CD4 (D7D2Z) Rabbit mAb 25229T from Cell Signaling Technology

Product Specs
ItemCD4 (D7D2Z) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number25229T
Quantity20 µl
ApplicationsW, IHC-Bond, IHC-P
ReactivityM, R
TargetCD4 mouse
HostRabbit
NCBI Full Gene NameCD4 antigen
NCBI Gene AliasesL3T4, Ly-4
ClonalityMonoclonal
Research AreaImmunology and Inflammation
Molecular Weight55

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) APOBEC-1 deletion enhances cisplatin-induced acute kidney injurySci RepDecember 14, 2023Xiaojia Guo, Valerie Blanc, Nicholas O. Davidson, Heino Velazquez, Tian-Min Chen, Dennis G. Moledina, Gilbert W. Moeckel, Robert L. Safirstein, Gary V. Desiranti-Ly6b (Catlogue # MCA771G, BioRad, Hercules, CA, USA); anti-CD4, anti-CD8, and F4/80 (Catalogue # 25229, 98941, and 70076, respectively, Cell Signaling Technologies, Danvers, MA, USA). Signals of all primary

(2) [18F]FDG PET-MR characterization of aortitis in the IL1rn−/− mouse model of giant-cell arteritisEJNMMI ResearchNovember 29, 2023Samuel Deshayes, Caroline Baugé, Pierre-Antoine Dupont, Christophe Simard, Hanan Rida, Hubert de Boysson, Alain Manrique, Achille Aoubaand according to the manufacturer’s protocols: anti-CD4 (1:50, Cell Signalling, catalogue number: #25229), anti-CD8α (1:200, Cell Signalling, catalogue number: #98941), anti-CD31 (1:100, Cell Signalling, catalogue

(3) CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockadeNature CommunicationsNovember 18, 2023Tomoko Yamamori Morita, Jie Yu, Yukie Kashima, Ryo Kamata, Gaku Yamamoto, Tatsunori Minamide, Chiaki Mashima, Miyuki Yoshiya, Yuta Sakae, Toyohiro Yamauchi, et al.Hokkaido, Japan) using primary antibodies against anti-CD3 (SP7) (GeneTex, #GTX16669), anti-CD4 (D7D2Z) (#25229, Cell Signaling Technology), anti-CD8 (D4W2Z) (#98941, Cell Signaling Technology), anti-CD11c (N418)

(4) Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinomaJournal of Experimental & Clinical Cancer ResearchNovember 16, 2023Jialiang Wang, Xiaoyu Zhang, Xinyi Ma, Dongmei Chen, Meina Cai, Lexin Xiao, Jing Li, Zexuan Huang, Yuehua Huang, Yifan LianAbcam), anti-CD206 (ab64693, Abcam), anti-CD206 (141704, Biolegend, for flow cytometry only), anti-CD4 (25229, Cell Signaling Technology), anti-CD8 (98941, Cell Signaling Technology), anti-F4/80 (123137, Biolegend),

(5) Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responsesClinical and Experimental MedicineNovember 8, 2023Simon Heller, Sarah Glaeske, Katja Gluske, Juliane Paul, Annika Böhme, Andreas Janzer, Helge Gottfried Roider, Anna Montebaur, Barbara Nicke, Ralf Lesche, et al.IgG1,k",EH12.2H7,BioLegend,329918 Anti-mouse CD3,Rabbit IgG,E4T1B,CellSignaling,78588 Anti-mouse CD4,Rabbit IgG,D7D2Z,CellSignaling,25229 Anti-mouse CD8,Rabbit IgG,D4W2Z,CellSignaling,98941 Anti-mouse FOXP3,Rabbit IgG,D6O8R,CellSignaling,12653 Anti-mouse

(6) Full eradication of pre‐clinical human papilloma virus‐induced tumors by a lentiviral vaccineEMBO Molecular MedicineOctober 11, 2023Laëtitia Douguet, Ingrid Fert, Jodie Lopez, Benjamin Vesin, Fabien Le Chevalier, Fanny Moncoq, Pierre Authié, Trang‐My Nguyen, Amandine Noirat, Fabien Névo, et al.7‐μm‐thick cryostat sections on Leica Bond RX using rabbit anti‐mouse CD4 (Cell signaling, D7D2Z, #25229) or CD8 (Cell signaling, D8A8Y, #85336) antibody and biotinylated goat anti‐rabbit Ig secondary antibody

