InVivoMAb anti-mouse CD200 (OX2) BE0299-R100mg from Bio X Cell

Description

Bio X Cell InVivoMAb anti-mouse CD200 (OX2) Monoclonal Antibody has the following reported applications: in vivo CD200 blockade, in vitro CD200 blockade, Immunohistochemistry (frozen), Immunofluorescence, Flow cytometry. It features greater than 95% purity, ultra-low endotoxin levels, and are preservative, stabilizer, and carrier protein-free

Product Specs
ItemInVivoMAb anti-mouse CD200 (OX2)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0299-R100mg
Quantity100 mg
Applicationsin vivo CD200 blockade, in vitro CD200 blockade, Immunohistochemistry (frozen), Immunofluorescence, Flow cytometry
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetCD200
IsotypeIgG2a, κ
CloneOX-90
Hostrat
NCBI Full Gene NameCD200 molecule
NCBI Gene AliasesMox2, OX2
ClonalityMonoclonal
ImmunogenFusion protein consisting of mouse CD200 (extracellular region) and rat CD4 (domains 3 and 4)
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaImmune Checkpoint Protein, Immunology, Neuroscience, Tumor Antigens

Specifications/Features

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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Bio X Cell

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

Company Profile

Website: bioxcell.com

(1) CD200 promotes immunosuppression in the pancreatic tumor microenvironmentJournal for immunotherapy of cancerJune 1, 2020Choueiry F, Torok M, Shakya R, Agrawal K, Deems A, Benner B, Hinton A, Shaffer J, Blaser BW, Noonan AM, et al.

(2) The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferonInternational immunopharmacologyJuly 1, 2011Seeds RE, Mukhopadhyay S, Jones IM, Gordon S, Miller JL.

(3) Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactionsJournal of neuropathology and experimental neurologyFebruary 1, 2009Koning N, Swaab DF, Hoek RM, Huitinga I.

(4) A critical function for CD200 in lung immune homeostasis and the severity of influenza infectionNature immunologySeptember 1, 2008Snelgrove RJ, Goulding J, Didierlaurent AM, Lyonga D, Vekaria S, Edwards L, Gwyer E, Sedgwick JD, Barclay AN, Hussell T.

(5) Molecular mechanisms of CD200 inhibition of mast cell activationJournal of immunology (Baltimore, Md. : 1950)December 1, 2004Zhang S, Cherwinski H, Sedgwick JD, Phillips JH.

(6) Down-regulation of the macrophage lineage through interaction with OX2 (CD200)Science (New York, N.Y.)December 1, 2000Hoek RM, Ruuls SR, Murphy CA, Wright GJ, Goddard R, Zurawski SM, Blom B, Homola ME, Streit WJ, Brown MH, et al.

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