IL-15 Antibody AF447 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-15 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF447
NCBI Gene AliasesIL-15
ApplicationsWestern Blot, Immunohistochemistry, Neutralization
Conjugate/TagUnconjugated
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
Quantity100 ug (also 25 ug)
TargetIL-15
HostGoat
NCBI Full Gene Nameinterleukin 15
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant mouse IL-15, Asn49-Ser162, Accession # P48346
ConcentrationLYOPH
PurityAntigen Affinity-purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse IL-15 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human IL-15 is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cellsCellular & molecular immunologySeptember 1, 2021Yu M, Pan H, Che N, Li L, Wang C, Wang Y, Ma G, Qian M, Liu J, Zheng M, et al.anti-IL-15 antibody was purchased from R&D Systems. An equivalent of 15 μg/mL mouse anti-IL-15 antibody (catalog AF447; R&D Systems) was injected intraperitoneally in a volume of 100 μL one day prior to therapy and at 4-day

(2) IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in miceScientific ReportsDecember 1, 2020Xianghong Li, Wanchang Cui, Lisa Hull, Li Wang, Tianzheng Yu, Mang Xiaoanti-IFN-γ antibody, Abcam ab9657; anti-IL-15 antibody, Abcam ab34674; anti-TNF-α antibody, R&D systems AF447; anti-IL-12/IL-35 p35 Antibody, R &D systems MAB6688; and rabbit IgG isotype control antibody, Abcam

(3) DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T CellsCell reportsDecember 10, 2019Suhail A, Rizvi ZA, Mujagond P, Ali SA, Gaur P, Singh M, Ahuja V, Awasthi A, Srikanth CV.

(4) TCR-pMHC encounter differentially regulates transcriptomes of tissue-resident CD8 T cellsEuropean journal of immunologyJanuary 1, 2018Yoshizawa A, Bi K, Keskin DB, Zhang G, Reinhold B, Reinherz EL.rabbit anti-TGF-β (Cat. # ab66043), from Bio-Techne (Minneapolis, MN): purified goat anti-IL-15 (Cat. # AF447), and Novus Biologicals (Littleton, CO): Alexa Flour 488-conjugated anti-P2X7/P2RX7 (clone Hano43).

(5) ESAT-6-dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivoThe Journal of clinical investigationJune 1, 2016Kupz A, Zedler U, Stäber M, Perdomo C, Dorhoi A, Brosch R, Kaufmann SH.provided by I. Förster, University of Bonn, Bonn, Germany); anti–IFN-γ (clone XMG1.2); anti–IL-15 (catalog AF447; R&D Systems); or control rat IgG was injected i.p. weekly in a volume of 200 μl. Statistics. Flow cytometric

(6) Transcription factor KLF2 regulates homeostatic NK cell proliferation and survivalProceedings of the National Academy of Sciences of the United States of AmericaMay 10, 2016Rabacal W, Pabbisetty SK, Hoek KL, Cendron D, Guo Y, Maseda D, Sebzda E.

(7) IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infectionMucosal immunologySeptember 1, 2014Jayaraman A, Jackson DJ, Message SD, Pearson RM, Aniscenko J, Caramori G, Mallia P, Papi A, Shamji B, Edwards M, et al.

(8) Combination of TACI-IgG and anti-IL-15 treats murine lupus by reducing mature and memory B cellsCellular immunologyMay 1, 2014Ma N, Xiao H, Marrero B, Xing C, Wang X, Zheng M, Han G, Chen G, Hou C, Shen B, et al.

(9) Maltose-binding protein fusion allows for high level bacterial expression and purification of bioactive mammalian cytokine derivativesPloS oneJanuary 1, 2014Pennati A, Deng J, Galipeau J.

(10) Blockade of IL-15 activity inhibits microglial activation through the NFkappaB, p38, and ERK1/2 pathways, reducing cytokine and chemokine releaseGliaFebruary 1, 2010Gomez-Nicola D, Valle-Argos B, Nieto-Sampedro M.

(11) IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentationThe Journal of experimental medicineMay 12, 2008Mortier E, Woo T, Advincula R, Gozalo S, Ma A.BAF447 antibody (R&D Systems) as the detection reagent. For IL-15–IL-15Rα complex detection, anti–IL-15 AF447 antibody (R&D Systems) was used as the capture antibody and anti–IL-15Rα (from the Duo-set kit) as the

(12) A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complexBloodMarch 1, 2007Rafei M, Wu JH, Annabi B, Lejeune L, François M, Galipeau J.

(13) The Absence of Platelet-Derived Growth Factor-B in Circulating Cells Promotes Immune and Inflammatory Responses in Atherosclerosis-Prone ApoE−/− MiceThe American Journal of PathologySeptember 1, 2005Jingjing Tang, Koichi Kozaki, Andrew G. Farr, Paul J. Martin, Per Lindahl, Christer Betsholtz, Elaine W. Rainesantibody (m-20) from Santa Cruz Biotechnology (Santa Cruz, CA); goat anti-mouse IL-15 polyclonal antibody (AF447; R&D Systems, Minneapolis, MN); rabbit anti-human CD3 polyclonal antibody (A0452; DAKO, Carpinteria,

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IL-15 Antibody

IL-15 Antibody

IL-15 Antibody

IL-15 Antibody

IL-15 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-15 Antibody from R&D Systems, a Bio-Techne Brand

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