A2B5 Antibody MAB1416 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemA2B5 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB1416
ApplicationsFlow Cytometry, Immunocytochemistry, CyTOF-ready
Quantity100 ug (also 25 ug)
ReactivityHuman, Mouse, Rat, Chicken
HostMouse
Conjugate/TagUnconjugated
Clone105
IsotypeIgM
TargetA2B5
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenEmbryonic chicken retinal cells
ConcentrationLYOPH
PurityIgM-specific Affinity-purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Recognizes the A2B5 cell surface ganglioside epitope found on type II astrocytes, cells involved in gliogenesis, and cells committed to the oligodendrocyte lineage (1-4)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistanceCell reportsSeptember 26, 2023Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo FT, Yoshida Y, Kutsukake N, Mariani JN, Windrem MS, Chandler-Militello D, et al.

(2) Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature OligodendrocytesCellular and molecular neurobiologyJuly 1, 2023Ye D, Wang Q, Yang Y, Chen B, Zhang F, Wang Z, Luan Z.#ab6320, Abcam, Cambridge, Cambridgeshire, UK, RRID: AB_308832) antibodies. Mouse anti-A2B5 (1:50; Cat. #MAB1416, R&D Systems, Minneapolis, MN, USA, RRID: AB_357687), rabbit anti-OLIG2 (1:300; Cat. #AB9610, Millipore,

(3) Intrauterine desensitization enables long term survival of human oligodendrocyte progenitor cells without immunosuppressioniScienceMay 19, 2023Dou Ye, Suqing Qu, Yinxiang Yang, Zhaoyan Wang, Qian Wang, Weipeng Liu, Fan Zhang, Qian Guan, Xiaohua Wang, Jing Zang, et al.in 24-well plates and immunofluorescence staining was performed using mouse anti-A2B5 (1:50; Cat. #MAB1416, R&D Systems, Minneapolis, MN, USA, RRID: AB_357687), rabbit anti-platelet-derived growth factor (PDGF)

(4) Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosisGliaOctober 1, 2022Titus HE, Xu H, Robinson AP, Patel PA, Chen Y, Fantini D, Eaton V, Karl M, Garrison ED, Rose IVL, et al.at 4°C using the following specified antibodies: early glial progenitors (A2B5 1:100; R&D Systems #MAB1416), late glial progenitors (PDGFRα 1:50; Millipore #CBL1366 & NG2 1:200; Millipore #AB5320), pre‐OL to

(5) Identifying the functions of two biomarkers in human oligodendrocyte progenitor cell developmentJournal of Translational MedicineDecember 1, 2021Haipeng Zhou, Ying He, Zhaoyan Wang, Qian Wang, Caiyan Hu, Xiaohua Wang, Siliang Lu, Ke Li, Yinxiang Yang, Zuo Luananti-NG2 (1:50, Cat. #ab83178, Abcam, Cambridge, Cambridgeshire, UK) and mouse anti-A2B5 (1:50, Cat. #MAB1416, R&D Systems, Minneapolis, MN, USA) antibodies were used to identify hOPCs. Cell nuclei were stained

(6) BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytesAutophagyOctober 1, 2021Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, Chamling X, Tian S, Sullivan MLG, Calderon MJ, et al.

(7) Donor cell memory confers a metastable state of directly converted cellsCell stem cellJuly 1, 2021Kim KP, Li C, Bunina D, Jeong HW, Ghelman J, Yoon J, Shin B, Park H, Han DW, Zaugg JB, et al.

(8) Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitorOncogeneMarch 1, 2019Zepecki JP, Snyder KM, Moreno MM, Fajardo E, Fiser A, Ness J, Sarkar A, Toms SA, Tapinos N.

(9) Lineage-Specific Differentiation Is Influenced by State of Human PluripotencyCell reportsApril 4, 2017Lee JH, Laronde S, Collins TJ, Shapovalova Z, Tanasijevic B, McNicol JD, Fiebig-Comyn A, Benoit YD, Lee JB, Mitchell RR, et al.

