Fig 1: Temporal changes in LDL-EV hemostatic protein composition in post-AMI patients with adverse and reverse LV remodeling. Coagulation proteins (VWF, SerpinC1) and fibrinolytic protein (plasminogen) levels and their ratios (VWF:Plasminogen, SerpinC1:Plasmingen) in LDL-EVs of 198 post-AMI patients at baseline and after 1 and 6 month follow-up. (A) A diagram illustrating the studied hemostatic proteins in LDL-EVs. (B–F) Differences between baseline and follow-up measurements were established by Wilcoxon signed-ranked test (horizontal statistical bar). Differences in the three protein levels and the protein ratios between patients with adverse LV remodeling and reverse LV remodeling were established by Mann–Whitney U test (vertical statistical bar). Data are presented as mean ± SEM.