Fig 1: (A) Some activated and inactivated protein kinase were predicted by iKAP. (B) According to the kinase-site phosphorylation network, phosphorylation levels of PKCa that was enriched in Wnt pathway at T497 were positively correlated with STLK3 and MST1. (C) Western blotting validation. Differential expression levels of STLK3, MST1, and p-PKCa in RCT and normal tissues were verified using western blotting analysis. Paired samples t-test was used. *p < 0.05, **p < 0.01.