Anti-DDIT3 antibody [9C8] ab11419 from Abcam

Product Specs
ItemAnti-DDIT3 antibody [9C8]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab11419
Antibody TypePrimary
ClonalityMonoclonal
Clone9C8
HostMouse, Nude mouse
Quantity10 UG, 100 UG
ApplicationsImmunocytochemistry/ Immunofluorescence, Western blot, Immunocytochemistry/ Immunofluorescence, Western blot
IsotypeIgG2b
Conjugate/TagUnconjugated
Concentration1 mg/ml
Research AreaEpigenetics
Gene NameDDIT3
ReactivityHuman, Mouse
TargetDDIT3

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Tanshinone IIA attenuates valvular interstitial cells’ calcification induced by oxidized low density lipoprotein via reducing endoplasmic reticulum stressOpen Med (Wars)September 25, 2023Fang Chen, Dongqiang Yang, Yuhua Ru, Yu Bai, Xueliang Pei, Jie Sun, Shan Cao, Weiguang Wang, Aishe GaoSanta Cruz Biotechnology, Inc. (Santa Cruz, CA) except GRP78, CHOP, and XBP1s (Abcam; Cat. ab212054, ab11419, ab241571). Porcine VICs were dissolved in commercial radio immunoprecipitation assay lysis buffer (Beyotime,

(2) Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitorsSignal Transduction and Targeted TherapySeptember 25, 2023Bopei Cui, Lifang Song, Qian Wang, Kelei Li, Qian He, Xing Wu, Fan Gao, Mingchen Liu, Chaoqiang An, Qiushuang Gao, et al.p-JNK (1: 1000, 4668, Cell Signaling Technology), Caspase 12 (1: 2000, ab62484, Abcam), CHOP (1: 1000, ab11419, Abcam), PERK (1: 1000, 5683, Cell Signaling Technology), p-PERK (1: 1000, 3179, Cell Signaling Technology),

(3) Zinc oxide nanoparticles inhibit malignant progression and chemotherapy resistance of ovarian cancer cells by activating endoplasmic reticulum stress and promoting autophagyExperimental and Therapeutic MedicineSeptember 14, 2023Wenli Gu, Caihong Yangfactor 4 (ATF4; 1:1,000; cat. no. ab270980; Abcam), C/EBP homologous protein (CHOP; 1:1,000; cat. no. ab11419; Abcam), Caspase 12 (1:1,000; cat. no. ab62484; Abcam), LC3 (1:1,000; cat. no. ab192890; Abcam), Beclin1

(4) Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCCScience AdvancesSeptember 13, 2023Ebru Boslem, Saskia Reibe, Rodrigo Carlessi, Benoit Smeuninx, Surafel Tegegne, Casey L. Egan, Emma McLennan, Lauren V. Terry, Max Nobis, Andre Mu, et al.against p-JNK (9251, Cell Signaling Technology), total JNK (9252, Cell Signaling Technology), CHOP/ddit3 (ab11419, Abcam), calnexin (2679, Cell Signaling Technology), heat HSF1 (4356, Cell Signaling Technology), phospho-eif2α

(5) GRP78 inhibitor HA15 increases the effect of Bortezomib on eradicating multiple myeloma cells through triggering endoplasmic reticulum stressHeliyonSeptember 2, 2023Yirong Chen, Yuchen Tao, Kexin Hu, Jiahui Lu(1:1500, ab182858, Abcam), GRP78 (1:1000, ab21685, Abcam), ATF4 (1:1000, ab216839, Abcam), CHOP (1:1000, ab11419, Abcam), XBP1 (1:1500, ab37152, Abcam), and β-actin (1:300, ab8226, Abcam) for 1 h at room temperature.

(6) Esophageal cancer stem cells reduce hypoxia-induced apoptosis by inhibiting the GRP78-perk-eIF2α-ATF4-CHOP pathway in vitroJournal of Gastrointestinal OncologyAugust 31, 2023Ruijiang Lin, Minjie Ma, Biao Han, Ya Zheng, Yuping Wang, Yongning Zhourabbit anti-Caspase 12 polyclonal antibody (ab62484; Abcam); rabbit anti-CHOP monoclonal antibody (ab11419; Abcam); rabbit anti-GRP78 monoclonal antibody (ab108615; Abcam); rabbit anti-JNK monoclonal antibody