(7) Immunization with a multi-antigen targeted DNA vaccine eliminates chemoresistant pancreatic cancer by disrupting tumor-stromal cell crosstalkJournal of Translational MedicineOctober 9, 2023Hongquan Qin, Jiali Chen, Katia Bouchekioua-Bouzaghou, Ya-Ming Meng, Jordi Bach Griera, Xue Jiang, Xiangzhan Kong, Minghui Wang, Qiuping Xu, Ping-Pui WongSanta Cruz Biotechnology-sc-20034), GFRAL (Abcam-ab107719), GDF15 (Santa Cruz Biotechnology-sc-377195), CD4 (D7D2Z, Cell signaling-#25229), CD8 (D4W2Z, Cell signaling-#98941) or Granzyme B (D6E9W,Cell signaling-# 46890S) antibody at 4 °C

(8) A novel [89Zr]-anti-PD-1-PET-CT to assess response to PD-1/PD-L1 blockade in lung cancerFrontiers in ImmunologySeptember 28, 2023Ander Puyalto, María Rodríguez-Remírez, Inés López, Fabiola Iribarren, Jon Ander Simón, Marga Ecay, María Collantes, Anna Vilalta-Lacarra, Alejandro Francisco-Cruz, Jose Luis Solórzano, et al.Cambridge, United Kingdom), CD8 (1:400, #98941S; Cell Signaling, Danvers, MA, USA) and CD4 (1:400, #25229S; Cell Signaling, Danvers, MA, USA), as previously described (16). Slides were scanned using the Aperio

(9) Neoadjuvant use of oncolytic herpes virus G47Δ prevents local recurrence after insufficient resection in tongue cancer modelsMolecular Therapy - OncolyticsSeptember 21, 2023Kosuke Inoue, Hirotaka Ito, Miwako Iwai, Minoru Tanaka, Yoshiyuki Mori, Tomoki Todoantibodies purchased from Cell Signaling Technology were used for immunohistochemistry: CD4 (1:50, 25229S), CD8 (1:200, 98941S), FoxP3 (1:800, 12653S), and F4/80 (1:200, 70076S). Antigen retrieval was performed

(10) Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrateFrontiers in ImmunologySeptember 18, 2023Ken Liu, Jinbiao Chen, Yang Zhao, Jade Boland, Ka Ka Ting, Glen Lockwood, Catriona McKenzie, James Kench, Mathew A. Vadas, Jennifer R. Gamble, et al.ab184006) were bought from Abcam (Cambridge, CB4 0FL, UK). Antibodies against CD31 (cat# 77699), CD4 (cat# 25229), CD8 (cat# 98941) and FOXP3 (cat# 12653) were obtained from Cell Signaling Technology (Danvers, MA,

(11) MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast CancerNature communicationsSeptember 13, 2023Doha ZO, Wang X, Calistri NL, Eng J, Daniel CJ, Ternes L, Kim EN, Pelz C, Munks M, Betts C, et al.#sc-692, 1:500); F4/80 (Serotec A3-1, 1:200); CD11C (Cell Signaling #97585,1:100); CD4 (Cell Signaling #25229, 1:100); MHCII (eBioscience #eB14-5321, 1:100); BTK (LSBio #LS-C180161, 1:100); CD45 (BD Bioscience

(12) Aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activityActa Pharmaceutica Sinica BSeptember 1, 2023Xin Tang, Chuanxi Wang, Lei Wang, Feifei Ren, Runqiao Kuang, Zhenhua Li, Xue Han, Yiming Chen, Guodong Chen, Xiuqing Wu, et al.APC annexin V apoptosis detection kit with 7-AAD was obtained from BioLegend (CA, USA). Anti-CD4 (catalog 25229 S, 1:100), anti-IL-17A (catalog 13838 S, 1:1000 for Western blotting), and anti-β-Actin (catalog 3700

(13) Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancementCell death discoveryAugust 28, 2023Jia H, Wei P, Zhou S, Hu Y, Zhang C, Liang L, Li B, Gan Z, Xia Y, Jiang H, et al.incubated overnight at 4 °C with primary antibodies (CD3, 1:100, OmnimAbs, OM244830; CD4, 1:200, CST, 25229S; CD8, 1:800, CST, 98941S; Granzyme B, 1:200, Bioworld, BS1152; CD86, 1:400, Novus, NBP2-25208; CD11b,

