroo VK.

(5) Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27Journal of leukocyte biologyJuly 1, 2014Bosmann M, Strobl B, Kichler N, Rigler D, Grailer JJ, Pache F, Murray PJ, Müller M, Ward PA.

(6) IL-27p28 is essential for parent-to-F1 acute graft-versus-host diseaseEuropean journal of immunologyJuly 1, 2014Marillier RG, Uyttenhove C, Goriely S, Marbaix E, Van Snick J.

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