(7) Characterization of circSEC11A as a novel regulator of Iodine-125 radioactive seed-induced anticancer effects in hepatocellular carcinoma via targeting ZHX2/GADD34 axisCell Death DiscovAugust 10, 2023Dong Li, Wujie Wang, Bin Liu, Die Jin, Yang Wang, Guanghui He, Lei Guo, Wen Liu, Yuliang Liincluding ZHX2 (ab205532), GADD34 (ab9869), eIF2α (ab169528), p-eIF2α (32157), ATF4 (ab184909), and CHOP (ab11419), were purchased form Abcam (Cambridge, UK). The secondary antibodies were purchased from ABclonal (Wuhan,

(8) Houttuynia cordata Thunb. Hexane fraction induces MDA-MB-231 cell apoptosis via caspases, ER stress, cell cycle arrest and attenuated Akt/ERK signalingHeliyonJuly 28, 2023Pitsinee Inthi, Hataichanok Pandith, Prachya Kongtawelert, Subhawat Subhawa, Ratana Banjerdpongchai(ab227443), Akt (ab32505), pAkt (Ser473) (ab81283), ERK (ab196883), pERK (ab76299), GRP78 (ab21685), DDIT3 (ab11419), β-actin (ab8227) and peroxidase-labeled secondary antibodies: goat anti-rabbit IgG (ab97051) and goat

(9) Schlafen4+-MDSC in Helicobacter-induced gastric metaplasia reveals role for GTPasesFrontiers in ImmunologyJune 2, 2023Lin Ding, Sulaiman Sheriff, Ricky A. Sontz, Juanita L. Merchantprimary antibodies to SLFN4 peptides (custom made by GenScript), NOS2 (Abcam, #ab283655), CHOP (Abcam, #ab11419), cleaved Caspase-3 (Cell Signaling, #9661), β-Tubulin (Cell signaling, #5346S), GAPDH (MA5-15738, ThermoFisher). Nucleotide

(10) FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein responseRedox biologyApril 1, 2023Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X.24164-1-AP), p-JNK (1:1500; Proteintech, 80024-1-RR), XBP1 (1:1000; Abcam, ab220783), CHOP (1:1000; Abcam, ab11419), ATF6 (1:1000; Proteintech, 24169-1-AP), and POMT2 (1:1000; Invitrogen, PA5-51987). HRP-conjugated

(11) Renalase Prevents Renal Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Down-Regulating GSK-3β/Snail SignalingInternational Journal of Medical SciencesMarch 21, 2023Yiru Wu, Yu Bai, Yiduo Feng, Qidong Zhang, Zongli Diao, Wenhu Liu(Col-I) (Cat No. 14695-1-AP, Proteintech), PERK (ab229912; Abcam, USA), ATF4 (ab216839, Abcam), CHOP (ab11419, Abcam), GSK-3β (ab93926, Abcam), p-GSK-3β-Ser9 (ab131097 Abcam), and p-GSK-3β-Tyr216 (Cat No. 29125-1-AP,

(12) Sex differences in islet stress responses support female β cell resilienceMolecular metabolismMarch 1, 2023Brownrigg GP, Xia YH, Chu CMJ, Wang S, Chao C, Zhang JA, Skovsø S, Panzhinskiy E, Hu X, Johnson JD, et al.Cell Signalling), phospho-IRE1α (1:1000, Cat. #PA1-16927, Thermo Fisher Scientific), CHOP (1:1000, #ab11419, Abcam), β-actin (1:1000, NB600-501, Novus Biologicals). The signals were detected by secondary HRP-conjugated

(13) Ischemic Postconditioning Attenuates Myocardial Ischemia-Reperfusion-Induced Acute Lung Injury by Regulating Endoplasmic Reticulum Stress-Mediated ApoptosisBrazilian Journal of Cardiovascular SurgeryFebruary 10, 2023Aimei Li, Siyu Chen, Jianjiang Wu, Jiaxin Li, Jiang Wangincubated with anti-GRP78 (1:500, Abcam, ab21685), anti-C/EBP homologous protein (CHOP) (1:200, Abcam, ab11419), anti-caspase-12 (1:500, Abcam, ab62484) or anti-β-actin antibody (1:800, Shanghai Shenggong, d110001),

(14) An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress responseThe Journal of biological chemistryFebruary 1, 2023Amin PH, Carlson KR, Wek RC.Thermo Fisher Scientific Cat No PA5-24224), ATF4 (1:1000, In-house (34)), CHOP (DDIT3) (1:500, Abcam Cat No ab11419), total eIF2 (1:3000, CST Cat No 5324S), p-eIF2α (1:500, Abcam Cat No ab32157), GADD34 (1:2000, Proteintech

