Fig 1: TT-2 enhanced the integrity of intestinal epithelium of mice after 14 Gy ABI. (A) Representative Chga-stained sections and quantification of Chga+ cells in crypt of small intestine after 14 Gy ABI and different treatments (**p < 0.01, scale bar = 100 µm). Three mice from each group were used. (B) Representative lysozyme-stained sections and quantification of lysozyme+ cells in crypt of small intestine after 14 Gy ABI and different treatments (**p < 0.01, scale bar = 100 µm). Three mice from each group were used. (C) Representative Muc2-stained sections and quantification of Muc2+ cells in crypt of small intestine after 14 Gy ABI and different treatments (**p < 0.01, scale bar = 100 µm). Three mice from each group were used. (D) qPCR for differentiation-related gene expression in mouse intestinal epithelial cells after 10 Gy irradiation with or without TT-2 treatment for 48 h (**p < 0.01). (E) The FITC-Dextran level in the serum of mice on day 4 after 14 Gy ABI and treatment with water with or without TT-2 from day -2 to 4 (**p < 0.01).