Anti-Estrogen Receptor beta antibody [7B10.7] GTX70182 from GeneTex

Product Specs
ItemAnti-Estrogen Receptor beta antibody [7B10.7]
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX70182
FormatPBS, no preservative
ApplicationsWB, IP, ChIP assay
ClonalityMonoclonal
HostMouse
ReactivityHuman
TargetEstrogen Receptor beta
Conjugate/TagUnconjugated
Clone7B10.7
Antibody TypePrimary Antibodies
Quantity100 µl
IsotypeIgG1
PurityProtein G purified
ImmunogenAmino acids 1-153 of human ER-§ expressed in E. coli
Concentration1mg/ml
NCBI Full Gene Nameestrogen receptor 2
NCBI Gene AliasesER-BETA, NR3A2, ODG8, ESTRB, estrogen receptor 2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, ODG8, ESRB, Erb, ESR-BETA
Research AreaCancer, Cell Biology, Tumor Markers
Gene NameESR2
Molecular Weight59

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) Insights into the Role of Estrogen Receptor β in Triple-Negative Breast CancerCancersJune 5, 2020Sellitto A, D'Agostino Y, Alexandrova E, Lamberti J, Pecoraro G, Memoli D, Rocco D, Coviello E, Giurato G, Nassa G, et al.

(2) Estrogen Receptor-β Modulation of the ERα-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast CancerHormones & cancerAugust 1, 2017Lu W, Katzenellenbogen BS.Upstate); ERα (HC-20, Santa Cruz); ERβ antibodies were a combination of CWK-F12 (produced in our lab) (25), GTX70182 (GeneTex), GR40 (Calbiochem), and PA1-311 (Af nity Bioreagents); N-CoR (sc-1609, Santa Cruz); and SMRT

(3) Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificityMolecular and cellular endocrinologyJanuary 15, 2017Nelson AW, Groen AJ, Miller JL, Warren AY, Holmes KA, Tarulli GA, Tilley WD, Katzenellenbogen BS, Hawse JR, Gnanapragasam VJ, et al.

(4) Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activationFertility and sterilityMay 1, 2016Monsivais D, Dyson MT, Yin P, Navarro A, Coon JS Th, Pavone ME, Bulun SE.μg each of an ERβ antibody mixture (CWK-F12 (28), Pierce, Waltham, MA, PA1-311; GeneTex, Irvine, CA, GTX70182; Calbiochem, Billerica, MA, GR-40) or IgG (Sigma) overnight at 4°C. Dynal Beads (Life Technologies)

(5) ERβ- and prostaglandin E2-regulated pathways integrate cell proliferation via Ras-like and estrogen-regulated growth inhibitor in endometriosisMolecular endocrinology (Baltimore, Md.)August 1, 2014Monsivais D, Dyson MT, Yin P, Coon JS, Navarro A, Feng G, Malpani SS, Ono M, Ercan CM, Wei JJ, et al.

(6) Preferential estrogen receptor β ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagyMolecular cancer therapeuticsJuly 1, 2014Ruddy SC, Lau R, Cabrita MA, McGregor C, McKay BC, Murphy LC, Wright JS, Durst T, Pratt MA.

(7) Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogensFASEB journal : official publication of the Federation of American Societies for Experimental BiologyNovember 1, 2013Jiang Y, Gong P, Madak-Erdogan Z, Martin T, Jeyakumar M, Carlson K, Khan I, Smillie TJ, Chittiboyina AG, Rotte SC, et al.

(8) Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulatorsMolecular systems biologyJune 18, 2013Madak-Erdogan Z, Charn TH, Jiang Y, Liu ET, Katzenellenbogen JA, Katzenellenbogen BS.antibodies were a combination with equal parts of CWK-F12 (produced in our lab (Choi et al, 2001)), GTX70182 (GeneTex), GR40 (Calbiochem), and PA1-311 (Affinity Bioreagents); SRC3 antibody SC-9119 (Santa Cruz Biotechnology

(9) Induction of quinone reductase by tamoxifen or DPN protects against mammary tumorigenesisFASEB journal : official publication of the Federation of American Societies for Experimental BiologyOctober 1, 2012Krishnamurthy N, Hu Y, Siedlak S, Doughman YQ, Watanabe M, Montano MM.

(10) Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2Breast cancer research and treatmentOctober 1, 2011Paruthiyil S, Cvoro A, Tagliaferri M, Cohen I, Shtivelman E, Leitman DC.

(11) Estrogen receptor beta binds to and regulates three distinct classes of target genesThe Journal of biological chemistryJuly 16, 2010Vivar OI, Zhao X, Saunier EF, Griffin C, Mayba OS, Tagliaferri M, Cohen I, Speed TP, Leitman DC.

(12) Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethaneEndocrinologyApril 1, 2010Vivar OI, Saunier EF, Leitman DC, Firestone GL, Bjeldanes LF.

(13) Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selectionMolecular endocrinology (Baltimore, Md.)January 1, 2010Charn TH, Liu ET, Chang EC, Lee YK, Katzenellenbogen JA, Katzenellenbogen BS.

(14) Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin bindingMolecular endocrinology (Baltimore, Md.)May 1, 2008Chang EC, Charn TH, Park SH, Helferich WG, Komm B, Katzenellenbogen JA, Katzenellenbogen BS.

(15) Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extractEndocrinologyFebruary 1, 2007Cvoro A, Paruthiyil S, Jones JO, Tzagarakis-Foster C, Clegg NJ, Tatomer D, Medina RT, Tagliaferri M, Schaufele F, Scanlan TS, et al.

(16) Distinct roles of unliganded and liganded estrogen receptors in transcriptional repressionMolecular cellFebruary 17, 2006Cvoro A, Tzagarakis-Foster C, Tatomer D, Paruthiyil S, Fox MS, Leitman DC.

(17) Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and betaMolecular biology of the cellMarch 1, 2004Tee MK, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ, Yamamoto KR, Leitman DC.

(18) Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damageMolecular endocrinology (Baltimore, Md.)July 1, 2003Bianco NR, Perry G, Smith MA, Templeton DJ, Montano MM.

(19) Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptorThe Journal of biological chemistryApril 26, 2002Burakov D, Crofts LA, Chang CP, Freedman LP.

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Anti-Estrogen Receptor beta antibody [7B10.7]

Anti-Estrogen Receptor beta antibody [7B10.7] from GeneTex

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GeneTex

Citations (19)

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Anti-Estrogen Receptor beta antibody [7B10.7] from GeneTex

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