Mouse VLDLR Antibody AF2258 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse VLDLR Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF2258
ApplicationsBlocking,IHC fixed frozen,IHC Paraffin-embedded,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHamster,Human,Mouse
IsotypeIgG
TargetVLDLR
HostGoat
Quantity100 ug (also 25 ug)
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse VLDL R, Thr25-Ala798, Accession # AAA59384
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namevery low density lipoprotein receptor

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Deletion of neuronal Idol ameliorates Alzheimer's disease-related pathologies via APOE receptorsAlzheimers DementDecember 12, 2025Hande Karahan, Kelly Hartigan, Md Mamun Al-Amin, Sutha K. John, Brianne McCord, H. R. Sagara Wijeratne, Dominic J. Acri, Daniel C. Smith, Luke C. Dabin, Hannah M. Rondon Cordero, et al.JM‐3839‐100, 1:2000), APOE (Abclonal, A16344, 1:1000), APOER2 (Abcam, ab108208, 1:1000), VLDLR (R&D Systems, AF2258, 1:1000), or β‐actin (Sigma, A1978, 1:20,000). Signals were visualized using a chemiluminescence detection

(2) A sexually dimorphic hepatic cycle of periportal VLDL generation and subsequent pericentral VLDLR-mediated re-uptakeNature CommunicationsSeptember 28, 2024Tomaz Martini, Cédric Gobet, Andrea Salati, Jérôme Blanc, Aart Mookhoek, Michael Reinehr, Graham Knott, Jessica Sordet-Dessimoz, Felix NaefPBS before loading wet on the automated device. The primary antibody, goat anti-VLDLR (R&D Systems AF2258, diluted 1: 50 in 1% BSA in 1x PBS) was incubated 1 h at 37 °C. After incubation with goat Immpress

(3) SIRT1 regulates hepatic vldlr levelsCell communication and signaling : CCSMay 28, 2024Peyman M, Babin-Ebell A, Rodríguez-Rodríguez R, Rigon M, Aguilar-Recarte D, Villarroya J, Planavila A, Villarroya F, Palomer X, Barroso E, et al.(ab189494, Abcam), TRB3 (sc-365,842, Santa Cruz Biotechnology Inc.), tubulin (T6074, Sigma) or VLDLR (AF2258, R&D Systems). Statistical analysis Results are expressed as the mean ± SEM. Significant differences

(4) Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stressBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieDecember 1, 2023Peyman M, Barroso E, Turcu AL, Estrany F Jr, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde ÁM, et al.(sc-365842, Santa Cruz Biotechnology Inc.), vinculin (sc-25336, Santa Cruz Biotechnology Inc.), VLDLR (AF2258, R&D Systems). Signal acquisition was performed using the Amersham Imager 680 apparatus and quantification

(5) Very low-density lipoprotein receptor increases in a liver-specific manner due to protein deficiency but does not affect fatty liver in miceScientific reportsApril 13, 2021Oshio Y, Hattori Y, Kamata H, Ozaki-Masuzawa Y, Seki A, Tsuruta Y, Takenaka A.previously38. Anti-VLDLR antibody (Novus Biologicals, NBP1-78162, 1:600 dilution for Fig. 3BD; R&D systems, AF2258, 1:2000 dilution for Figs. 3A,C and S3), β-actin antibody (Abcam, ab6276, 1:500 dilution), and anti-α-tubulin

(6) Disabled 1 Is Part of a Signaling Pathway Activated by Epidermal Growth Factor ReceptorInternational journal of molecular sciencesFebruary 9, 2021Dlugosz P, Teufl M, Schwab M, Kohl KE, Nimpf J.1:1000, IP" ApoER2,Ab186,Produced in the lab,IP ApoER2,Ab 20,Produced in the lab,WB 1:5000 VLDLR,AF2258,"R&D Systems (Minneapolis, MN, USA)",WB 1:1000 p-Tyr (PY99),sc-7020,"Santa Cruz Biotechnology (Dallas,

(7) Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific MannerThe Journal of neuroscience : the official journal of the Society for NeuroscienceOctober 21, 2020Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M.rabbit monoclonal anti-Nrp1 (ab81321, Abcam, RRID:AB_1640739; WB 1:1000, IHC 1:500), goat anti-VLDLR (AF2258, R&D Systems, RRID:AB_2288612; WB 1:1000, IHC 1:500, IP 1:300), rabbit monoclonal anti-ApoER2 (ab108208, Abcam,

(8) The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic NeocortexThe Journal of neuroscience : the official journal of the Society for NeuroscienceSeptember 30, 2020Ogino H, Nakajima T, Hirota Y, Toriuchi K, Aoyama M, Nakajima K, Hattori M.AB_2253745, 1:1000 for IHC), goat anti-PDGFR a (AF1062, RRID:AB_2236897, 1:500 for IHC), and goat VLDLR (AF2258, RRID:AB_2288612, 1:500 for IHC) from R&D Systems; rat anti-Dab1 (D355-3 and D354-3, 1:1000 for WB)