(14) Dual Blockade of EP2 and EP4 Signaling is Required for Optimal Immune Activation and Anti-Tumor Activity Against Prostaglandin-Expressing TumorsCancer Research CommunicationsAugust 8, 2023Brian J. Francica, Anja Holtz, Justine M Lopez, David Freund, Austin Chen, Dingzhi Wang, David Powell, Franciele C Kipper, Dipak Panigrahy, Raymond N. DuBois, et al.Antibody,Company,Catalog no.,Isotype,Type,Reactivity CD4,Cell Signaling Technology,25229S,IgG,Rabbit IgG mAb,"Mouse, Rat" CD8,Cell Signaling Technology,98941,IgG,Rabbit IgG mAb,Mouse FoxP3,Cell Signaling Technology

(15) The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I-Mediated Immune ResponseCancer researchJune 2, 2023Zhang L, Li Y, Zhou L, Zhou H, Ye L, Ou T, Hong H, Zheng S, Zhou Z, Wu K, et al.20566–1-AP, Proteintech, RRID: AB_10700006), EPCAM (1:200, EM1111, HuaBio, RRID: AB_2928115), CD4 (1:200, 25229, Cell Signaling Technology, RRID: AB_2798898), CD8 (1:200, A11856, ABclonal, RRID: AB_2758823), and

(16) Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular CarcinomaMolecular cancer therapeuticsJune 1, 2023Mender I, Siteni S, Barron S, Flusche AM, Kubota N, Yu C, Cornelius C, Tedone E, Maziveyi M, Grichuk A, et al.μmol/L thick) were evaluated using antibodies against CD4 (1:50; Cell Signaling Technology, Catalog No. 25229, RRID: AB_2798898), CD8α (1:200; Cell Signaling Technology, Catalog No. 98941, RRID: AB_2756376), CD11c

(17) An Fc-muted bispecific antibody targeting PD-L1 and 4-1BB induces antitumor immune activity in colorectal cancer without systemic toxicityCellular & molecular biology lettersMay 31, 2023Cheng LS, Zhu M, Gao Y, Liu WT, Yin W, Zhou P, Zhu Z, Niu L, Zeng X, Zhang D, et al.primary antibodies and fluorescent dyes included anti-CD3 antibody (78588T, CST)/TSA 700, anti-CD4 (25229T, CST)/TSA 570, anti-CD8 (98941T, CST)/TSA 520, and anti-NK1.1 (NB100-77528SS, Novus)/TSA 650. Each slide

(18) Human umbilical cord mesenchymal stem cell treatment alleviates symptoms in an atopic dermatitis-like mouse modelStem cell research & therapyMay 29, 2023Hua C, Liang Q, Chen S, Zhu J, Tang Y, Chen X, Song Y, van der Veen S, Cheng H.previously [33]. Primary antibodies used for immunohistochemistry staining were Ki67 (#12202s, CST), CD4 (#25229S, CST), CD8 (#98941S, CST), CD1a (#17325-1-AP, Proteintech), CXCR3 (#26756-1-AP, Proteintech), CCR3 (#bs-1167R,

(19) IFN‐γ–STAT1‐mediated NK2R expression is involved in the induction of antitumor effector CD8 + T cells in vivoCancer ScienceMay 1, 2023Weidong Shen, Xiangdong Wang, Huihui Xiang, Shunsuke Shichi, Hiroki Nakamoto, Saori Kimura, Ko Sugiyama, Akinobu Taketomi, Hidemitsu Kitamurapurchased from PeproTech EC. 7‐AAD Viability Dye was purchased from BECKMAN COULTER. Rabbit CD4 (D7D2Z) (#25229) and CD8α (D4W2Z) (#98941) mAbs for immunohistochemistry were obtained from Cell Signaling Technology.

(20) Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinomaCell reports. MedicineApril 18, 2023Ochoa MC, Sanchez-Gregorio S, de Andrea CE, Garasa S, Alvarez M, Olivera I, Glez-Vaz J, Luri-Rey C, Etxeberria I, Cirella A, et al.(D6O8R),Cell Signaling Technology,12653;RRID:AB_2797979 Anti-CD4 (D7D2Z),Cell Signaling Technology,25229;RRID:AB_2798898 Anti-CD11b (6H12),Nous Biologicals,NB110-89474;RRID:AB_1216361 Anti-KI-67 (rabbit

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CD4 (D7D2Z) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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CD4 (D7D2Z) Rabbit mAb from Cell Signaling Technology

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