Fig 2: Abscess in a mouse 4 days after intravenous Candida albicans injection with 4.5 × 104 yeasts/gm/mouse. Hyphae and yeast cell surfaces are decorated with mouse SAP (brown). This tissue section was chosen because no mouse tissue is seen in the abscess. Mouse tissue would show extensive SAP since it is an integral component of basement membrane.

Fig 3: Kaplan–Meier Survival plot (in hours). Mice receiving yeast cells alone (red) vs. mice receiving yeast cells and SAP SQ (green); all mice received 4.5 × 104 yeasts/gram/mouse intravenously on day 0. (n = 38 mice).

Fig 4: Kaplan–Meier Survival plot (in hours) with confidence limits of 4 treatment groups injected with C. albicans. Each group of 5 mice was injected with 4.5 × 104 yeasts/gram/mouse intravenously at day 0: mice administered yeast cells (red); mice administered yeast cells and SAP SQ (blue); mice administered yeast cells and SAP SQ and given miridesap in the drinking water (green); and mice administered yeast cells and miridesap in the drinking water but no SAP (purple); 4.5 × 104 yeasts/gm of mouse were administered intravenously at day 0.