Description
Product Characteristics: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.,SNAI2,SLUG,SLUGH,SLUGH1,SNAIL2,WS2D,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Neural Stem Cell marker,SNAI2
Target Information: transcriptional repressor, involved in epithelial-mesenchymal transition [RGD, Feb 2006]