Fig 1: AP000439.2-deleted exosome suppressed tumor growth. Xenograft tumor was established by injecting Caki-1 cells, in the meantime, mice treated with AP000439.2-deleted exosome or NC exosome via tail vein injection. A Xenograft tumor images from each mouse. B Body weight curve of mice. C Tumor weight of mice from two groups. D Tumor volume curve of mice from two groups. E The proportion of M1 (F4/80+NOS2+) and M2 (F4/80+CD163+) macrophages in tumor tissues by flow cytometry. *p < 0.05, **p < 0.01. Two-tailed Student’s t-test