(9) SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2Cell communication and signaling : CCSSeptember 10, 2020Barroso E, Rodríguez-Rodríguez R, Zarei M, Pizarro-Degado J, Planavila A, Palomer X, Villarroya F, Vázquez-Carrera M.MA), GAPDH (MAB374) (Merck Millipore), CD36 (NB400–144) (Novus Biologicals, Centennial, CO), VLDLR (AF2258) (R&D Systems, Minneapolis, MN). Detection was performed with the Western Lightning™® Plus-ECL chemiluminescence

(10) VLDLR is not essential for reelin-induced neuronal aggregation but suppresses neuronal invasion into the marginal zoneDevelopment (Cambridge, England)June 15, 2020Hirota Y, Nakajima K.Laboratories). The following primary antibodies were used in this study: VLDLR (goat, 1:600, R&D Systems, AF2258), Tbr1 (rabbit, 1:1000, gift from R. Hevner, University of California, USA), reelin (goat, 1:200, R&D Systems

(11) A low-carbohydrate ketogenic diet induces the expression of very-low-density lipoprotein receptor in liver and affects its associated metabolic abnormalitiesNPJ science of foodJanuary 1, 2019Okuda T.analyses were conducted according to a previously reported method16,31 using an anti-VLDLR antibody (AF2258; Bio-Techne, Minneapolis, MN, USA). Lipoprotein analysis The triglyceride and cholesterol profiles

(12) Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging MicroscopyFrontiers in molecular neuroscienceJanuary 1, 2019Dlugosz P, Tresky R, Nimpf J.Epitope,Catalog number,Company/Reference,Dilution VLDLR,AF2258,R&D Systems,"WB 1:2,000" VLDLR (6A6),sc-18824,Santa Cruz Biotechnology,IP VLDLR,Ab74,Strasser et al.

(13) Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver diseaseMolecular metabolismFebruary 1, 2018Zarei M, Barroso E, Palomer X, Dai J, Rada P, Quesada-López T, Escolà-Gil JC, Cedó L, Zali MR, Molaei M, et al.antibodies against VLDLR (sc-18824), Nrf2 (sc-722), Nqo1 (sc-393736), ATF4 (sc-200) (Santa Cruz), VLDLR (AF2258) (R&D system), eIF2α (9722), phospho-eIF2α (Ser51) (9721), IgG control (2729S) (Cell Signaling Technology

(14) Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical PathwayFrontiers in cellular neuroscienceJanuary 1, 2018Dairaghi L, Flannery E, Giacobini P, Saglam A, Saadi H, Constantin S, Casoni F, Howell BW, Wray S.

(15) Mathematical model of early Reelin-induced Src family kinase-mediated signalingPloS oneJanuary 1, 2017Hass H, Kipkeew F, Gauhar A, Bouché E, May P, Timmer J, Bock HH.1:1000), rabbit anti-ApoER2 (EPR3326) (Abcam ab108208, 1:1000), goat anti-Vldlr antibody (R&D systems AF2258, 1:500), mouse anti-Reelin G10 [33], 1:2000) and respective secondary HRP-coupled antibodies: anti-mouse IgG

(16) Pericyte loss influences Alzheimer-like neurodegeneration in miceNature communicationsJanuary 1, 2013Sagare AP, Bell RD, Zhao Z, Ma Q, Winkler EA, Ramanathan A, Zlokovic BV.Argraves, Medical University of South Carolina), very low-density lipoprotein receptor (R&D Systems; AF2258) and low-density lipoprotein receptor (R&D Systems; AF2255)6. Cy3-Aβ40 (1 μM) internalization and lysosomal

(17) Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formationThe Journal of cell biologyJune 11, 2012Lutter S, Xie S, Tatin F, Makinen T.

(18) Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis developmentArteriosclerosis, thrombosis, and vascular biologyFebruary 1, 2012Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, et al.(Santa Cruz Biotechnology, CA, #sc20991), LDLR (Cayman Chemical, MI, #1007665), VLDL receptors, SR-A1 (R&D Systems, MN, #AF2258, 1797), CD36 (Lifespan Bioscience, WA, #LS-B662/10019), SR-B1, -B2, ABCG1 (Novus Biologicals, CO, #NB400 –101

(19) miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesisDevelopment (Cambridge, England)January 1, 2012Rebustini IT, Hayashi T, Reynolds AD, Dillard ML, Carpenter EM, Hoffman MP.

(20) Exercise during pregnancy mitigates Alzheimer-like pathology in mouse offspringFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJanuary 1, 2012Herring A, Donath A, Yarmolenko M, Uslar E, Conzen C, Kanakis D, Bosma C, Worm K, Paulus W, Keyvani K.

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VLDLR Antibody

VLDLR Antibody

VLDLR Antibody

VLDLR Antibody

VLDLR Antibody

Mouse VLDLR Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (23)

Reviews

Mouse VLDLR Antibody from R&D Systems, a Bio-Techne Brand

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