(15) Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic miceRedox biologyFebruary 1, 2023Wu D, Su S, Zha X, Wei Y, Yang G, Huang Q, Yang Y, Xia L, Fan S, Peng X.immunolabelled overnight at 4 °C with primary antibodies against G6PD (Abcam, ab993), CHOP (Abcam, ab11419), AGR2 (Abcam, ab76473), O-GlcNAC (Abcam, ab2739), glutathione (Virogen, 101-A), GRP78 (Cell Signaling,

(16) Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cellsBMC CancerDecember 30, 2022Xiaohui Liu, Bo Wu, Hong Chen, Haimei Sun, Xiaoxia Guo, Tingyi Sun, Deshan Zhou, Shu Yangmonoclonal anti-IRE1α (1:1000, CST, #3294, RRID:AB_823545), mouse monoclonal anti-DDIT3/CHOP (1:1000, Abcam, ab11419, RRID:AB_298023) and rabbit polyclonal anti-ABCC10 (1:1000, Abcam, ab107053, RRID:AB_10864747). Mouse

(17) Ubiquitination of SARS-CoV-2 ORF7a Prevents Cell Death Induced by Recruiting BclXL To Activate ER StressMicrobiology spectrumDecember 21, 2022Liu Z, Fu Y, Huang Y, Zeng F, Rao J, Xiao X, Sun X, Jin H, Li J, Yang J, et al.anti-PERK (Abcam, ab65142, 1:500), anti-phosphate eIF2α (Abcam, ab214434, 1:1,000), anti-CHOP (Abcam, ab11419, 1:2,000), anti-Caspase 3 (Abcam, ab208161, 1:1,000), anti-PARP1 (Invitrogen, 436400, 1:2,000) and rabbit

(18) Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse BrainInternational Journal of Molecular SciencesDecember 6, 2022Ryosuke Nomura, Nobumasa Takasugi, Hideki Hiraoka, Yuta Iijima, Takao Iwawaki, Yoshito Kumagai, Masatake Fujimura, Takashi Ueharaprotein (GFP) (1:200; #M048-3, Medical & Biological Laboratories, Nagoya, Japan) and anti-CHOP (1:1000; #ab11419, Abcam, Cambridge, UK). Anti-HMG-CoA reductase degradation enzyme 1 (HRD1) (1:500; #sc-130889, Santa Cruz Biotechnology

(19) C/EBP homologous protein promotes Sonic Hedgehog secretion from type II alveolar epithelial cells and activates Hedgehog signaling pathway of fibroblast in pulmonary fibrosisRespiratory ResearchDecember 1, 2022Xiaoyu Yang, Wei Sun, Xiaoyan Jing, Qian Zhang, Hui Huang, Zuojun Xurabbit anti-prosurfactant protein C antibody (Abcam, ab90716), mouse anti-CHOP (DDIT3) antibody (Abcam, ab11419), mouse anti-Sonic Hedgehog antibody (Abcam, ab135240), rabbit anti-Sonic Hedgehog (Abcam, ab73958),

(20) Sevoflurane exposure causes neuronal apoptosis and cognitive dysfunction by inducing ER stress via activation of the inositol 1, 4, 5-trisphosphate receptorFrontiers in Aging NeuroscienceOctober 20, 2022Qi Zhang, Yanan Li, Xupeng Wang, Chunping Yin, Qi Zhou, Junfei Guo, Juan Zhao, Xiaohui Xian, Zhiyong Hou, Qiujun Wang(ab264281), MFN1 (ab221661), MFN2 (ab260861), GRP75 (ab171089), p-PERK (ab192591), ATF4 (ab184909), CHOP (ab11419), cleaved caspase-3 (ab32042), cleaved caspase-9 (ab184786), Bax (ab32503) and Bcl-2 (ab32124) were

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(1)

2/9/2018CHOP (DDIT3) Antibody Andrea EstradaThis antibody was used to detect the presence of endoplasmic reticulum stress / unfolded protein response activation, specifically the IRE1 arm. This antibody used to validate gene expression of CHOP... Read Review
(1)

4/12/2016CHOP Protein Detection Via Western Blot Claire StewartCHOP is a downstream marker of the unfolded protein response (UPR). Increased expression of CHOP indicates ER stress and activation of the UPR. Therefore, being able to quantitatively measure CHOP ... Read Review

Anti-DDIT3 antibody [9C8] from Abcam

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Anti-DDIT3 antibody [9C8] from Abcam

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