InVivoMab anti-mouse IL-3 BE0282-R001mg from Bio X Cell

Product Specs
ItemInVivoMab anti-mouse IL-3
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0282-R001mg
Quantity1 mg
Applicationsin vivo IL-3 neutralization, in vitro IL-3 neutralization, in vivo IL-3 receptor stimulation (as a complex with IL-3), ELISA, Flow cytometry
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetIL-3
IsotypeIgG1
CloneMP2-8F8
Hostrat
NCBI Full Gene Nameinterleukin 3
NCBI Gene AliasesBPA, Csfmu, HCGF, Il-3, MCGF, PSF
ClonalityMonoclonal
ImmunogenCOS-expressed, recombinant mouse IL-3
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 6.5, Contains no stabilizers or preservatives
Research AreaCytokine and Chemokine, Immunology, Innate Immunity, Neuroscience

Specifications/Features

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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Bio X Cell

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

Company Profile

Website: bioxcell.com

(1) Melanoma induced immunosuppression is mediated by hematopoietic dysregulationOncoimmunologyJanuary 1, 2018Kamran N, Li Y, Sierra M, Alghamri MS, Kadiyala P, Appelman HD, Edwards M, Lowenstein PR, Castro MG.

(2) IL-3 contributes to development of lupus nephritis in MRL/lpr miceKidney internationalNovember 1, 2015Renner K, Hermann FJ, Schmidbauer K, Talke Y, Rodriguez Gomez M, Schiechl G, Schlossmann J, Brühl H, Anders HJ, Mack M.

(3) The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenanceJournal of immunology (Baltimore, Md. : 1950)May 1, 2015Li Y, Qi X, Liu B, Huang H.

(4) Sequential engagement of FcεRI on Mast Cells and Basophil Histamine H(4) Receptor and FcεRI in Allergic RhinitisJournal of immunology (Baltimore, Md. : 1950)January 15, 2013Shiraishi Y, Jia Y, Domenico J, Joetham A, Karasuyama H, Takeda K, Gelfand EW.

(5) Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascadeNature communicationsJanuary 1, 2013Leyva-Castillo JM, Hener P, Michea P, Karasuyama H, Chan S, Soumelis V, Li M.

(6) Antibodies and IL-3 support helminth-induced basophil expansionProceedings of the National Academy of Sciences of the United States of AmericaSeptember 11, 2012Herbst T, Esser J, Prati M, Kulagin M, Stettler R, Zaiss MM, Hewitson JP, Merky P, Verbeek JS, Bourquin C, et al.

(7) IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleenJournal of immunology (Baltimore, Md. : 1950)March 1, 2009Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting KD, Wang D, Huang H.

(8) CD48 is an allergen and IL-3-induced activation molecule on eosinophilsJournal of immunology (Baltimore, Md. : 1950)July 1, 2006Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, Levi-Schaffer F.

(9) Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasiteThe Journal of experimental medicineAugust 16, 2004Min B, Prout M, Hu-Li J, Zhu J, Jankovic D, Morgan ES, Urban JF Jr, Dvorak AM, Finkelman FD, LeGros G, et al.

(10) T cell-derived IL-3 induces the production of IL-4 by non-B, non-T cells to amplify the Th2-cytokine response to a non-parasite antigen in Schistosoma mansoni-infected miceJournal of immunology (Baltimore, Md. : 1950)February 15, 1996Kullberg MC, Berzofsky JA, Jankovic DL, Barbieri S, Williams ME, Perlmann P, Sher A, Troye-Blomberg M.

(11) Development of rat anti-mouse interleukin 3 monoclonal antibodies which neutralize bioactivity in vitroJournal of immunology (Baltimore, Md. : 1950)January 1, 1988Abrams JS, Pearce MK.

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InVivoMab anti-mouse IL-3

InVivoMab anti-mouse IL-3

InVivoMab anti-mouse IL-3 from Bio X Cell

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Bio X Cell

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InVivoMab anti-mouse IL-3 from Bio X Cell

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