Phospho-GSK-3 alpha/beta (S21/S9) Antibody AF1590 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemPhospho-GSK-3 alpha/beta (S21/S9) Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF1590
ApplicationsWestern Blot, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
HostRabbit
TargetGSK-3 alpha/beta
ReactivityHuman, Mouse, Rat
IsotypeIgG
ClonalityPolyclonal
Modificationsp ser9
ImmunogenPhosphopeptide containing GSK-3 beta S9 site
ConcentrationLYOPH
PurityAntigen and protein A Affinity-purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
NCBI Full Gene Nameglycogen synthase kinase 3 beta
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human, mouse, and rat GSK-3 beta when phosphorylated at S9, and human, mouse, and rat GSK-3 alpha when phosphorylated at S21

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein MarkersBiosensorsAugust 27, 2023Meah A, Vedarethinam V, Bronstein R, Gujarati N, Jain T, Mallipattu SK, Li Y, Wang J.

(2) Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cellsCell death & diseaseApril 13, 2023Li S, Pritchard DM, Yu LG.

(3) Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heartPloS oneJanuary 1, 2021Tang Y, Kline KT, Zhong XS, Xiao Y, Lian H, Peng J, Liu X, Powell DW, Tang G, Li Q.polyclonal (Cat. # OSB00017W, 1:1000)(Thermo Fisher Scientific), anti-GSK-3β rabbit polyclonal (Cat. # AF1590, 1:1000)(R&D Systems, Minneapolis, MN), anti-BCL-2 rabbit polyclonal (Cat. # 3498S, 1:1000), anti-phospho-AKT

(4) Cathepsin V suppresses GATA3 protein expression in luminal A breast cancerBreast Cancer ResearchDecember 9, 2020Naphannop Sereesongsaeng, Sara H. McDowell, James F. Burrows, Christopher J. Scott, Roberta E. Burdenmouse monoclonal Akt (BD Transduction Laboratories, P78020), rabbit polyclonal pSer9 GSK-3β (BioTechne, AF1590), mouse monoclonal GSK-3β (BioTechne, MAB25063) and mouse monoclonal FLAG M2 (Sigma-Aldrich, F3165).

(5) Chemotherapy induced PRL3 expression promotes cancer growth via plasma membrane remodeling and specific alterations of caveolae-associated signalingCell communication and signaling : CCSAugust 29, 2018Csoboz B, Gombos I, Tatrai E, Tovari J, Kiss AL, Horvath I, Vigh L.USA; 1:1000, 5676) anti-phospho GSK3β Ser9 (R&D Systems Inc., Minneapolis, Minnesota, USA; 1:1000, AF1590), anti-Rac1 (EMD Millipore, Billerica, Massachusetts, USA; 1:1000, 05–389), anti-AKT (Cell Signaling Technology

(6) HYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling PathwayPloS oneJanuary 1, 2015Chiu CT, Liao CK, Shen CC, Tang TK, Jow GM, Wang HS, Wu JC.

(7) Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 responsePloS oneJanuary 1, 2014Lutay N, Håkansson G, Alaridah N, Hallgren O, Westergren-Thorsson G, Godaly G.Membranes were then incubated on a shaker overnight at 4°C with rabbit anti-human p-GSK-3α/β (1∶500; AF1590, R&D systems, Denmark), GSK-3α/β (1∶250; AF2157, R&D systems), p-CREB (1∶1000; #9198 Cell Signalling

(8) Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathwaysJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchDecember 1, 2010Kitase Y, Barragan L, Qing H, Kondoh S, Jiang JX, Johnson ML, Bonewald LF.

(9) Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylationThe Journal of experimental medicineApril 12, 2010Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, et al.

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Phospho-GSK-3 alpha/beta (S21/S9) Antibody

Phospho-GSK-3 alpha/beta (S21/S9) Antibody

Phospho-GSK-3 alpha/beta (S21/S9) Antibody

Phospho-GSK-3 alpha/beta (S21/S9) Antibody

Phospho-GSK-3 alpha/beta (S21/S9) Antibody

Phospho-GSK-3 alpha/beta (S21/S9) Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Phospho-GSK-3 alpha/beta (S21/S9) Antibody from R&D Systems, a Bio-Techne Brand

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