Fig 1: TSPAN1 mediates ITGA2 hypomethylation in OC cells. (a) qRT-PCR detection and western blotting of ITGA2 expressions in OC cell model and normal cells. (b) qRT-PCR detection and western blotting of ITGA2 expressions in A2780 cells following transfection with either si-DARS-AS1, si-TSPAN1, or oe-TSPAN1. (c) ChIP detection of ITGA2 enrichments in immunoprecipitates using anti-TSPAN1, anti-TET2, and anti-DNMT3B in A2780 cells after TSPAN1 knockdown or overexpression. A symbol of * represents p < 0.05.
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