(10) Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's DiseaseStem cells translational medicineJanuary 1, 2017Cha MY, Kwon YW, Ahn HS, Jeong H, Lee YY, Moon M, Baik SH, Kim DK, Song H, Yi EC, et al.

(11) Differentiation of Spiral Ganglion-Derived Neural Stem Cells into Functional Synaptogenetic NeuronsStem cells and developmentMay 15, 2016Li X, Aleardi A, Wang J, Zhou Y, Andrade R, Hu Z.immunofluorescence using anti-neural adhesion molecules (NCAM, sc-106; SCBT), anti-GFAP (sc-6170; SCBT), anti-A2B5 (MAB1416; R&D systems), anti-Sox2 (ab107156; Abcam), and anti-nestin (RAT-401; DSHB) antibodies. For immunofluorescence

(12) Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migrationThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 7, 2015Moyon S, Dubessy AL, Aigrot MS, Trotter M, Huang JK, Dauphinot L, Potier MC, Kerninon C, Melik Parsadaniantz S, Franklin RJ, et al.[rabbit polyclonal, 1:200; catalog #ab21667 (RRID:AB_446468), Abcam], anti-A2B5 [mouse IgM, 1:5; catalog #MAB1416 (RRID:AB_357687), R&D Systems], anti O4 (mouse monoclonal IgM, 1:5; hybridoma was a gift from I. Sommer,

(13) Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineagePloS oneJanuary 1, 2014Leite C, Silva NT, Mendes S, Ribeiro A, de Faria JP, Lourenço T, dos Santos F, Andrade PZ, Cardoso CM, Vieira M, et al.

(14) Generation of neuronal progenitor cells in response to tumors in the human brainStem CellsJanuary 1, 2014Macas J, Ku MC, Nern C, Xu Y, Bühler H, Remke M, Synowitz M, Franz K, Seifert V, Plate KH, et al.

(15) Characterization of oligodendroglial populations in mouse demyelinating disease using flow cytometry: clues for MS pathogenesisPloS oneJanuary 1, 2014Robinson AP, Rodgers JM, Goings GE, Miller SD.

(16) Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cellsNature biotechnologyMay 1, 2013Najm FJ, Lager AM, Zaremba A, Wyatt K, Caprariello AV, Factor DC, Karl RT, Maeda T, Miller RH, Tesar PJ.

(17) In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formationStem CellsMarch 1, 2012Werbowetski-Ogilvie TE, Morrison LC, Fiebig-Comyn A, Bhatia M.

(18) Neurosteroid Hormones Modulate the Differentiation of Adult Human Multipotent Mesenchymal Stromal CellsJournal of Stem Cell Research & TherapyJanuary 1, 2012B. I. Tiftikcioglu C. M. RicePROG or DHT and stained for early oligodendroglial cell markers. Cells were doublestained for A2B5 (MAB1416, R&D Systems, UK, 2µg/ml) and nestin (MAB5326, Chemicon, UK, 1:400). A2B5 staining was performed live;

(19) Human glial-restricted progenitors survive, proliferate, and preserve electrophysiological function in rats with focal inflammatory spinal cord demyelinationGliaMarch 1, 2011Piotr Walczak et al.Carpinteria, CA); Myelin basic protein (MBP) (1:500, MCA409S; AbD Serotec; Kidlington, Oxford). A2B5 (MAB1416, R&D Systems), PDGFRalpha (MAB1264, R&D Systems), Nestin (MAB5326, Millipore), PSA-NCAM (MAB5324, Millipore),

(20) Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascadeProceedings of the National Academy of Sciences of the United States of AmericaMarch 23, 2010Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, et al.

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A2B5 Antibody

A2B5 Antibody

A2B5 Antibody

A2B5 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (29)

Reviews

A2B5 Antibody from R&D Systems, a Bio-Techne Brand

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