Fig 1: The inhibition of Zfp90 modulated the cisplatin−induced active caspase−3, Bcl−2, Bax protein expression of SK−OV−3 and ES−2 cells. SK−OV−3 and ES−2 cells were treated with 20 μM cisplatin for 24 h in the si−Ctrl or si−Zfp90 cells, and protein expression was determined by western blotting. (A) active caspase-3, Bcl−2, Bax protein expression of si−Ctrl, cisplatin, si−Zfp90, and the si−Zfp90 and cisplatin group were detected in SK−OV−3 cell. Quantitative results of (B) active caspase−3, (C) Bcl−2 and (D) Bax were shown. (E) active caspase−3, Bcl−2, Bax protein expression of si−Ctrl, cisplatin, si−Zfp90, and the si−Zfp90 and cisplatin group was also observed in ES−2 cell. Quantitative results of (F) active caspase−3, (G) Bcl−2, and (H) Bax were shown. Data are expressed as the mean ± SEM (n = 3) (*, p < 0.05, versus si−Ctrl group; #, p < 0.05, versus cisplatin group).